心梗的急性预防:前驱症状识别的识别是解码心梗问题的“罗塞塔石”。

Q3 Medicine
Raymond D Bahr, Frank Breuckmann
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引用次数: 0

摘要

剧烈胸痛之前的胸部不适是临床缺血的标志,表明活心肌处于危险之中,通常发生在心脏骤停或急性心肌梗死(MI)之前。心肌梗死之前的间歇性或口吃症状被称为“前驱症状”。这些症状已被证明与周期性ST改变和反复发作的自发性再灌注和闭塞有关,发生在急性缺血死亡或心脏损伤之前的数小时或数天内。先兆心绞痛的这些症状与缺血预适应或缺血区域周围侧支血管通道开放的预后改善有关。通过识别前驱症状来急性预防心肌梗死是显著减少心脏病发作死亡的机会。早期心脏病发作护理(EHAC)计划强调前驱症状识别,并允许时间向后转移,以防止缺血过程发展为心肌梗死。该策略已被证明可以在低概率组中选择15%的缺血患者,减少不适当的住院,并减少错过心肌梗死的患者从急诊科送回家的数量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute Prevention of the Heart Attack The identification of Prodromal Symptom Recognition as the "Rosetta Stone" in decoding the heart attack problem.

Chest discomfort before severe chest pain represents a clinical ischemia marker and indicates live myocardium in jeopardy and often precedes cardiac arrest or acute myocardial infarction (MI). The intermittent or stuttering symptoms that precede MI are referred to as "prodromal symptoms". These symptoms have been shown to correlate with cyclic ST changes and repeated episodes of spontaneous reperfusion and occlusion, occurring during a period of hours or days before the acute ischemia precedes to death or heart damage. These symptoms of premonitory angina have been associated with improved outcomes due to ischemic pre-conditioning or opening of collateral vascular channels around the area of ischemia. Acute prevention of an MI through prodromal symptoms recognition represents the opportunity for significantly reducing heart attack deaths. The early heart attack care (EHAC) program puts emphasis on prodromal symptom recognition and allows a shift in time backward to prevent the ischemic process from proceeding to MI. This strategy has been shown to pick up the 15% of the patients with ischemia in the low probability group and to reduce inappropriate admissions to the hospital as well as to reduce the number of patients with missed myocardial infarctions being sent home from the emergency department.

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来源期刊
Critical Pathways in Cardiology
Critical Pathways in Cardiology Medicine-Medicine (all)
CiteScore
1.90
自引率
0.00%
发文量
52
期刊介绍: Critical Pathways in Cardiology provides a single source for the diagnostic and therapeutic protocols in use at hospitals worldwide for patients with cardiac disorders. The Journal presents critical pathways for specific diagnoses—complete with evidence-based rationales—and also publishes studies of these protocols" effectiveness.
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