1例使用派姆单抗治疗的隐源性穿透性主动脉溃疡患者胸支假体置入后主动脉食管瘘

IF 0.7 Q4 SURGERY

Journal of Vascular Surgery Cases Innovations and Techniques Pub Date : 2025-05-06 DOI:10.1016/j.jvscit.2025.101837

Sarah Kim BA , Patrick D. Conroy MD , Mark Zemela MD , Bruce L. Tjaden Jr. MD

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引用次数: 0

摘要

穿透性主动脉溃疡并不常见，而且会危及生命。我们描述的情况下，一个67岁的男子谁提出发烧和寒战，并被发现在计算机断层扫描有一个胸椎穿透性主动脉溃疡。患者接受了胸椎分支假体置入术，术后并发回结肠假性动脉瘤、进行性主动脉炎和致命的主动脉食管瘘。在该患者复杂的医学表现背景下，讨论了在多重混杂因素的背景下对穿透性主动脉溃疡的治疗，重点是派姆单抗在其疾病进展中的潜在作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Aortoesophageal fistula following thoracic branch endoprosthesis for cryptogenic penetrating aortic ulcer in a patient on pembrolizumab

Penetrating aortic ulcers are uncommon and life-threatening. We describe the case of a 67-year-old man who presented with fever and chills and was found on computed tomographic scan to have a thoracic penetrating aortic ulcer. The patient underwent placement of a thoracic branch endoprosthesis, with a postoperative course complicated by ileocolic pseudoaneurysm, progressive aortitis, and a fatal aortoesophageal fistula. The management of penetrating aortic ulcer in the setting of multiple confounding factors is discussed in the context of this patient’s complex medical presentation, with a focus on the potential role of pembrolizumab in his disease progression.

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来源期刊

Journal of Vascular Surgery Cases Innovations and Techniques SURGERY-

CiteScore

1.00

自引率

14.30%

发文量

219

审稿时长

29 weeks

期刊介绍： Journal of Vascular Surgery Cases and Innovative Techniques is a surgical journal dedicated to publishing peer review high quality case reports, vascular images and innovative techniques related to all aspects of arterial, venous, and lymphatic diseases and disorders, including vascular trauma, malformations, wound care and the placement and maintenance of arterio-venous dialysis accesses with an emphasis on the practicing clinician. The Journal seeks to provide novel and timely information to vascular surgeons, interventionalists, phlebologists, wound care specialists, and allied health professionals involved with the management of patients with the entire spectrum of vascular disorders.