Clinical Decision Support Leveraging Health Information Exchange improves Concordance with Patient's Resuscitation Orders and End-Of-Life Wishes.

Objectives Improve concordance between patient end-of-life preferences and code status orders by incorporating data from a state registry with Clinical Decision Support (CDS) within the electronic health record (EHR) to preserve patient autonomy and ensure that patients receive care that aligns with their wishes. Methods Leveraging a Health Information exchange (HIE) interface between the New York State Medical Orders for Life-Sustaining Treatment (eMOLST) registry and the EHR of our academic health system, we developed a bundled CDS intervention that displays eMOLST information at the time of code status ordering and provides an in-line alert when providers enter a resuscitation order discordant with wishes documented in the eMOLST registry. To evaluate this intervention, we performed a segmented regression analysis of an interrupted times series to compare percentage of discordant orders before and after implementation among all hospitalizations for which an eMOLST was available. Results We identified a total of 3648 visits that had an eMOLST filed prior to inpatient admission and a code status order placed during admission. There was a statistically significant decrease of discordant resuscitation orders of -5.95% after the intervention went live, with a relative risk reduction of 25%, [95% CI: -9.95%, -1.94%, p=0.009] in the pre- and post-intervention period. Logistic regression model after adjusting for co-variates showed an average marginal effect of -5.12% after the intervention [CI =-9.75%, -0.50%, p=0.03]. Conclusions Our intervention resulted in a decrease in discordant resuscitation orders. This study demonstrates that accessibility to eMOLST data within the provider workflow supported by CDS can reduce discrepancies between patient end-of-life wishes and hospital code status orders.