Ifrah Iqbal, Hamood Ur Rehman, Muhammad Shoaib Saleem, Abdul Malik Sultan, Hameed Ashraf
{"title":"微管作为细胞和神经元功能中的电通道的非线性动力学:孤子解和调制不稳定性","authors":"Ifrah Iqbal, Hamood Ur Rehman, Muhammad Shoaib Saleem, Abdul Malik Sultan, Hameed Ashraf","doi":"10.1007/s13538-025-01773-2","DOIUrl":null,"url":null,"abstract":"<div><p>Microtubules are fundamental to the cellular cytoskeleton, participating in diverse functions like cell division and intracellular transport facilitated by motor proteins such as dynein and kinesin. Moreover, they have critical roles in advanced neuronal activities, including consciousness and memory. This study explores the specific conditions that allow microtubules to operate as nonlinear electrical conduits for ion flow along their structures. By modeling them as nonlinear resistive, inductive, and capacitive (RLC) transmission lines, we employ the generalized Riccati equation mapping method to derive solutions for these dynamics. This study also gives a comprehensive literature review for the modeled equation and emphasizes the uniqueness of this interdisciplinary approach. Comparative analyses of specific outcomes are presented, with graphical illustrations to clarify the physical implications. Modulation instability (MI) analysis has been incorporated to investigate the frequency behavior of <span>\\( w(a) \\)</span> under varying parameters. By applying nonlinear engineering principles sheds new light on microtubule functionality in neuronal and cellular contexts, laying a foundation for new developments in bioengineering and nanobioscience.</p></div>","PeriodicalId":499,"journal":{"name":"Brazilian Journal of Physics","volume":"55 4","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nonlinear Dynamics of Microtubules as Electrical Conduits in Cellular and Neuronal Functions: Soliton Solutions and Modulation Instability\",\"authors\":\"Ifrah Iqbal, Hamood Ur Rehman, Muhammad Shoaib Saleem, Abdul Malik Sultan, Hameed Ashraf\",\"doi\":\"10.1007/s13538-025-01773-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Microtubules are fundamental to the cellular cytoskeleton, participating in diverse functions like cell division and intracellular transport facilitated by motor proteins such as dynein and kinesin. Moreover, they have critical roles in advanced neuronal activities, including consciousness and memory. This study explores the specific conditions that allow microtubules to operate as nonlinear electrical conduits for ion flow along their structures. By modeling them as nonlinear resistive, inductive, and capacitive (RLC) transmission lines, we employ the generalized Riccati equation mapping method to derive solutions for these dynamics. This study also gives a comprehensive literature review for the modeled equation and emphasizes the uniqueness of this interdisciplinary approach. Comparative analyses of specific outcomes are presented, with graphical illustrations to clarify the physical implications. Modulation instability (MI) analysis has been incorporated to investigate the frequency behavior of <span>\\\\( w(a) \\\\)</span> under varying parameters. By applying nonlinear engineering principles sheds new light on microtubule functionality in neuronal and cellular contexts, laying a foundation for new developments in bioengineering and nanobioscience.</p></div>\",\"PeriodicalId\":499,\"journal\":{\"name\":\"Brazilian Journal of Physics\",\"volume\":\"55 4\",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-05-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brazilian Journal of Physics\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s13538-025-01773-2\",\"RegionNum\":4,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHYSICS, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Journal of Physics","FirstCategoryId":"101","ListUrlMain":"https://link.springer.com/article/10.1007/s13538-025-01773-2","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSICS, MULTIDISCIPLINARY","Score":null,"Total":0}
Nonlinear Dynamics of Microtubules as Electrical Conduits in Cellular and Neuronal Functions: Soliton Solutions and Modulation Instability
Microtubules are fundamental to the cellular cytoskeleton, participating in diverse functions like cell division and intracellular transport facilitated by motor proteins such as dynein and kinesin. Moreover, they have critical roles in advanced neuronal activities, including consciousness and memory. This study explores the specific conditions that allow microtubules to operate as nonlinear electrical conduits for ion flow along their structures. By modeling them as nonlinear resistive, inductive, and capacitive (RLC) transmission lines, we employ the generalized Riccati equation mapping method to derive solutions for these dynamics. This study also gives a comprehensive literature review for the modeled equation and emphasizes the uniqueness of this interdisciplinary approach. Comparative analyses of specific outcomes are presented, with graphical illustrations to clarify the physical implications. Modulation instability (MI) analysis has been incorporated to investigate the frequency behavior of \( w(a) \) under varying parameters. By applying nonlinear engineering principles sheds new light on microtubule functionality in neuronal and cellular contexts, laying a foundation for new developments in bioengineering and nanobioscience.
期刊介绍:
The Brazilian Journal of Physics is a peer-reviewed international journal published by the Brazilian Physical Society (SBF). The journal publishes new and original research results from all areas of physics, obtained in Brazil and from anywhere else in the world. Contents include theoretical, practical and experimental papers as well as high-quality review papers. Submissions should follow the generally accepted structure for journal articles with basic elements: title, abstract, introduction, results, conclusions, and references.