应用吲哚菁绿荧光成像技术在腹腔镜直肠癌手术中的应用:1例报告。

IF 2 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY
Journal of gastrointestinal oncology Pub Date : 2025-04-30 Epub Date: 2025-04-27 DOI:10.21037/jgo-2025-245
Youqiang Liu, Songjie Li, Zhenya Zhang, Chenhui Li, Pengwei Li, Hongqing Ma, Guiying Wang
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引用次数: 0

摘要

结直肠癌是临床上常见的高发病率、高死亡率的恶性肿瘤。手术仍然是结直肠癌的首选治疗方法。腹腔镜手术因其手术创伤小、术后恢复快等优点,比开放手术应用更广泛。然而,吻合口漏、出血、肠梗阻、腹腔内感染等并发症仍可发生,延长住院时间,影响患者康复。其中吻合口漏是严重的并发症,严重影响患者术后恢复。吲哚菁绿(ICG)荧光成像(FI)结合4K腹腔镜已成为提高手术质量的一种有前途的方法。ICG是一种水溶性三碳菁染料,毒性低,与血浆蛋白结合亲和力强,半衰期短,适合术中使用。它可以实现血流的实时可视化,便于转移的检测、吻合口灌注的评估和精确的淋巴结清扫。这项技术已被证明可以提高阳性淋巴结的检出率,减少术后并发症。我们报告一例66岁男性直肠腺癌患者接受荧光腹腔镜辅助直肠癌根治术(Dixon手术)。患者于术后第1天(POD)开始下床,第2天开始顺利排气和排便,第6天取出盆腔引流管后出院。本文重点介绍ICG-FI腹腔镜技术在直肠癌手术中的应用技术及优势,为其临床应用提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Using an indocyanine green fluorescent imaging technique for laparoscopic rectal cancer surgery: a case report.

Colorectal cancer is a clinically common malignancy with high incidence and mortality rates. Surgery remains the preferred treatment option for colorectal cancer. Laparoscopic surgery is more widely used than open surgery due to its advantages of reduced surgical trauma and faster postoperative recovery. However, complications such as anastomotic leakage, bleeding, intestinal obstruction, and intra-abdominal infections can still occur, prolonging hospital stays and impairing patient recovery. In particular, anastomotic leakage is a severe complication that significantly affects the postoperative recovery of patients. Indocyanine green (ICG) fluorescence imaging (FI) combined with 4K laparoscopy has emerged as a promising approach for enhancing surgical quality. ICG is a water-soluble tricarbocyanine dye with low toxicity, a strong binding affinity to plasma proteins, and a short half-life, making it suitable for intraoperative use. It enables the real-time visualization of blood flow, which facilitates the detection of metastases, the assessment of anastomotic perfusion, and precise lymph node dissection. This technology has been shown to improve the detection of positive lymph nodes and reduce postoperative complications. We report the case of a 66-year-old male patient with rectal adenocarcinoma who underwent fluorescent laparoscopy-assisted radical resection of rectal cancer (Dixon procedure). The patient initiated ambulation on postoperative day (POD) 1, followed by successful flatus passage and bowel movement initiation on POD 2, and was discharged on POD 6 after the removal of the pelvic drain. This article highlights the application techniques and advantages of ICG-FI laparoscopic technology in rectal cancer surgery to provide a reference for its clinical application.

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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
171
期刊介绍: ournal of Gastrointestinal Oncology (Print ISSN 2078-6891; Online ISSN 2219-679X; J Gastrointest Oncol; JGO), the official journal of Society for Gastrointestinal Oncology (SGO), is an open-access, international peer-reviewed journal. It is published quarterly (Sep. 2010- Dec. 2013), bimonthly (Feb. 2014 -) and openly distributed worldwide. JGO publishes manuscripts that focus on updated and practical information about diagnosis, prevention and clinical investigations of gastrointestinal cancer treatment. Specific areas of interest include, but not limited to, multimodality therapy, markers, imaging and tumor biology.
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