{"title":"sglt2i相关围手术期酮症酸中毒(SAPKA) /糖尿病酮症酸中毒(EDKA)的处理","authors":"Louise Y. Wen M.D","doi":"10.1016/j.jclinane.2025.111854","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>This infographic reviews the risk of perioperative euglycemic diabetic ketoacidosis (EKDA) associated with sodium-glucose co-transporter 2 inhibitor (SGLT2i), which is more specifically called SGLT2i-associated perioperative ketoacidosis (SAPKA)<span><span><sup>1</sup></span><svg><path></path></svg></span>. The incidence of SAPKA/perioperative EDKA is estimated to be 0.17 % for nonemergent procedures and 1.1 % for emergent procedures<span><span><sup>2</sup></span><svg><path></path></svg></span>. The goal is to guide both anesthesia and surgery teams regarding the perioperative management of SGLT2i's to mitigate the risk of SAPKA/EDKA.</div></div>","PeriodicalId":15506,"journal":{"name":"Journal of Clinical Anesthesia","volume":"105 ","pages":"Article 111854"},"PeriodicalIF":5.0000,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Management of SGLT2i-associated perioperative ketoacidosis (SAPKA) / Euglycemic Diabetic Ketoacidosis (EDKA)\",\"authors\":\"Louise Y. Wen M.D\",\"doi\":\"10.1016/j.jclinane.2025.111854\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>This infographic reviews the risk of perioperative euglycemic diabetic ketoacidosis (EKDA) associated with sodium-glucose co-transporter 2 inhibitor (SGLT2i), which is more specifically called SGLT2i-associated perioperative ketoacidosis (SAPKA)<span><span><sup>1</sup></span><svg><path></path></svg></span>. The incidence of SAPKA/perioperative EDKA is estimated to be 0.17 % for nonemergent procedures and 1.1 % for emergent procedures<span><span><sup>2</sup></span><svg><path></path></svg></span>. The goal is to guide both anesthesia and surgery teams regarding the perioperative management of SGLT2i's to mitigate the risk of SAPKA/EDKA.</div></div>\",\"PeriodicalId\":15506,\"journal\":{\"name\":\"Journal of Clinical Anesthesia\",\"volume\":\"105 \",\"pages\":\"Article 111854\"},\"PeriodicalIF\":5.0000,\"publicationDate\":\"2025-05-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Anesthesia\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S095281802500114X\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Anesthesia","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S095281802500114X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
This infographic reviews the risk of perioperative euglycemic diabetic ketoacidosis (EKDA) associated with sodium-glucose co-transporter 2 inhibitor (SGLT2i), which is more specifically called SGLT2i-associated perioperative ketoacidosis (SAPKA)1. The incidence of SAPKA/perioperative EDKA is estimated to be 0.17 % for nonemergent procedures and 1.1 % for emergent procedures2. The goal is to guide both anesthesia and surgery teams regarding the perioperative management of SGLT2i's to mitigate the risk of SAPKA/EDKA.
期刊介绍:
The Journal of Clinical Anesthesia (JCA) addresses all aspects of anesthesia practice, including anesthetic administration, pharmacokinetics, preoperative and postoperative considerations, coexisting disease and other complicating factors, cost issues, and similar concerns anesthesiologists contend with daily. Exceptionally high standards of presentation and accuracy are maintained.
The core of the journal is original contributions on subjects relevant to clinical practice, and rigorously peer-reviewed. Highly respected international experts have joined together to form the Editorial Board, sharing their years of experience and clinical expertise. Specialized section editors cover the various subspecialties within the field. To keep your practical clinical skills current, the journal bridges the gap between the laboratory and the clinical practice of anesthesiology and critical care to clarify how new insights can improve daily practice.