2014-2023年，荷兰毒物信息中心报告的青少年中涉及精神活性药物的中毒数量大幅增加

IF 4.4 2区医学 Q1 SUBSTANCE ABUSE

International Journal of Drug Policy Pub Date : 2025-05-23 DOI:10.1016/j.drugpo.2025.104860

Ilze MJ Thoonen , Saskia J Rietjens , Arjen Koppen , Dylan W de Lange , Johanna J Nugteren-van Lonkhuyzen

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引用次数: 0

摘要

精神活性药物的使用在世界范围内一直在增加，青少年和年轻人占吸毒者的很大一部分。迄今为止，关于青少年精神活性药物中毒趋势的信息有限，特别是关于新型精神活性物质（NPS）的信息。方法回顾性研究2014-2023年荷兰毒物信息中心（DPIC）报告的13-17岁青少年精神活性药物中毒特征。收集患者（年龄和性别）和暴露特征（涉及精神活性药物、暴露的日期和月份）的数据。结果2014-2023年咨询了978起青少年精神药物中毒事件。从2014年到2023年，中毒事件的数量显著增加(RR = 1.14, 95% CI: 1.11-1.16, p <；0.001)。增幅最大的是大麻产品中毒事件的数量（增加208%，2014年：n = 13，而2023年：n = 40）（特别是可食用的）、MDMA（增加100%，2014年：n = 27，而2023年：n = 54）和3-甲基甲卡西酮（3-MMC）（2014年：n = 0, 2019年：n = 2，而2023年：n = 24）。此外，咨询DPIC的NPS种类也有所增加，2014年报告了1种NPS， 2023年报告了13种NPS。结论2014-2023年青少年精神药物中毒人数呈明显上升趋势。青少年中精神活性药物中毒的增加，以及不同类型的NPS数量的增加令人担忧，因为特别是NPS的毒性往往是未知的。更多关于潜在危险的教育以及即将到来的立法改革可能会扭转这一趋势。

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Strong increase in the number of intoxications involving psychoactive drugs among adolescents reported to the Dutch Poisons Information Center from 2014–2023

Introduction

The use of psychoactive drugs has been increasing worldwide, with adolescents and young adults accounting for a large share of people who use drugs. To date, there is limited information on trends of intoxications with psychoactive drugs among adolescents, particularly with regard to New Psychoactive Substances (NPS).

Methods

A retrospective study was performed from 2014-2023 to characterize intoxications with psychoactive drugs among adolescents aged 13-17 years, reported to the Dutch Poisons Information Center (DPIC). Data were collected on patient (age and gender) and exposure characteristics (psychoactive drugs involved, day and month of exposure).

Results

From 2014-2023 the DPIC was consulted on 978 poisoning events among adolescents involving psychoactive drugs. A significant increase in the number of poisoning events was observed from 2014 to 2023 (RR = 1.14, 95 % CI: 1.11-1.16, p < 0.001). The largest increase was observed in the number of poisoning events with cannabis products (208 % increase, 2014: n = 13 vs. 2023: n = 40) (especially edibles), MDMA (100 % increase, 2014: n = 27 vs. 2023: n = 54) and 3-methylmethcathinone (3-MMC) (2014: n = 0, 2019: n = 2 vs. 2023: n = 24). There was also an increase in the variety of NPS the DPIC was consulted on, with 1 type of NPS reported in 2014 and 13 in 2023.

Conclusions

In this study, a strong increase was observed in the number of intoxications with psychoactive drugs among adolescents from 2014-2023. The increase in intoxications with psychoactive drugs among adolescents, as well as the increase in the number of different types of NPS is worrying, since toxicity of especially NPS is often unknown. More education on the potential dangers along with upcoming legislative changes, might reverse this trend.

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来源期刊

International Journal of Drug Policy SUBSTANCE ABUSE-

CiteScore

7.80

自引率

11.40%

发文量

307

审稿时长

62 days

期刊介绍： The International Journal of Drug Policy provides a forum for the dissemination of current research, reviews, debate, and critical analysis on drug use and drug policy in a global context. It seeks to publish material on the social, political, legal, and health contexts of psychoactive substance use, both licit and illicit. The journal is particularly concerned to explore the effects of drug policy and practice on drug-using behaviour and its health and social consequences. It is the policy of the journal to represent a wide range of material on drug-related matters from around the world.