Zoë Panchal, Joseph Sakai, Andrea N Goldstein-Piekarski, Jarrod M Ellingson, William Iacono, Robin P Corley, Scott Vrieze, Christian J Hopfer, John K Hewitt, Matt K McGue, J Megan Ross
{"title":"精神健康、物质使用以及与近期使用大麻睡眠相关的相关因素：一项双胞对照研究","authors":"Zoë Panchal, Joseph Sakai, Andrea N Goldstein-Piekarski, Jarrod M Ellingson, William Iacono, Robin P Corley, Scott Vrieze, Christian J Hopfer, John K Hewitt, Matt K McGue, J Megan Ross","doi":"10.1080/15402002.2025.2508770","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>To examine: 1) cross-sectional associations between past-month use of cannabis for sleep with mental health, substance use, and related factors in adults and 2) the role of genetic and early environmental factors shared by twins (familial confounds) in explaining significant associations.</p><p><strong>Methods: </strong>In a population-based sample of adult twins (<i>n</i> = 3,165, M<sub>age</sub>36.7) we ran regression (phenotypic) and multilevel (co-twin control) models examining associations between past-month use of cannabis for sleep without comes of interest. We controlled for cannabis frequency and sleep quality except when each was the outcome of interest.</p><p><strong>Results: </strong>Recent use of cannabis for sleep was associated with multiple mental health, substance use, and related factors in phenotypic models. In co-twincontrol models, within-family effects were significant between using cannabis for sleep with more problems from cannabis use, higher cannabis frequency, worse sleep quality, and more frequent use of alcohol and medication for sleep.</p><p><strong>Conclusions: </strong>Familial confounds may explain many, but not all, associations between recent use of cannabis for sleep and mental health, substance use, and related factors. Longitudinal work is needed to clarify the directionality of associations not explained by familial confounds, and whether they are risks of using cannabis for sleep.</p>","PeriodicalId":55393,"journal":{"name":"Behavioral Sleep Medicine","volume":" ","pages":"1-13"},"PeriodicalIF":2.2000,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mental Health, Substance Use, and Related Factors Associated with Recent Use of Cannabis for Sleep: A Co-Twin Control Study.\",\"authors\":\"Zoë Panchal, Joseph Sakai, Andrea N Goldstein-Piekarski, Jarrod M Ellingson, William Iacono, Robin P Corley, Scott Vrieze, Christian J Hopfer, John K Hewitt, Matt K McGue, J Megan Ross\",\"doi\":\"10.1080/15402002.2025.2508770\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To examine: 1) cross-sectional associations between past-month use of cannabis for sleep with mental health, substance use, and related factors in adults and 2) the role of genetic and early environmental factors shared by twins (familial confounds) in explaining significant associations.</p><p><strong>Methods: </strong>In a population-based sample of adult twins (<i>n</i> = 3,165, M<sub>age</sub>36.7) we ran regression (phenotypic) and multilevel (co-twin control) models examining associations between past-month use of cannabis for sleep without comes of interest. We controlled for cannabis frequency and sleep quality except when each was the outcome of interest.</p><p><strong>Results: </strong>Recent use of cannabis for sleep was associated with multiple mental health, substance use, and related factors in phenotypic models. In co-twincontrol models, within-family effects were significant between using cannabis for sleep with more problems from cannabis use, higher cannabis frequency, worse sleep quality, and more frequent use of alcohol and medication for sleep.</p><p><strong>Conclusions: </strong>Familial confounds may explain many, but not all, associations between recent use of cannabis for sleep and mental health, substance use, and related factors. Longitudinal work is needed to clarify the directionality of associations not explained by familial confounds, and whether they are risks of using cannabis for sleep.</p>\",\"PeriodicalId\":55393,\"journal\":{\"name\":\"Behavioral Sleep Medicine\",\"volume\":\" \",\"pages\":\"1-13\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-05-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Behavioral Sleep Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/15402002.2025.2508770\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavioral Sleep Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/15402002.2025.2508770","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Mental Health, Substance Use, and Related Factors Associated with Recent Use of Cannabis for Sleep: A Co-Twin Control Study.
Objectives: To examine: 1) cross-sectional associations between past-month use of cannabis for sleep with mental health, substance use, and related factors in adults and 2) the role of genetic and early environmental factors shared by twins (familial confounds) in explaining significant associations.
Methods: In a population-based sample of adult twins (n = 3,165, Mage36.7) we ran regression (phenotypic) and multilevel (co-twin control) models examining associations between past-month use of cannabis for sleep without comes of interest. We controlled for cannabis frequency and sleep quality except when each was the outcome of interest.
Results: Recent use of cannabis for sleep was associated with multiple mental health, substance use, and related factors in phenotypic models. In co-twincontrol models, within-family effects were significant between using cannabis for sleep with more problems from cannabis use, higher cannabis frequency, worse sleep quality, and more frequent use of alcohol and medication for sleep.
Conclusions: Familial confounds may explain many, but not all, associations between recent use of cannabis for sleep and mental health, substance use, and related factors. Longitudinal work is needed to clarify the directionality of associations not explained by familial confounds, and whether they are risks of using cannabis for sleep.
期刊介绍：
Behavioral Sleep Medicine addresses behavioral dimensions of normal and abnormal sleep mechanisms and the prevention, assessment, and treatment of sleep disorders and associated behavioral and emotional problems. Standards for interventions acceptable to this journal are guided by established principles of behavior change. Intending to serve as the intellectual home for the application of behavioral/cognitive science to the study of normal and disordered sleep, the journal paints a broad stroke across the behavioral sleep medicine landscape. Its content includes scholarly investigation of such areas as normal sleep experience, insomnia, the relation of daytime functioning to sleep, parasomnias, circadian rhythm disorders, treatment adherence, pediatrics, and geriatrics. Multidisciplinary approaches are particularly welcome. The journal’ domain encompasses human basic, applied, and clinical outcome research. Behavioral Sleep Medicine also embraces methodological diversity, spanning innovative case studies, quasi-experimentation, randomized trials, epidemiology, and critical reviews.
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