三叉神经痛微血管减压术有效与无效的三叉神经矢状角比较。

IF 1.5 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Current Problems in Diagnostic Radiology Pub Date : 2025-05-11 DOI:10.1067/j.cpradiol.2025.05.003

Shehbaz Ansari MD, Brian H. Mu MD, Eric R. Basappa MD, Melih Akyuz MD, Miral D. Jhaveri MD MBA, Santhosh Gaddikeri MD

{"title":"三叉神经痛微血管减压术有效与无效的三叉神经矢状角比较。","authors":"Shehbaz Ansari MD, Brian H. Mu MD, Eric R. Basappa MD, Melih Akyuz MD, Miral D. Jhaveri MD MBA, Santhosh Gaddikeri MD","doi":"10.1067/j.cpradiol.2025.05.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Background and purpose</h3><div>The sagittal angle of the trigeminal nerve at the porus trigeminus (SATNaPT) has been described as abnormally hyperacute in a subset of patients with trigeminal neuralgia and proposed as a potential marker for the likelihood of poor microvascular decompression (MVD) outcomes. The purpose of this study is to replicate these results and evaluate this hypothesized association by comparing the SATNaPT between MVD responders and non-responders.</div></div><div><h3>Materials and methods</h3><div>At a single institution, 80 patients with a clinical diagnosis of trigeminal neuralgia, surgical intervention with MVD, and available adequate high-resolution T2 imaging were identified. SATNaPT was measured between the cisternal segment of the trigeminal nerve and its uppermost branch in the Meckel cave by a blinded observer. These data were evaluated for normality of distribution and compared between responders and non-responders to MVD as well as between affected and unaffected sides. Non-response to MVD was defined as persistent pain requiring continuous medication postoperatively or progression to secondary interventions.</div></div><div><h3>Results</h3><div>There were 43 (52.5 %) responders and 39 (47.5 %) non-responders to MVD. Two patients had bilateral disease for 82 affected sides and 78 unaffected sides. The mean SATNaPT among responders was 150.5° (SD: ±10.6°), which was not significantly different (<em>p</em> = 0.21) from the 153.1° (SD: ±8.0°) mean angle in non-responders. Mean SATNaPT was not significantly different (<em>p</em> = 0.10) between the affected (mean: 151.7°, SD: ±9.5°) and the unaffected (mean: 153.1°, SD: ±10.0°) sides.</div></div><div><h3>Conclusions</h3><div>Our study did not replicate the bimodal distribution of the SATNaPT in cTN patients. No statistically significant difference was noted in the SATNaPT between responders and non-responders to MVD or between symptomatic and asymptomatic sides.</div></div>","PeriodicalId":51617,"journal":{"name":"Current Problems in Diagnostic Radiology","volume":"54 5","pages":"Pages 585-589"},"PeriodicalIF":1.5000,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of sagittal angle of trigeminal nerve at porus trigeminus between responders and non-responders to microvascular decompression surgery in patients with trigeminal neuralgia\",\"authors\":\"Shehbaz Ansari MD, Brian H. Mu MD, Eric R. Basappa MD, Melih Akyuz MD, Miral D. Jhaveri MD MBA, Santhosh Gaddikeri MD\",\"doi\":\"10.1067/j.cpradiol.2025.05.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background and purpose</h3><div>The sagittal angle of the trigeminal nerve at the porus trigeminus (SATNaPT) has been described as abnormally hyperacute in a subset of patients with trigeminal neuralgia and proposed as a potential marker for the likelihood of poor microvascular decompression (MVD) outcomes. The purpose of this study is to replicate these results and evaluate this hypothesized association by comparing the SATNaPT between MVD responders and non-responders.</div></div><div><h3>Materials and methods</h3><div>At a single institution, 80 patients with a clinical diagnosis of trigeminal neuralgia, surgical intervention with MVD, and available adequate high-resolution T2 imaging were identified. SATNaPT was measured between the cisternal segment of the trigeminal nerve and its uppermost branch in the Meckel cave by a blinded observer. These data were evaluated for normality of distribution and compared between responders and non-responders to MVD as well as between affected and unaffected sides. Non-response to MVD was defined as persistent pain requiring continuous medication postoperatively or progression to secondary interventions.</div></div><div><h3>Results</h3><div>There were 43 (52.5 %) responders and 39 (47.5 %) non-responders to MVD. Two patients had bilateral disease for 82 affected sides and 78 unaffected sides. The mean SATNaPT among responders was 150.5° (SD: ±10.6°), which was not significantly different (<em>p</em> = 0.21) from the 153.1° (SD: ±8.0°) mean angle in non-responders. Mean SATNaPT was not significantly different (<em>p</em> = 0.10) between the affected (mean: 151.7°, SD: ±9.5°) and the unaffected (mean: 153.1°, SD: ±10.0°) sides.</div></div><div><h3>Conclusions</h3><div>Our study did not replicate the bimodal distribution of the SATNaPT in cTN patients. No statistically significant difference was noted in the SATNaPT between responders and non-responders to MVD or between symptomatic and asymptomatic sides.</div></div>\",\"PeriodicalId\":51617,\"journal\":{\"name\":\"Current Problems in Diagnostic Radiology\",\"volume\":\"54 5\",\"pages\":\"Pages 585-589\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-05-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Problems in Diagnostic Radiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0363018825000933\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Problems in Diagnostic Radiology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0363018825000933","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 0

