Barrett食管筛查的成本-效果分析：一项系统综述

IF 3.2 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Best Practice & Research Clinical Gastroenterology Pub Date : 2025-03-01 DOI:10.1016/j.bpg.2025.101980

Caroline L. Matchett , Mert Sahinkoc , Jagpreet Chhatwal , John B. Kisiel , Prasad G. Iyer

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引用次数: 0

摘要

Barrett食管筛查对于早期发现食管腺癌至关重要，但最佳策略仍存在争议。本系统综述分析了截至2024年9月评估筛查成本效益的13项研究。与不进行筛查相比，传统的内镜和新兴的非内镜方法都具有成本效益，增量成本-效果比低于标准的支付意愿阈值。与标准内窥镜相比，非内窥镜方法，特别是带有生物标志物的吞下细胞收集装置，显示出更高的成本效益。在疾病流行率较高的人群中，成本效益得到改善。目前的证据支持实施筛查方案，特别是在高危人群中使用非内窥镜方法。未来的研究应侧重于验证风险分层工具，以进一步优化筛查方法。

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Cost effectiveness analysis of Barrett's esophagus screening: A systematic review

Barrett's esophagus screening is critical for early detection of esophageal adenocarcinoma, but optimal strategies remain debated. This systematic review analyzed thirteen studies evaluating screening cost-effectiveness through September 2024. Both traditional endoscopic and emerging non-endoscopic methods were cost-effective compared to no screening, with incremental cost-effectiveness ratios below standard willingness-to-pay thresholds. Non-endoscopic approaches, particularly swallowed cell collection devices with biomarkers, demonstrated superior cost-effectiveness versus standard endoscopy. Cost-effectiveness improved in populations with higher disease prevalence. Current evidence supports implementing screening programs, especially using non-endoscopic methods in high-risk populations. Future research should focus on validating risk stratification tools to further optimize screening approaches.

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来源期刊

Best Practice & Research Clinical Gastroenterology 医学-胃肠肝病学

CiteScore

5.50

自引率

0.00%

发文量

审稿时长

69 days

期刊介绍： Each topic-based issue of Best Practice & Research Clinical Gastroenterology will provide a comprehensive review of current clinical practice and thinking within the specialty of gastroenterology.