深度学习驱动的肩部MRI简化方案:临床实践中的诊断准确性。

IF 2.2 4区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Giovanni Foti, Flavio Spoto, Thomas Mignolli, Alessandro Spezia, Luigi Romano, Guglielmo Manenti, Nicolò Cardobi, Paolo Avanzi
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引用次数: 0

摘要

背景:深度学习(DL)重建技术在保持图像质量的同时减少了MRI采集时间。然而,不同加速度因素对肩关节MRI诊断准确性的影响在临床实践中尚未得到探讨。目的:本研究的目的是评估与临床实践中的标准方案相比,2倍和4倍dl加速肩部MRI方案的诊断准确性。材料和方法:在这项前瞻性单中心研究中,88例连续患者(男性49例,女性39例;平均年龄,51岁)在2023年6月至2024年1月期间接受了标准、2倍(DL2)和4倍(DL4)加速方案的肩部MRI检查。4位独立的放射科医生(经验范围:4-25年)评估了骨髓水肿(BME)、肩袖撕裂和唇部病变的存在。计算灵敏度、特异性和观察者间一致性。诊断信心采用4分制进行评估。通过将放射科医生分为≤10年和≤10年的经验来分析读者经验的影响。结果:两种加速方案均表现出较高的诊断准确性。对于BME检测,DL2和DL4的灵敏度和特异性均达到100%。在肩袖评估中,DL2的敏感性为98-100%,特异性为99-100%,而DL4的敏感性为95-98%,特异性为99-100%。唇裂检测DL2灵敏度为100%,DL4灵敏度略低(89-100%)。观察者之间的一致性非常好(Kendall的W = 0.92-0.98)。读者体验对诊断性能没有显著影响。DL2和DL4的ROC曲线下面积分别为0.94和0.90 (p = 0.32)。临床意义:实施dl加速协议,特别是DL2,可以在保持诊断可靠性的同时减少50%的采集时间,从而提高工作流程效率。这可以在不影响诊断质量的情况下增加患者的吞吐量和获得MRI检查的机会。结论:dl加速肩部MRI方案具有较高的诊断准确性,DL2显示的性能几乎与标准方案相同。虽然DL4保持了可接受的诊断准确性,但它对细微病变的敏感性略有降低,特别是在经验不足的读者中。DL2协议代表了采集时间减少和诊断信心之间的最佳平衡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Deep Learning-Driven Abbreviated Shoulder MRI Protocols: Diagnostic Accuracy in Clinical Practice.

Background: Deep learning (DL) reconstruction techniques have shown promise in reducing MRI acquisition times while maintaining image quality. However, the impact of different acceleration factors on diagnostic accuracy in shoulder MRI remains unexplored in clinical practice.

Purpose: The purpose of this study was to evaluate the diagnostic accuracy of 2-fold and 4-fold DL-accelerated shoulder MRI protocols compared to standard protocols in clinical practice.

Materials and methods: In this prospective single-center study, 88 consecutive patients (49 males, 39 females; mean age, 51 years) underwent shoulder MRI examinations using standard, 2-fold (DL2), and 4-fold (DL4) accelerated protocols between June 2023 and January 2024. Four independent radiologists (experience range: 4-25 years) evaluated the presence of bone marrow edema (BME), rotator cuff tears, and labral lesions. The sensitivity, specificity, and interobserver agreement were calculated. Diagnostic confidence was assessed using a 4-point scale. The impact of reader experience was analyzed by stratifying the radiologists into ≤10 and >10 years of experience.

Results: Both accelerated protocols demonstrated high diagnostic accuracy. For BME detection, DL2 and DL4 achieved 100% sensitivity and specificity. In rotator cuff evaluation, DL2 showed a sensitivity of 98-100% and specificity of 99-100%, while DL4 maintained a sensitivity of 95-98% and specificity of 99-100%. Labral tear detection showed perfect sensitivity (100%) with DL2 and slightly lower sensitivity (89-100%) with DL4. Interobserver agreement was excellent across the protocols (Kendall's W = 0.92-0.98). Reader experience did not significantly impact diagnostic performance. The area under the ROC curve was 0.94 for DL2 and 0.90 for DL4 (p = 0.32).

Clinical implications: The implementation of DL-accelerated protocols, particularly DL2, could improve workflow efficiency by reducing acquisition times by 50% while maintaining diagnostic reliability. This could increase patient throughput and accessibility to MRI examinations without compromising diagnostic quality.

Conclusions: DL-accelerated shoulder MRI protocols demonstrate high diagnostic accuracy, with DL2 showing performance nearly identical to that of the standard protocol. While DL4 maintains acceptable diagnostic accuracy, it shows a slight sensitivity reduction for subtle pathologies, particularly among less experienced readers. The DL2 protocol represents an optimal balance between acquisition time reduction and diagnostic confidence.

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来源期刊
Tomography
Tomography Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
2.70
自引率
10.50%
发文量
222
期刊介绍: TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine. Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians. Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.
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