{"title":"股骨内翻畸形在中国男性骨关节炎患者中占主导地位，在功能性膝关节表型上具有地理差异。","authors":"Songlin Li, Jiaming He, Weibo Zheng, Xuezhou Li, Jie Yang, Zhe Li, Houyi Sun, Zhuang Miao, Wenwei Qian, Peilai Liu, Qunshan Lu","doi":"10.1002/ksa.12693","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Purpose</h3>\n \n <p>The aims of this study were to generalise the distribution and sex differences in functional knee phenotypes in a Chinese osteoarthritis (OA) population and to compare the distributions of functional knee phenotypes across geographic regions.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Knee phenotypes were evaluated according to Hirschmann's classification in 908 knees with OA, and the correlations among the hip–knee–ankle angle (HKA), femoral mechanical angle (FMA) and tibial mechanical angle (TMA) and their differences between the sexes were described. Studies reporting the distributions of functional knee phenotypes for arthritic knees were included to compare the variability in geographic distribution.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The average values (males, females) of the HKA (173.1 ± 5.4°, 174.0 ± 6.9°), FMA (90.5 ± 2.9°, 91.6 ± 3.5°), and TMA (85.7 ± 3.1°, 85.7 ± 3.6°) demonstrated that the Chinese OA population tended towards femoral and tibial varus deformities in both males and females. A total of 145 functional knee phenotypes were identified in all 908 knees, comprising 68 types in males and 136 types in females. The most common phenotypes were VAR<sub>HKA</sub>6° + VAR<sub>FMA</sub>3° + NEU<sub>TMA</sub>0° (5.7%) for all knees, VAR<sub>HKA</sub>3° + NEU<sub>FMA</sub>0° + NEU<sub>TMA</sub>0° (7.4%) for males and VAR<sub>HKA</sub>6° + VAR<sub>FMA</sub>3° + NEU<sub>TMA</sub>0° (5.4%) for females. The incidence of femoral varus deformity was greater than that of tibial varus deformity in 48.4% of males and 36.5% of females, and the incidence of tibial varus deformity was greater than that of femoral varus deformity in 24.7% of males and 35.2% of females. Seven studies including 16,395 knees were identified. The main femoral and tibial phenotypes in different geographic regions were VAR<sub>FMA</sub>3° and NEU<sub>TMA</sub>0°, but their proportional distributions differed significantly.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Sex differences in the functional knee phenotypes of OA patients in China were identified. Femoral varus deformity was more common than tibial varus deformity in males, whereas the difference was minimal in females. Moreover, functional knee phenotypes varied significantly across geographic regions.</p>\n </section>\n \n <section>\n \n <h3> Level of Evidence</h3>\n \n <p>Level IV.</p>\n </section>\n </div>","PeriodicalId":17880,"journal":{"name":"Knee Surgery, Sports Traumatology, Arthroscopy","volume":"33 9","pages":"3310-3323"},"PeriodicalIF":5.0000,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Femoral varus deformity predominates in male Chinese osteoarthritis patients with geographic variability in functional knee phenotypes\",\"authors\":\"Songlin Li, Jiaming He, Weibo Zheng, Xuezhou Li, Jie Yang, Zhe Li, Houyi Sun, Zhuang Miao, Wenwei Qian, Peilai Liu, Qunshan Lu\",\"doi\":\"10.1002/ksa.12693\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Purpose</h3>\\n \\n <p>The aims of this study were to generalise the distribution and sex differences in functional knee phenotypes in a Chinese osteoarthritis (OA) population and to compare the distributions of functional knee phenotypes across geographic regions.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Knee phenotypes were evaluated according to Hirschmann's classification in 908 knees with OA, and the correlations among the hip–knee–ankle angle (HKA), femoral mechanical angle (FMA) and tibial mechanical angle (TMA) and their differences between the sexes were described. Studies reporting the distributions of functional knee phenotypes for arthritic knees were included to compare the variability in geographic distribution.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The average values (males, females) of the HKA (173.1 ± 5.4°, 174.0 ± 6.9°), FMA (90.5 ± 2.9°, 91.6 ± 3.5°), and TMA (85.7 ± 3.1°, 85.7 ± 3.6°) demonstrated that the Chinese OA population tended towards femoral and tibial varus deformities in both males and females. A total of 145 functional knee phenotypes were identified in all 908 knees, comprising 68 types in males and 136 types in females. The most common phenotypes were VAR<sub>HKA</sub>6° + VAR<sub>FMA</sub>3° + NEU<sub>TMA</sub>0° (5.7%) for all knees, VAR<sub>HKA</sub>3° + NEU<sub>FMA</sub>0° + NEU<sub>TMA</sub>0° (7.4%) for males and VAR<sub>HKA</sub>6° + VAR<sub>FMA</sub>3° + NEU<sub>TMA</sub>0° (5.4%) for females. The incidence of femoral varus deformity was greater than that of tibial varus deformity in 48.4% of males and 36.5% of females, and the incidence of tibial varus deformity was greater than that of femoral varus deformity in 24.7% of males and 35.2% of females. Seven studies including 16,395 knees were identified. The main femoral and tibial phenotypes in different geographic regions were VAR<sub>FMA</sub>3° and NEU<sub>TMA</sub>0°, but their proportional distributions differed significantly.