西班牙糖尿病患者EQ-5D-5L的心理测量特性

IF 2.9 Q2 HEALTH CARE SCIENCES & SERVICES
Amaia Bilbao-González, Marta González-Sáenz de Tejada, Montse Ferrer, Yolanda Ramallo-Fariña, Miguel Paja-Fano, Carlos García-Forero, Daniela Mestre, Iñigo Gorostiza-Hormaetxe
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引用次数: 0

摘要

背景:EQ-5D-5L五维量表是最广泛使用的基于偏好的通用问卷之一,用于测量与健康相关的生活质量和估计用于经济评估的效用指数。本研究旨在评估西班牙EQ-5D-5L问卷在糖尿病患者中的心理测量特性,评估信度、效度和项目层面的特性,如项目功能。方法:我们纳入了133例糖尿病患者,他们完成了EQ-5D-5L、糖尿病依赖生活质量审计(ADDQoL)、医院焦虑和抑郁量表(HADS)、一个关于一般健康和社会人口统计学的问题以及临床数据。信度采用Cronbach’s alpha评价,项目功能采用项目反应理论(IRT)评价。采用Spearman相关系数检验EQ-5D-5L、ADDQoL、HADS与一般健康问题的收敛效度。我们采用t检验、方差分析、Wilcoxon或Kruskal-Wallis检验,通过比较年龄、性别、BMI、常规体力活动、疾病持续时间、糖化血红蛋白(HbA1c)(%)血糖控制、糖尿病类型、一般健康状况以及焦虑和抑郁水平定义的亚组之间的EQ-5D-5L评分来检验已知组的有效性。结果:信度为0.78。IRT结果支持单维度性,除焦虑/抑郁维度外,其他项目均表现出良好的功能。歧视力最高的项目为日常活动维度,其次为自我照顾维度和流动性维度。EQ-5D-5L具有较好的收敛效度,与ADDQoL、HADS和一般健康状况有较高的相关性。年龄较大、女性、肥胖、没有规律的身体活动、疾病持续时间≥10年、血糖控制不良、一般健康状况较差、焦虑和抑郁水平较高与EQ-5D-5L评分较低相关。结论:这些发现支持EQ-5D-5L在糖尿病患者中具有足够的心理测量特性,支持临床医生和研究人员将其作为结果测量指标和用于经济评估研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Psychometric properties of the EQ-5D-5L in diabetes mellitus patients in Spain.

Background: The EQ-5D-5L five-dimensional instrument, is one of the most widely used generic preference-based questionnaires to measure health-related quality of life and to estimate utility indices for use in economic evaluation. This study aimed to assess the psychometric properties of the Spanish EQ-5D-5L questionnaire in patients with Diabetes Mellitus (DM) assessing reliability, validity, and item-level properties such as item functioning.

Methodology: We included 133 patients with DM who completed the EQ-5D-5L, the Audit on Diabetes-Dependent Quality of Life (ADDQoL), the Hospital Anxiety and Depression Scale (HADS), one question about general health and sociodemographic, and clinical data. The reliability was assessed by Cronbach's alpha, and the item functioning by the item response theory (IRT). Convergent validity was tested using the Spearman correlation coefficient between EQ-5D-5L, ADDQoL, HADS and the general health question. We examined known-groups validity by comparing the EQ-5D-5L scores between subgroups defined by age, gender, BMI, regular physical activity, disease duration, glycemic control by glycosylated blood hemoglobin (HbA1c) (%), type of DM, general health and anxiety and depression level using t-test, ANOVA, Wilcoxon or Kruskal-Wallis tests.

Results: The reliability was supported with a Cronbach's alpha of 0.78. The IRT results supported the unidimensionality and showed adequate item functioning, except for the anxiety/depression dimension. The item with highest discriminatory power was usual activities dimension, followed by self-care and mobility dimensions. The EQ-5D-5L showed adequate convergent validity, with high correlation with the ADDQoL, HADS and general health. Older age, women, obese, no regular physical activity, ≥ 10 years of disease duration, poor glycemic control, poorer general health and higher anxiety and depression level linked with lower EQ-5D-5L scores.

Conclusions: These findings support the adequate psychometric properties of the EQ-5D-5L in patients with DM, supporting its use for clinicians and researchers as an outcome measure and for use in economic evaluation studies.

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来源期刊
Journal of Patient-Reported Outcomes
Journal of Patient-Reported Outcomes Health Professions-Health Information Management
CiteScore
3.80
自引率
7.40%
发文量
120
审稿时长
20 weeks
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