Fabio Mattiussi, Francesco Magoga, Simone Schiaffino, Vittorio Ferrari, Ermidio Rezzonico, Filippo Del Grande, Stefania Rizzo
{"title":"使用开源大型语言模型自动合成患者的整个影像病历:可行性研究。","authors":"Fabio Mattiussi, Francesco Magoga, Simone Schiaffino, Vittorio Ferrari, Ermidio Rezzonico, Filippo Del Grande, Stefania Rizzo","doi":"10.3390/tomography11040047","DOIUrl":null,"url":null,"abstract":"<p><strong>Background/objectives: </strong>Reviewing the entire history of imaging exams of a single patient's records is an essential step in clinical practice, but it is time and resource consuming, with potential negative effects on workflow and on the quality of medical decisions. The main objective of this study was to evaluate the applicability of three open-source large language models (LLMs) for the automatic generation of concise summaries of patient's imaging records. Secondary objectives were to assess correlations among the LLMs and to evaluate the length reduction provided by each model.</p><p><strong>Methods: </strong>Three state-of-the-art open-source large language models were selected: Llama 3.2 11B, Mistral 7B, and Falcon 7B. Each model was given a set of radiology reports. The summaries produced by the models were evaluated by two experienced radiologists and one experienced clinical physician using standardized metrics.</p><p><strong>Results: </strong>A variable number of radiological reports (n = 12-56) from four patients were selected and evaluated. The summaries generated by the three LLM showed a good level of accuracy compared with the information contained in the original reports, with positive ratings on both clinical relevance and ease of reference. According to the experts' evaluations, the use of the summaries generated by LLMs could help to reduce the time spent on reviewing the previous imaging examinations performed, preserving the quality of clinical data.</p><p><strong>Conclusions: </strong>Our results suggest that LLMs are able to generate summaries of the imaging history of patients, and these summaries could improve radiology workflow making it easier to manage large volumes of reports.</p>","PeriodicalId":51330,"journal":{"name":"Tomography","volume":"11 4","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12031312/pdf/","citationCount":"0","resultStr":"{\"title\":\"Use of Open-Source Large Language Models for Automatic Synthesis of the Entire Imaging Medical Records of Patients: A Feasibility Study.\",\"authors\":\"Fabio Mattiussi, Francesco Magoga, Simone Schiaffino, Vittorio Ferrari, Ermidio Rezzonico, Filippo Del Grande, Stefania Rizzo\",\"doi\":\"10.3390/tomography11040047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background/objectives: </strong>Reviewing the entire history of imaging exams of a single patient's records is an essential step in clinical practice, but it is time and resource consuming, with potential negative effects on workflow and on the quality of medical decisions. The main objective of this study was to evaluate the applicability of three open-source large language models (LLMs) for the automatic generation of concise summaries of patient's imaging records. Secondary objectives were to assess correlations among the LLMs and to evaluate the length reduction provided by each model.</p><p><strong>Methods: </strong>Three state-of-the-art open-source large language models were selected: Llama 3.2 11B, Mistral 7B, and Falcon 7B. Each model was given a set of radiology reports. The summaries produced by the models were evaluated by two experienced radiologists and one experienced clinical physician using standardized metrics.</p><p><strong>Results: </strong>A variable number of radiological reports (n = 12-56) from four patients were selected and evaluated. The summaries generated by the three LLM showed a good level of accuracy compared with the information contained in the original reports, with positive ratings on both clinical relevance and ease of reference. According to the experts' evaluations, the use of the summaries generated by LLMs could help to reduce the time spent on reviewing the previous imaging examinations performed, preserving the quality of clinical data.</p><p><strong>Conclusions: </strong>Our results suggest that LLMs are able to generate summaries of the imaging history of patients, and these summaries could improve radiology workflow making it easier to manage large volumes of reports.</p>\",\"PeriodicalId\":51330,\"journal\":{\"name\":\"Tomography\",\"volume\":\"11 4\",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12031312/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tomography\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/tomography11040047\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tomography","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/tomography11040047","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Use of Open-Source Large Language Models for Automatic Synthesis of the Entire Imaging Medical Records of Patients: A Feasibility Study.
Background/objectives: Reviewing the entire history of imaging exams of a single patient's records is an essential step in clinical practice, but it is time and resource consuming, with potential negative effects on workflow and on the quality of medical decisions. The main objective of this study was to evaluate the applicability of three open-source large language models (LLMs) for the automatic generation of concise summaries of patient's imaging records. Secondary objectives were to assess correlations among the LLMs and to evaluate the length reduction provided by each model.
Methods: Three state-of-the-art open-source large language models were selected: Llama 3.2 11B, Mistral 7B, and Falcon 7B. Each model was given a set of radiology reports. The summaries produced by the models were evaluated by two experienced radiologists and one experienced clinical physician using standardized metrics.
Results: A variable number of radiological reports (n = 12-56) from four patients were selected and evaluated. The summaries generated by the three LLM showed a good level of accuracy compared with the information contained in the original reports, with positive ratings on both clinical relevance and ease of reference. According to the experts' evaluations, the use of the summaries generated by LLMs could help to reduce the time spent on reviewing the previous imaging examinations performed, preserving the quality of clinical data.
Conclusions: Our results suggest that LLMs are able to generate summaries of the imaging history of patients, and these summaries could improve radiology workflow making it easier to manage large volumes of reports.
TomographyMedicine-Radiology, Nuclear Medicine and Imaging
CiteScore
2.70
自引率
10.50%
发文量
222
期刊介绍:
TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine.
Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians.
Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.