牙本质过敏引起的牙蚀性磨损的治疗策略。

Monographs in oral science Pub Date : 2025-01-01 Epub Date: 2025-05-28 DOI:10.1159/000543560
Natasha E West, Nicola X West
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引用次数: 0

摘要

欧洲和中国的数据表明,牙本质过敏(DH)是一种日益严重的口腔疼痛疾病,成人患病率达到50%。病因是多因素的,由于年轻人饮食中酸性食物和饮料的频率增加,侵蚀性牙齿磨损(ETW)变得更加重要。在老年人群中,DH患病率的增加是由人口寿命延长、更健康的生活方式和终生佩戴牙齿的重要牙齿固位率提高所驱动的。DH对生活质量有负面影响。DH发生时,病变局限于牙冠和/或牙根表面,随后发生起始,暴露牙本质小管,这些小管与牙髓相连,DH病因的关键组成部分是ETW。治疗策略从风险评估和采取预防措施开始。现在有经过同行评审的、循证的、有效的牙科治疗方案,特别是非处方家庭使用产品,包括精氨酸、锡和钾,含或不含锡,并耐酸挑战。牙科治疗应被视为与ETW预防治疗相结合的一线治疗。专业治疗是二线治疗方法,尽管有大量的药物被提倡,但优选策略的证据基础薄弱。理想的治疗应该显示立即和持久的疼痛缓解,有效的牙膏显示不同程度的疼痛缓解,立即开始长达2周。治疗的基本原理包括通过牙本质小管闭塞或表面覆盖来改变牙本质小管流体的流动,并设计为承受ETW或化学阻断牙髓神经反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Therapeutic Strategies for Erosive Tooth Wear Related to Dentine Hypersensitivity.

European and Chinese data suggest that dentine hypersensitivity (DH) is an ever increasing, significant oral pain condition, with adult population prevalence figures reaching 50%. Aetiology is multifactorial, with erosive tooth wear (ETW) becoming more important due to increased frequency of dietary acidic food and beverage challenges in younger adults. In older cohorts, DH prevalence increase is driven by population longevity, healthier lifestyles and higher vital tooth retention enduring a lifetime of tooth wear. DH negatively affects quality of life. For DH to occur, the lesion is localized on tooth crown and/or root surface, followed by initiation, exposing dentine tubules which are patent to the pulp, the key component to DH aetiology being ETW. Therapeutic strategies commence with risk assessment and instigation of preventive measures. Peer-reviewed, evidenced-based, efficacious dentifrice treatment regimens are now available, particularly over-the-counter home-use products, including arginine, stannous and potassium, with or without stannous, and resistant to acid challenge. Dentifrices should be regarded as the first-line treatment in conjunction with ETW preventive therapy. Professional treatment is the second-line approach, and although a plethora of agents have been advocated, there is weak evidence base for a preferred strategy. The ideal treatment should demonstrate immediate and long-lasting pain relief, with efficacious dentifrices showing variable degrees of pain relief commencing immediately to up to 2 weeks. The basic principles of treatment involve altering dentinal tubule fluid flow with dentine tubule occlusion or surface coverage and are designed to withstand ETW or chemically blocking pulpal nerve response.

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