儿童动脉瘤性骨囊肿血浆内脂素浓度降低:一项初步研究。

Sait A Ulus, Emin Özkul
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引用次数: 0

摘要

目的:本研究是一项前瞻性研究,比较动脉瘤性骨囊肿(ABC)患者与健康人的视觉素值。方法:本研究包括20例诊断为ABC的患者(第一组)和30例健康患者(第二组)。记录并评估所有患者的年龄、性别、囊肿大小和visfatin值。结果:共纳入50例患者,其中组1 20例,组2 30例。组1的平均年龄为13.80±3.98岁,组2的平均年龄为14.67±4.24岁,组间比较差异无统计学意义(p < 0.05)。第1组中男性占60%,第2组中男性占53%。记录囊肿面积为1171 (512-2310)mm2。visfatin值1组为10.70±5.91 ng/mL, 2组为15.23±5.86 ng/mL。ABC组visfatin值低于对照组,差异有统计学意义(p < 0.05)。囊肿面积与内脏脂肪素无相关性(p < 0.05)。结论:我们的研究发现,与健康对照相比,ABC患者的内脏脂肪素水平明显较低,这表明它有可能作为一种诊断性生物标志物。ROC分析显示诊断能力较好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Decreased plasma visfatin concentrations in pediatric aneurysmal bone cyst: a pilot study.

Objective: This is a prospective study and visfatin values of patients with aneurysmal bone cysts (ABC) were compared with those of healthy individuals.

Method: This study consists of 20 patients diagnosed with ABC (Group 1) and 30 healthy patients (Group 2). Age, gender, cyst sizes, and visfatin values of all patients were recorded and evaluated.

Results: A total of 50 patients, 20 from Group 1 and 30 from Group 2, were included in our study. The mean age was 13.80 ± 3.98 years in Group 1 and 14.67 ± 4.24 years in Group 2, and no statistically significant difference was found between the groups (p > 0.05). While 60% of the patients in Group 1 were male, in Group 2, 53% of the patients were male. Cyst area was recorded as 1171 (512-2310) mm2. The visfatin value was 10.70 ± 5.91 ng/mL in Group 1 and 15.23 ± 5.86 ng/mL in Group 2. The visfatin value in the ABC group was found to be statistically significantly lower than the control group (p < 0.05). No correlation was found between cyst area and visfatin (p > 0.05).

Conclusion: Our study found that visfatin levels are significantly lower in patients with ABC s compared to healthy controls, suggesting its potential as a diagnostic biomarker. The ROC analysis showed a good diagnostic ability.

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