Bruna Dos Santos Costa, Denise Lautenschleger Fischer, Fabiana Ávila Lourenço de Lima, Mariana Severo da Costa, Fernanda Maria Vendrusculo, Márcio Vinícius Fagundes Donadio
{"title":"囊性纤维化儿童1分钟坐立试验：心肺反应及其与有氧适能、营养状况、肺功能和股四头肌力量的相关性","authors":"Bruna Dos Santos Costa, Denise Lautenschleger Fischer, Fabiana Ávila Lourenço de Lima, Mariana Severo da Costa, Fernanda Maria Vendrusculo, Márcio Vinícius Fagundes Donadio","doi":"10.1080/09593985.2025.2494114","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To characterize physiological responses to a 1-minute sit-to-stand test (STS) and assess correlations with cardiopulmonary exercise test (CPET) variables, nutritional status, pulmonary function, and quadriceps muscle strength in cystic fibrosis (CF) patients.</p><p><strong>Methods: </strong>Subjects aged 6-18 years with a genetic diagnosis of CF were enrolled in this cross-sectional study. After collecting demographic, anthropometric, and clinical data the following tests were performed: pulmonary function (spirometry), aerobic fitness (CPET), STS, and isometric quadriceps muscle strength (hand-held dynamometry). Data collection was performed on the same day.</p><p><strong>Results: </strong>The study sample comprised 17 children (9.8 ± 1.6 years) and adolescents (13.7 ± 1.5 years) with a mean forced expiratory volume in one second (FEV<sub>1</sub>) of - 0.80 ± 1.61 (z-score). In the CPET, peak exercise oxygen consumption (VO<sub>2</sub>peak) was 35.1 ± 4.2 mL.kg<sup>-1</sup>.min<sup>-1</sup>, while in the STS mean number of repetitions was 32.5 ± 6.2 and total work (repetitions × body mass) was 1326.9 ± 379.6. At peak exercise, CPET elicited higher heart rate (<i>p</i> = .001) and subjective sensation of dyspnea (<i>p</i> = .001) compared to STS, though no significant differences were observed in peripheral oxygen saturation. Moderate and significant correlations were identified between total workload (CPET) and repetitions adjusted for body weight (<i>r</i> = 0.684; <i>p</i> = .002) and between STS repetitions and muscle strength corrected for body weight (<i>r</i> = 0.531; <i>p</i> = .034). No significant correlations were found with nutritional status (BMI), pulmonary function (FEV<sub>1</sub>), or other aerobic fitness variables (VO<sub>2</sub> at ventilatory threshold or VO<sub>2</sub>peak).</p><p><strong>Conclusion: </strong>In children and adolescents with CF, compared to CPET, the STS test elicits a submaximal cardiorespiratory response that is mostly dependent on quadriceps muscle strength.</p>","PeriodicalId":48699,"journal":{"name":"Physiotherapy Theory and Practice","volume":" ","pages":"2067-2074"},"PeriodicalIF":1.5000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The 1-minute sit-to-stand test in children with cystic fibrosis: cardiorespiratory responses and correlations with aerobic fitness, nutritional status, pulmonary function, and quadriceps strength.\",\"authors\":\"Bruna Dos Santos Costa, Denise Lautenschleger Fischer, Fabiana Ávila Lourenço de Lima, Mariana Severo da Costa, Fernanda Maria Vendrusculo, Márcio Vinícius Fagundes Donadio\",\"doi\":\"10.1080/09593985.2025.2494114\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To characterize physiological responses to a 1-minute sit-to-stand test (STS) and assess correlations with cardiopulmonary exercise test (CPET) variables, nutritional status, pulmonary function, and quadriceps muscle strength in cystic fibrosis (CF) patients.</p><p><strong>Methods: </strong>Subjects aged 6-18 years with a genetic diagnosis of CF were enrolled in this cross-sectional study. After collecting demographic, anthropometric, and clinical data the following tests were performed: pulmonary function (spirometry), aerobic fitness (CPET), STS, and isometric quadriceps muscle strength (hand-held dynamometry). Data collection was performed on the same day.