一项前瞻性临床研究:FASILA评分预测外伤性腹部和骨盆损伤的干预措施和结果的有效性。

IF 2.3 3区 医学 Q2 SURGERY
Ayman El-Menyar, Ahmed F Ramzee, Basel H Elmegabar, Mohammad Asim, Ruben Peralta, Vishwajit Verma, Husham Abdelrahman, Hisham Jogol, Muniba Afzal, Yasir Abdulrahman, Nuri Abdurraheim, Ahad Kanbar, Tariq Siddiqui, Sandro Rizoli, Hassan Al-Thani
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引用次数: 0

摘要

背景:FASILA评分是一个7分制,包括FAST(创伤超声集中评估)、休克指数和血清乳酸。我们的目的是在腹部和骨盆创伤患者中前瞻性地验证这一评分,以预测大量输血的需要、剖腹手术和住院死亡率。方法:这项前瞻性研究包括所有持续腹部和/或骨盆创伤的成年患者。排除了儿科患者、院前心脏骤停和严重头部损伤。结果:共400例患者(平均年龄36.3±12.7;男性90%;96%的人有钝性创伤)在2022年至2024年间登记。FASILA评分较高的患者(19.3%)剖腹探查率和放射干预率较高,输血量较多。他们也有更长的住院时间,更高的败血症率和死亡率(p = 0.001)。FASILA评分与休克指数(r = 0.75)、ISS (r = 0.38)、SOFA评分(r = 0.36)、腹部AIS (r = 0.27)、TRISS (r = -0.19)、RTS (r = -0.26)和纤维蛋白原水平(r = -0.12)显著相关。FASILA评分≥4分在预测是否需要手术方面具有高特异性(85.5%)和阴性预测值(80%)。在调整腹部AIS、ISS、SOFA评分和纤维蛋白原水平后,FASILA评分是输血的独立预测因子(优势比1.92,95% CI 1.43-2.58)。在预测MTP和手术干预方面,FASILA评分的AUROC曲线优于ABC评分和“单SI”。结论:高FASILA评分与输血量、手术干预和死亡率之间存在显著相关性,表明其在骨盆创伤早期风险分层中的作用。建议进行多中心研究,以提高不同人群和环境的外部有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Validation of the FASILA Score for Predicting Interventions and Outcomes in Traumatic Abdominal and Pelvic Injuries: A Prospective Clinical Study.

Background: The FASILA score is a 7-point scale comprising the FAST (focused assessment with sonography in trauma), shock index, and serum lactate. We aimed to validate this score prospectively in patients with abdominal and pelvic trauma to predict the need for massive blood transfusion, laparotomy, and inhospital mortality.

Methods: This prospective study included all adult patients who sustained abdominal and/or pelvic trauma. Pediatric patients, prehospital cardiac arrest, and severe head injury were excluded. Data were analyzed and compared with low (< 4) versus high (≥ 4) FASILA scores.

Results: A total of 400 patients (mean age 36.3 ± 12.7; 90% male; and 96% had blunt trauma) were enrolled between 2022 and 2024. Patients with higher FASILA scores (19.3%) had higher rates of exploratory laparotomy and radiological interventions and received more blood transfusions. They also had longer hospital stays, higher rates of sepsis, and mortality (p = 0.001). The FASILA scores significantly correlated with shock index (r = 0.75), ISS (r = 0.38), SOFA score (r = 0.36), and abdominal AIS (r = 0.27), TRISS (r = -0.19), RTS (r = -0.26), and fibrinogen levels (r = -0.12). A FASILA score ≥ 4 had a high specificity (85.5%) and negative predictive value (80%) for predicting the need for surgery. The FASILA score was an independent predictor of blood transfusion (odds ratio 1.92 and 95% CI 1.43-2.58) after adjusting for abdominal AIS, ISS, SOFA score, and fibrinogen level. AUROC curves were better for the FASILA score than ABC score and "SI alone" for the prediction of MTP and surgical interventions.

Conclusion: The significant association between high FASILA scores and blood transfusions, surgical interventions, and mortality indicates its usefulness in early risk stratification in abdominopelvic trauma. Multicenter studies are recommended to enhance external validity across diverse populations and settings.

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来源期刊
World Journal of Surgery
World Journal of Surgery 医学-外科
CiteScore
5.10
自引率
3.80%
发文量
460
审稿时长
3 months
期刊介绍: World Journal of Surgery is the official publication of the International Society of Surgery/Societe Internationale de Chirurgie (iss-sic.com). Under the editorship of Dr. Julie Ann Sosa, World Journal of Surgery provides an in-depth, international forum for the most authoritative information on major clinical problems in the fields of clinical and experimental surgery, surgical education, and socioeconomic aspects of surgical care. Contributions are reviewed and selected by a group of distinguished surgeons from across the world who make up the Editorial Board.
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