摘要

背景和目的：三叉神经三叉孔处矢状角（SATNaPT）在三叉神经痛患者中被描述为异常超急性，并被认为是微血管减压（MVD）预后不良可能性的潜在标志。本研究的目的是通过比较MVD应答者和无应答者之间的SATNaPT来重复这些结果并评估这种假设的关联。材料和方法：在同一家机构，我们确定了80例临床诊断为三叉神经痛、MVD手术干预和可用的高分辨率T2成像的患者。采用盲法测量三叉神经池段与Meckel洞中三叉神经最上分支之间的SATNaPT。评估这些数据分布的正态性，并比较MVD应答者和无应答者以及受影响侧和未受影响侧之间的差异。MVD无反应定义为术后持续疼痛需要持续用药或进展到二次干预。结果：MVD有应答者43例（52.5%），无应答者39例（47.5%）。2例患者有82侧受累侧和78侧未受累侧双侧病变。应答者的平均SATNaPT为150.5°（SD：±10.6°），与无应答者的平均SATNaPT为153.1°（SD：±8.0°），差异无统计学意义（p = 0.21）。受影响侧（平均值：151.7°，SD：±9.5°）和未受影响侧（平均值：153.1°，SD：±10.0°）的平均SATNaPT无显著差异（p = 0.10）。结论：我们的研究没有重复cTN患者SATNaPT的双峰分布。在MVD应答者和无应答者之间，或在症状侧和无症状侧之间，SATNaPT没有统计学上的显著差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Comparison of sagittal angle of trigeminal nerve at porus trigeminus between responders and non-responders to microvascular decompression surgery in patients with trigeminal neuralgia

Background and purpose

The sagittal angle of the trigeminal nerve at the porus trigeminus (SATNaPT) has been described as abnormally hyperacute in a subset of patients with trigeminal neuralgia and proposed as a potential marker for the likelihood of poor microvascular decompression (MVD) outcomes. The purpose of this study is to replicate these results and evaluate this hypothesized association by comparing the SATNaPT between MVD responders and non-responders.

Materials and methods

At a single institution, 80 patients with a clinical diagnosis of trigeminal neuralgia, surgical intervention with MVD, and available adequate high-resolution T2 imaging were identified. SATNaPT was measured between the cisternal segment of the trigeminal nerve and its uppermost branch in the Meckel cave by a blinded observer. These data were evaluated for normality of distribution and compared between responders and non-responders to MVD as well as between affected and unaffected sides. Non-response to MVD was defined as persistent pain requiring continuous medication postoperatively or progression to secondary interventions.

Results

There were 43 (52.5 %) responders and 39 (47.5 %) non-responders to MVD. Two patients had bilateral disease for 82 affected sides and 78 unaffected sides. The mean SATNaPT among responders was 150.5° (SD: ±10.6°), which was not significantly different (p = 0.21) from the 153.1° (SD: ±8.0°) mean angle in non-responders. Mean SATNaPT was not significantly different (p = 0.10) between the affected (mean: 151.7°, SD: ±9.5°) and the unaffected (mean: 153.1°, SD: ±10.0°) sides.

Conclusions

Our study did not replicate the bimodal distribution of the SATNaPT in cTN patients. No statistically significant difference was noted in the SATNaPT between responders and non-responders to MVD or between symptomatic and asymptomatic sides.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Current Problems in Diagnostic Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

3.00

自引率

0.00%

发文量

113

审稿时长

46 days

期刊介绍： Current Problems in Diagnostic Radiology covers important and controversial topics in radiology. Each issue presents important viewpoints from leading radiologists. High-quality reproductions of radiographs, CT scans, MR images, and sonograms clearly depict what is being described in each article. Also included are valuable updates relevant to other areas of practice, such as medical-legal issues or archiving systems. With new multi-topic format and image-intensive style, Current Problems in Diagnostic Radiology offers an outstanding, time-saving investigation into current topics most relevant to radiologists.