儿童骨显像定量生长板摄取参数与生长速度的关系。

IF 1.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Ki Jin Jung, Sun-Pyo Hong, Ik Dong Yoo, Sang Mi Lee, Jeong Won Lee
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引用次数: 0

摘要

目的:探讨儿童骨显像定量生长板摄取参数与生长速度的关系。方法:回顾性分析30例小儿患者(男21例,女9例;年龄范围3-15岁,接受平面骨显像。计算股骨前、后侧骨显像上最大生长板摄取与平均骨干摄取的比值(GPmax/D)和平均生长板摄取与平均骨干摄取的比值(GPmean/D)。共测量了8个GPmax/D参数和8个GPmean/D参数。评估了生长板吸收参数与年龄和生长速度(cm/年)的关系。结果:与生长速度相关分析显示,前路GPmax/D(前路图像上左右股骨间GPmax/D的数值平均值)在骨显像参数中具有最高的相关系数(0.409)(P = 0.034)。前路GPmax/D与年龄呈显著负相关(P = 0.042,相关系数为-0.373)。在对年龄和性别进行校正后预测生长速度的多元回归分析中,包含左侧GPmean/D(左侧股骨前后影像GPmean/D的几何平均值)的模型调整后的R2值最高(0.786),其次是前路GPmax/D(0.734)。结论:骨显像中股骨远端定量生长板摄取参数与生长速度有显著相关性。这些发现表明骨显像中生长板的摄取可能作为儿童生长的预测标志。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association of quantitative growth plate uptake parameters on bone scintigraphy with growth velocity in children.

Objective: The purpose of this study was to examine the association between quantitative growth plate uptake parameters in bone scintigraphy and growth velocity among children.

Methods: We conducted a retrospective analysis of 30 pediatric patients (21 male and nine female; age range, 3-15 years) who underwent planar bone scintigraphy. Ratios of maximum growth plate uptake to mean diaphyseal uptake (GPmax/D) and mean growth plate uptake to mean diaphyseal uptake (GPmean/D) were calculated for both femurs on anterior and posterior bone scintigraphy images. A total of eight GPmax/D parameters and eight GPmean/D parameters were measured. The relationships of growth plate uptake parameters with age and growth velocity (cm/year) were assessed.

Results: Correlation analysis with growth velocity revealed that the anterior GPmax/D (numerical mean of GPmax/D between the right and left femurs on an anterior image) exhibited the highest correlation coefficient (0.409) among the bone scintigraphy parameters (P = 0.034). The anterior GPmax/D also demonstrated a significant negative correlation with age (P = 0.042, correlation coefficient: -0.373). In a multiple regression analysis to predict growth velocity with adjusting for age and sex, the model that included left GPmean/D (geometric mean of GPmean/D between anterior and posterior images of the left femur) yielded the highest adjusted R2 value (0.786), followed by anterior GPmax/D (0.734).

Conclusion: Quantitative growth plate uptake parameters on the distal femur in bone scintigraphy are significantly associated with growth velocity. These findings suggest that growth plate uptake in bone scintigraphy could potentially serve as a predictive marker of growth in children.

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来源期刊
CiteScore
2.20
自引率
6.70%
发文量
212
审稿时长
3-8 weeks
期刊介绍: Nuclear Medicine Communications, the official journal of the British Nuclear Medicine Society, is a rapid communications journal covering nuclear medicine and molecular imaging with radionuclides, and the basic supporting sciences. As well as clinical research and commentary, manuscripts describing research on preclinical and basic sciences (radiochemistry, radiopharmacy, radiobiology, radiopharmacology, medical physics, computing and engineering, and technical and nursing professions involved in delivering nuclear medicine services) are welcomed, as the journal is intended to be of interest internationally to all members of the many medical and non-medical disciplines involved in nuclear medicine. In addition to papers reporting original studies, frankly written editorials and topical reviews are a regular feature of the journal.
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