[肺移植适应症-自上次ISHLT建议以来的更新]。

IF 0.5 4区 医学 Q4 SURGERY
Zentralblatt fur Chirurgie Pub Date : 2025-06-01 Epub Date: 2025-05-15 DOI:10.1055/a-2563-3691
Zsofia Kovacs, Alberto Benazzo, Peter Jaksch
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引用次数: 0

摘要

自20世纪60年代首次成功手术以来,肺移植不断发展。国际心肺移植学会(ISHLT)目前的指南强调越来越个性化的患者评估,除了潜在的肺部疾病外,还考虑合并症、虚弱、年龄和社会方面等因素。肺移植适应症的扩大反映在精细的风险评估中,特别是晚期慢性阻塞性肺疾病(COPD)、特发性肺纤维化(IPF)和肺动脉高压(PAH)患者。此外,有癌症病史和感染艾滋病毒或耐多药生物的患者的标准也变得更加灵活,从而导致更具包容性的移植政策。一个关键的重点是早期移植咨询,使患者有机会在急性恶化之前进行移植。这些更新的指南旨在通过差异化和风险调整决策,最大限度地提高移植患者的生存率和生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Indications for Lung Transplantation - Updates Since the Last ISHLT Recommendations].

Lung transplantation has evolved continuously since its first successful procedures in the 1960 s. The current guidelines from the International Society for Heart and Lung Transplantation (ISHLT) emphasise increasingly individualised patient assessment, which, in addition to the underlying lung disease, considers factors such as comorbidities, frailty, age, and social aspects. The expanded indications for lung transplantation are reflected in the refined risk assessment, which particularly includes patients with advanced chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), and pulmonary arterial hypertension (PAH). Furthermore, the criteria for patients with a history of cancer and those with infections such as HIV or multidrug-resistant organisms have been made more flexible, leading to a more inclusive transplantation policy. A key focus is on early transplant counselling, allowing patients the opportunity for transplantation before they develop acute exacerbations. These updated guidelines aim to maximise both the survival rates and the quality of life of transplant patients, through differentiated and risk-adjusted decision-making.

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来源期刊
CiteScore
1.00
自引率
14.30%
发文量
116
审稿时长
6-12 weeks
期刊介绍: Konzentriertes Fachwissen aus Forschung und Praxis Das Zentralblatt für Chirurgie – alle Neuigkeiten aus der Allgemeinen, Viszeral-, Thorax- und Gefäßchirurgie.
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