{"title":"胚胎生物电流与分化波有关系吗?","authors":"Richard Gordon","doi":"10.1016/j.biosystems.2025.105483","DOIUrl":null,"url":null,"abstract":"<div><div>Differentiation waves usually spread in embryonic epithelia until they reach boundaries whose stopping power has been unexplained. Bioelectricity in embryos has two ranges: cell-to-cell and long-range. It is postulated here that the long-range component somehow alters gap junctions and/or intermediate filaments, creating the boundaries for the trajectories of differentiation waves. A combined EIT (Electric Impedance Tomography)/visual microscope is proposed to investigate this proposed correlation.</div></div>","PeriodicalId":50730,"journal":{"name":"Biosystems","volume":"253 ","pages":"Article 105483"},"PeriodicalIF":2.0000,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Is there a relationship between embryonic bioelectric currents and differentiation waves?\",\"authors\":\"Richard Gordon\",\"doi\":\"10.1016/j.biosystems.2025.105483\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Differentiation waves usually spread in embryonic epithelia until they reach boundaries whose stopping power has been unexplained. Bioelectricity in embryos has two ranges: cell-to-cell and long-range. It is postulated here that the long-range component somehow alters gap junctions and/or intermediate filaments, creating the boundaries for the trajectories of differentiation waves. A combined EIT (Electric Impedance Tomography)/visual microscope is proposed to investigate this proposed correlation.</div></div>\",\"PeriodicalId\":50730,\"journal\":{\"name\":\"Biosystems\",\"volume\":\"253 \",\"pages\":\"Article 105483\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-05-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biosystems\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0303264725000930\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biosystems","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0303264725000930","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOLOGY","Score":null,"Total":0}
Is there a relationship between embryonic bioelectric currents and differentiation waves?
Differentiation waves usually spread in embryonic epithelia until they reach boundaries whose stopping power has been unexplained. Bioelectricity in embryos has two ranges: cell-to-cell and long-range. It is postulated here that the long-range component somehow alters gap junctions and/or intermediate filaments, creating the boundaries for the trajectories of differentiation waves. A combined EIT (Electric Impedance Tomography)/visual microscope is proposed to investigate this proposed correlation.
期刊介绍:
BioSystems encourages experimental, computational, and theoretical articles that link biology, evolutionary thinking, and the information processing sciences. The link areas form a circle that encompasses the fundamental nature of biological information processing, computational modeling of complex biological systems, evolutionary models of computation, the application of biological principles to the design of novel computing systems, and the use of biomolecular materials to synthesize artificial systems that capture essential principles of natural biological information processing.