靶向心脏修复的可吸入外泌体。

IF 4.8
Extracellular vesicles and circulating nucleic acids Pub Date : 2025-03-25 eCollection Date: 2025-01-01 DOI:10.20517/evcna.2024.81
Ajit Magadum
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引用次数: 0

摘要

最近的一项研究介绍了干细胞来源的外泌体雾化疗法(SCENT),这是一种新颖的、无创的策略,通过吸入肺球体细胞来源的外泌体来促进心肌梗死后的心脏修复。这种方法改善了心脏功能,减少了损伤,并在小型和大型动物模型中展示了转化潜力,为无细胞、可吸入的再生疗法提供了一条有前途的途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inhalable exosomes to target cardiac repair.

A recent study introduces Stem Cell-derived Exosome Nebulization Therapy (SCENT), a novel, non-invasive strategy that delivers lung spheroid cell-derived exosomes via inhalation to promote cardiac repair after myocardial infarction. This approach improves cardiac function, reduces injury, and demonstrates translational potential in both small and large animal models, offering a promising avenue for cell-free, inhalable regenerative therapies.

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