常染色体显性多囊肾病1例罕见狼疮肾炎诊断报告。

IF 0.8 4区医学 Q4 UROLOGY & NEPHROLOGY

Iranian journal of kidney diseases Pub Date : 2025-05-16 DOI:10.52547/n8rjp713

Sareh Khamar-Moghadam, Soroush Mostafavi, Seyyedeh Mina Hejazian, Shahrzad Ossareh

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引用次数: 0

摘要

常染色体显性多囊肾病（ADPKD）是一种广泛存在的遗传性多囊肾病，其患病率约为千分之一。然而，很少有关于ADPKD与肾病范围蛋白尿（如狼疮肾炎（LN））相关的报道。在本研究中，我们报告了一例ADPKD患者，其表现为尿蛋白排泄突然增加，抗双链DNA和抗核抗体检测呈阳性。最后，基于经皮超声引导下的肾活检证实LN的存在。该报告建议临床医生定期评估ADPKD患者，并在出现肾病综合征等不寻常症状的病例中进行补充临床和实验室调查。

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The Diagnosis of Lupus Nephritis in A Patient with Autosomal Dominant Polycystic Kidney Disease: A Rare Case Report.

Autosomal dominant polycystic kidney disease (ADPKD), as a widespread inherited cystic kidney disease has a prevalence of ~1/1000 live births. However, there are rare reports of the association of ADPKD with nephrotic range proteinuria such as lupus nephritis (LN). In this study, we report a patient with ADPKD who manifested a sudden increase of urinary protein excretion with positive anti-double stranded DNA and antinuclear antibody tests. Finally, based on percutaneous ultrasound-guided renal biopsy LN was proved. This report advises clinicians to evaluate ADPKD patients periodically and perform complementary clinical and laboratory investigations in cases with unusual presentations such as nephrotic syndrome.

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来源期刊

Iranian journal of kidney diseases UROLOGY & NEPHROLOGY-

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Iranian Journal of Kidney Diseases (IJKD), a peer-reviewed journal in English, is the official publication of the Iranian Society of Nephrology. The aim of the IJKD is the worldwide reflection of the knowledge produced by the scientists and clinicians in nephrology. Published quarterly, the IJKD provides a new platform for advancement of the field. The journal’s objective is to serve as a focal point for debates and exchange of knowledge and experience among researchers in a global context. Original papers, case reports, and invited reviews on all aspects of the kidney diseases, hypertension, dialysis, and transplantation will be covered by the IJKD. Research on the basic science, clinical practice, and socio-economics of renal health are all welcomed by the editors of the journal.