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Sex differences in the functional knee phenotypes of OA patients in China were identified. Femoral varus deformity was more common than tibial varus deformity in males, whereas the difference was minimal in females. Moreover, functional knee phenotypes varied significantly across geographic regions.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Level of Evidence</h3>\\n \\n <p>Level IV.</p>\\n </section>\\n </div>\",\"PeriodicalId\":17880,\"journal\":{\"name\":\"Knee Surgery, Sports Traumatology, Arthroscopy\",\"volume\":\"33 9\",\"pages\":\"3310-3323\"},\"PeriodicalIF\":5.0000,\"publicationDate\":\"2025-05-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Knee Surgery, Sports Traumatology, Arthroscopy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://esskajournals.onlinelibrary.wiley.com/doi/10.1002/ksa.12693\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Knee Surgery, Sports Traumatology, Arthroscopy","FirstCategoryId":"3","ListUrlMain":"https://esskajournals.onlinelibrary.wiley.com/doi/10.1002/ksa.12693","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
Femoral varus deformity predominates in male Chinese osteoarthritis patients with geographic variability in functional knee phenotypes
Purpose
The aims of this study were to generalise the distribution and sex differences in functional knee phenotypes in a Chinese osteoarthritis (OA) population and to compare the distributions of functional knee phenotypes across geographic regions.
Methods
Knee phenotypes were evaluated according to Hirschmann's classification in 908 knees with OA, and the correlations among the hip–knee–ankle angle (HKA), femoral mechanical angle (FMA) and tibial mechanical angle (TMA) and their differences between the sexes were described. Studies reporting the distributions of functional knee phenotypes for arthritic knees were included to compare the variability in geographic distribution.
Results
The average values (males, females) of the HKA (173.1 ± 5.4°, 174.0 ± 6.9°), FMA (90.5 ± 2.9°, 91.6 ± 3.5°), and TMA (85.7 ± 3.1°, 85.7 ± 3.6°) demonstrated that the Chinese OA population tended towards femoral and tibial varus deformities in both males and females. A total of 145 functional knee phenotypes were identified in all 908 knees, comprising 68 types in males and 136 types in females. The most common phenotypes were VARHKA6° + VARFMA3° + NEUTMA0° (5.7%) for all knees, VARHKA3° + NEUFMA0° + NEUTMA0° (7.4%) for males and VARHKA6° + VARFMA3° + NEUTMA0° (5.4%) for females. The incidence of femoral varus deformity was greater than that of tibial varus deformity in 48.4% of males and 36.5% of females, and the incidence of tibial varus deformity was greater than that of femoral varus deformity in 24.7% of males and 35.2% of females. Seven studies including 16,395 knees were identified. The main femoral and tibial phenotypes in different geographic regions were VARFMA3° and NEUTMA0°, but their proportional distributions differed significantly.
Conclusions
Sex differences in the functional knee phenotypes of OA patients in China were identified. Femoral varus deformity was more common than tibial varus deformity in males, whereas the difference was minimal in females. Moreover, functional knee phenotypes varied significantly across geographic regions.
期刊介绍：
Few other areas of orthopedic surgery and traumatology have undergone such a dramatic evolution in the last 10 years as knee surgery, arthroscopy and sports traumatology. Ranked among the top 33% of journals in both Orthopedics and Sports Sciences, the goal of this European journal is to publish papers about innovative knee surgery, sports trauma surgery and arthroscopy. Each issue features a series of peer-reviewed articles that deal with diagnosis and management and with basic research. Each issue also contains at least one review article about an important clinical problem. Case presentations or short notes about technical innovations are also accepted for publication.
The articles cover all aspects of knee surgery and all types of sports trauma; in addition, epidemiology, diagnosis, treatment and prevention, and all types of arthroscopy (not only the knee but also the shoulder, elbow, wrist, hip, ankle, etc.) are addressed. Articles on new diagnostic techniques such as MRI and ultrasound and high-quality articles about the biomechanics of joints, muscles and tendons are included. Although this is largely a clinical journal, it is also open to basic research with clinical relevance.
Because the journal is supported by a distinguished European Editorial Board, assisted by an international Advisory Board, you can be assured that the journal maintains the highest standards.
Official Clinical Journal of the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA).
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