急性发作全身性小脑共济失调1例报告。

IF 2.7 3区 医学 Q3 NEUROSCIENCES
Arthur Antônio Freire Alves, Arthur Felipe Barbosa Vasconcelos, Francisco Anderson de Sá Carvalho, Gilmar Leite Pessoa Filho, Ana Luísa Castelo Branco Gomes, Adriana M T Nepomuceno, Juliana Magalhães Leite, Rafael de Souza Andrade, João Alfredo M M Barros, Alex Tiburtino Meira
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引用次数: 0

摘要

在本病例报告中,我们描述了一位男性患者,年龄65岁,既往有动脉高血压和心房颤动,氯沙坦使用不规律,在神经急诊科入院前5.5小时出现突然发作的头晕、构音障碍和双侧共济失调。颅脑磁共振成像显示T2/FLAIR序列高信号,两小脑上动脉及左脑桥灌注区域弥散受限,与梗死相一致。颈动脉和脑动脉的CT血管造影显示一个血栓栓塞闭塞的底部动脉顶部。此外,根据心电图结果确认房颤。住院期间给予美托洛尔和达比加群治疗。出院时,患者在药物治疗下症状部分改善,并计划在30天后返回门诊。我们的病例强调了考虑小脑上动脉双侧区域缺血性中风的重要性,由于基底动脉顶部血栓,在出现全身性小脑共济失调的患者中,没有意识或视觉改变。临床试验编号不适用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Generalized Cerebellar Ataxia of Acute Onset: Case Report.

In this case report, we describe a male patient, aged 65 years, with previous arterial hypertension and atrial fibrillation, with irregular use of losartan, presenting with sudden onset of dizziness, dysarthria, and bilateral ataxia, 5.5 h before the admission to the neurological emergency department. The cranial magnetic resonance imaging revealed hyperintensities on T2/FLAIR sequences, and diffusion restriction in the territory irrigated by both superior cerebellar arteries, alongside with left pontine, compatible with infarct. The CT angiography of the cervical and cerebral arteries revealed a thromboembolic occlusion of the top of the basilar artery. Furthermore, atrial fibrillation was confirmed based on the results of the electrocardiogram. During hospitalization, the patient was treated with metoprolol and dabigatran. Upon discharge, the patient demonstrated a partial improvement in symptoms under medication and was scheduled to return to the outpatient clinic after 30 days. Our case highlights the importance of considering ischemic stroke in the territory of the cerebellar superior artery bilaterally, due to a top of basilar thrombus, in patients presenting with global cerebellar ataxia, with no consciousness or visual alteration. Clinical Trial Number Not applicable.

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来源期刊
Cerebellum
Cerebellum 医学-神经科学
CiteScore
6.40
自引率
14.30%
发文量
150
审稿时长
4-8 weeks
期刊介绍: Official publication of the Society for Research on the Cerebellum devoted to genetics of cerebellar ataxias, role of cerebellum in motor control and cognitive function, and amid an ageing population, diseases associated with cerebellar dysfunction. The Cerebellum is a central source for the latest developments in fundamental neurosciences including molecular and cellular biology; behavioural neurosciences and neurochemistry; genetics; fundamental and clinical neurophysiology; neurology and neuropathology; cognition and neuroimaging. The Cerebellum benefits neuroscientists in molecular and cellular biology; neurophysiologists; researchers in neurotransmission; neurologists; radiologists; paediatricians; neuropsychologists; students of neurology and psychiatry and others.
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