使用开源大型语言模型自动合成患者的整个影像病历:可行性研究。

IF 2.2 4区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Fabio Mattiussi, Francesco Magoga, Simone Schiaffino, Vittorio Ferrari, Ermidio Rezzonico, Filippo Del Grande, Stefania Rizzo
{"title":"使用开源大型语言模型自动合成患者的整个影像病历:可行性研究。","authors":"Fabio Mattiussi, Francesco Magoga, Simone Schiaffino, Vittorio Ferrari, Ermidio Rezzonico, Filippo Del Grande, Stefania Rizzo","doi":"10.3390/tomography11040047","DOIUrl":null,"url":null,"abstract":"<p><strong>Background/objectives: </strong>Reviewing the entire history of imaging exams of a single patient's records is an essential step in clinical practice, but it is time and resource consuming, with potential negative effects on workflow and on the quality of medical decisions. The main objective of this study was to evaluate the applicability of three open-source large language models (LLMs) for the automatic generation of concise summaries of patient's imaging records. Secondary objectives were to assess correlations among the LLMs and to evaluate the length reduction provided by each model.</p><p><strong>Methods: </strong>Three state-of-the-art open-source large language models were selected: Llama 3.2 11B, Mistral 7B, and Falcon 7B. Each model was given a set of radiology reports. The summaries produced by the models were evaluated by two experienced radiologists and one experienced clinical physician using standardized metrics.</p><p><strong>Results: </strong>A variable number of radiological reports (n = 12-56) from four patients were selected and evaluated. The summaries generated by the three LLM showed a good level of accuracy compared with the information contained in the original reports, with positive ratings on both clinical relevance and ease of reference. According to the experts' evaluations, the use of the summaries generated by LLMs could help to reduce the time spent on reviewing the previous imaging examinations performed, preserving the quality of clinical data.</p><p><strong>Conclusions: </strong>Our results suggest that LLMs are able to generate summaries of the imaging history of patients, and these summaries could improve radiology workflow making it easier to manage large volumes of reports.</p>","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"11 4","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12031312/pdf/","citationCount":"0","resultStr":"{\"title\":\"Use of Open-Source Large Language Models for Automatic Synthesis of the Entire Imaging Medical Records of Patients: A Feasibility Study.\",\"authors\":\"Fabio Mattiussi, Francesco Magoga, Simone Schiaffino, Vittorio Ferrari, Ermidio Rezzonico, Filippo Del Grande, Stefania Rizzo\",\"doi\":\"10.3390/tomography11040047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background/objectives: </strong>Reviewing the entire history of imaging exams of a single patient's records is an essential step in clinical practice, but it is time and resource consuming, with potential negative effects on workflow and on the quality of medical decisions. The main objective of this study was to evaluate the applicability of three open-source large language models (LLMs) for the automatic generation of concise summaries of patient's imaging records. Secondary objectives were to assess correlations among the LLMs and to evaluate the length reduction provided by each model.</p><p><strong>Methods: </strong>Three state-of-the-art open-source large language models were selected: Llama 3.2 11B, Mistral 7B, and Falcon 7B. Each model was given a set of radiology reports. The summaries produced by the models were evaluated by two experienced radiologists and one experienced clinical physician using standardized metrics.</p><p><strong>Results: </strong>A variable number of radiological reports (n = 12-56) from four patients were selected and evaluated. The summaries generated by the three LLM showed a good level of accuracy compared with the information contained in the original reports, with positive ratings on both clinical relevance and ease of reference. According to the experts' evaluations, the use of the summaries generated by LLMs could help to reduce the time spent on reviewing the previous imaging examinations performed, preserving the quality of clinical data.</p><p><strong>Conclusions: </strong>Our results suggest that LLMs are able to generate summaries of the imaging history of patients, and these summaries could improve radiology workflow making it easier to manage large volumes of reports.</p>\",\"PeriodicalId\":51330,\"journal\":{\"name\":\"Tomography\",\"volume\":\"11 4\",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12031312/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tomography\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/tomography11040047\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tomography","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/tomography11040047","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

摘要

背景/目的:回顾单个患者影像检查的整个历史记录是临床实践中必不可少的一步,但它既费时又耗资源,对工作流程和医疗决策质量有潜在的负面影响。本研究的主要目的是评估三种开源大型语言模型(llm)在自动生成患者影像记录简明摘要方面的适用性。次要目标是评估llm之间的相关性,并评估每个模型提供的长度减少。方法:选择三种最先进的开源大型语言模型:Llama 3.2 11B、Mistral 7B和Falcon 7B。每个模型都有一组放射学报告。模型生成的摘要由两名经验丰富的放射科医生和一名经验丰富的临床医生使用标准化指标进行评估。结果:选取4例患者的不同数量的放射学报告(n = 12-56)并进行评估。与原始报告中包含的信息相比,三位LLM生成的摘要显示出良好的准确性,在临床相关性和参考便利性方面都获得了积极的评价。根据专家的评估,使用法学硕士生成的摘要可以帮助减少回顾以前进行的影像学检查所花费的时间,保持临床数据的质量。结论:我们的研究结果表明,llm能够生成患者成像历史的摘要,这些摘要可以改善放射学工作流程,使其更容易管理大量报告。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of Open-Source Large Language Models for Automatic Synthesis of the Entire Imaging Medical Records of Patients: A Feasibility Study.

Background/objectives: Reviewing the entire history of imaging exams of a single patient's records is an essential step in clinical practice, but it is time and resource consuming, with potential negative effects on workflow and on the quality of medical decisions. The main objective of this study was to evaluate the applicability of three open-source large language models (LLMs) for the automatic generation of concise summaries of patient's imaging records. Secondary objectives were to assess correlations among the LLMs and to evaluate the length reduction provided by each model.

Methods: Three state-of-the-art open-source large language models were selected: Llama 3.2 11B, Mistral 7B, and Falcon 7B. Each model was given a set of radiology reports. The summaries produced by the models were evaluated by two experienced radiologists and one experienced clinical physician using standardized metrics.

Results: A variable number of radiological reports (n = 12-56) from four patients were selected and evaluated. The summaries generated by the three LLM showed a good level of accuracy compared with the information contained in the original reports, with positive ratings on both clinical relevance and ease of reference. According to the experts' evaluations, the use of the summaries generated by LLMs could help to reduce the time spent on reviewing the previous imaging examinations performed, preserving the quality of clinical data.

Conclusions: Our results suggest that LLMs are able to generate summaries of the imaging history of patients, and these summaries could improve radiology workflow making it easier to manage large volumes of reports.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Tomography
Tomography Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
2.70
自引率
10.50%
发文量
222
期刊介绍: TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine. Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians. Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信