{"title":"对[11C]AZD4747（一种CNS渗透KRASG12c抑制剂）生产质量管理规范验证的更正","authors":"","doi":"10.1002/jlcr.4149","DOIUrl":null,"url":null,"abstract":"<p>J Labelled Comp Radiopharm. 2024 May 30;67(6):245-249.</p><p>The scheme depicting the labelling of [<sup>11</sup>C]AZD4747 shows the incorrect structure for both the precursor and the product. The position of the nitrogen atom and the stereochemistry of the seven-membered ring have been corrected.</p><p>The corrected reaction scheme is depicted below.<span><!--EMPTY></span></p><p>We apologize for this error.</p>","PeriodicalId":16288,"journal":{"name":"Journal of labelled compounds & radiopharmaceuticals","volume":"68 5-6","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jlcr.4149","citationCount":"0","resultStr":"{\"title\":\"Correction to Validation of a Good Manufacturing Practice Procedure for the Production of [11C]AZD4747, a CNS Penetrant KRASG12c Inhibitor\",\"authors\":\"\",\"doi\":\"10.1002/jlcr.4149\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>J Labelled Comp Radiopharm. 2024 May 30;67(6):245-249.</p><p>The scheme depicting the labelling of [<sup>11</sup>C]AZD4747 shows the incorrect structure for both the precursor and the product. The position of the nitrogen atom and the stereochemistry of the seven-membered ring have been corrected.</p><p>The corrected reaction scheme is depicted below.<span><!--EMPTY></span></p><p>We apologize for this error.</p>\",\"PeriodicalId\":16288,\"journal\":{\"name\":\"Journal of labelled compounds & radiopharmaceuticals\",\"volume\":\"68 5-6\",\"pages\":\"\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-05-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jlcr.4149\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of labelled compounds & radiopharmaceuticals\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jlcr.4149\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of labelled compounds & radiopharmaceuticals","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jlcr.4149","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Correction to Validation of a Good Manufacturing Practice Procedure for the Production of [11C]AZD4747, a CNS Penetrant KRASG12c Inhibitor
J Labelled Comp Radiopharm. 2024 May 30;67(6):245-249.
The scheme depicting the labelling of [11C]AZD4747 shows the incorrect structure for both the precursor and the product. The position of the nitrogen atom and the stereochemistry of the seven-membered ring have been corrected.
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