</p><p><strong>Results: </strong>The study sample comprised 17 children (9.8 ± 1.6 years) and adolescents (13.7 ± 1.5 years) with a mean forced expiratory volume in one second (FEV<sub>1</sub>) of - 0.80 ± 1.61 (z-score). In the CPET, peak exercise oxygen consumption (VO<sub>2</sub>peak) was 35.1 ± 4.2 mL.kg<sup>-1</sup>.min<sup>-1</sup>, while in the STS mean number of repetitions was 32.5 ± 6.2 and total work (repetitions × body mass) was 1326.9 ± 379.6. At peak exercise, CPET elicited higher heart rate (<i>p</i> = .001) and subjective sensation of dyspnea (<i>p</i> = .001) compared to STS, though no significant differences were observed in peripheral oxygen saturation. Moderate and significant correlations were identified between total workload (CPET) and repetitions adjusted for body weight (<i>r</i> = 0.684; <i>p</i> = .002) and between STS repetitions and muscle strength corrected for body weight (<i>r</i> = 0.531; <i>p</i> = .034). No significant correlations were found with nutritional status (BMI), pulmonary function (FEV<sub>1</sub>), or other aerobic fitness variables (VO<sub>2</sub> at ventilatory threshold or VO<sub>2</sub>peak).</p><p><strong>Conclusion: </strong>In children and adolescents with CF, compared to CPET, the STS test elicits a submaximal cardiorespiratory response that is mostly dependent on quadriceps muscle strength.</p>\",\"PeriodicalId\":48699,\"journal\":{\"name\":\"Physiotherapy Theory and Practice\",\"volume\":\" \",\"pages\":\"2067-2074\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physiotherapy Theory and Practice\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/09593985.2025.2494114\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/22 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"REHABILITATION\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physiotherapy Theory and Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09593985.2025.2494114","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/22 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"REHABILITATION","Score":null,"Total":0}
The 1-minute sit-to-stand test in children with cystic fibrosis: cardiorespiratory responses and correlations with aerobic fitness, nutritional status, pulmonary function, and quadriceps strength.
Objective: To characterize physiological responses to a 1-minute sit-to-stand test (STS) and assess correlations with cardiopulmonary exercise test (CPET) variables, nutritional status, pulmonary function, and quadriceps muscle strength in cystic fibrosis (CF) patients.
Methods: Subjects aged 6-18 years with a genetic diagnosis of CF were enrolled in this cross-sectional study. After collecting demographic, anthropometric, and clinical data the following tests were performed: pulmonary function (spirometry), aerobic fitness (CPET), STS, and isometric quadriceps muscle strength (hand-held dynamometry). Data collection was performed on the same day.
Results: The study sample comprised 17 children (9.8 ± 1.6 years) and adolescents (13.7 ± 1.5 years) with a mean forced expiratory volume in one second (FEV1) of - 0.80 ± 1.61 (z-score). In the CPET, peak exercise oxygen consumption (VO2peak) was 35.1 ± 4.2 mL.kg-1.min-1, while in the STS mean number of repetitions was 32.5 ± 6.2 and total work (repetitions × body mass) was 1326.9 ± 379.6. At peak exercise, CPET elicited higher heart rate (p = .001) and subjective sensation of dyspnea (p = .001) compared to STS, though no significant differences were observed in peripheral oxygen saturation. Moderate and significant correlations were identified between total workload (CPET) and repetitions adjusted for body weight (r = 0.684; p = .002) and between STS repetitions and muscle strength corrected for body weight (r = 0.531; p = .034). No significant correlations were found with nutritional status (BMI), pulmonary function (FEV1), or other aerobic fitness variables (VO2 at ventilatory threshold or VO2peak).
Conclusion: In children and adolescents with CF, compared to CPET, the STS test elicits a submaximal cardiorespiratory response that is mostly dependent on quadriceps muscle strength.
期刊介绍：
The aim of Physiotherapy Theory and Practice is to provide an international, peer-reviewed forum for the publication, dissemination, and discussion of recent developments and current research in physiotherapy/physical therapy. The journal accepts original quantitative and qualitative research reports, theoretical papers, systematic literature reviews, clinical case reports, and technical clinical notes. Physiotherapy Theory and Practice; promotes post-basic education through reports, reviews, and updates on all aspects of physiotherapy and specialties relating to clinical physiotherapy.
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