上颌骨后区软骨肉瘤。

IF 3.2 Q2 PATHOLOGY
Jonathan França da Silva Cavalcanti, Márcia Maria da Fonseca Silveira, Weslay Rodrigues da Silva, Rebeka Thiara Nascimento Dos Santos, Igor Batista Camargo, Ana Paula Veras Sobral
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引用次数: 0

摘要

背景:软骨肉瘤是一种以产生软骨基质为特征的恶性肿瘤。病例报告:我们报告一例58岁男性患者,因右上颌骨后区肿胀,持续8个月,既往有该区域纤维骨性病变史,转诊至颌面外科和创伤科。口腔内检查发现17号和18号牙区有圆形病变伴溃疡,触诊后牢固。全景x线片示右上颌骨一絮凝型不透光病变,计算机断层扫描示高密度病变含低密度区。组织病理学分析显示存在未成熟软骨,圆形肿瘤细胞,大小不一的细胞核,强烈的多形性,导致软骨肉瘤诊断。患者接受了手术切除和放疗,经过一年的随访,没有出现复发的迹象。结论:尽管软骨肉瘤在颌骨中罕见,但在该区域骨肿大的鉴别诊断中应考虑软骨肉瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chondrosarcoma in the Posterior Maxilla Region.

Background: Chondrosarcoma is a malignant neoplasm characterized by the production of a cartilaginous matrix.

Case report: We present the case of a 58-year-old male patient referred to the maxillofacial surgery and traumatology service due to swelling in the posterior region of the right maxilla, with a duration of 8 months, and a previous history of a fibro-osseous lesion in the region. Intraoral examination revealed a rounded lesion with ulceration, firm upon palpation, in the area of teeth 17 and 18. The panoramic radiograph revealed a radiopaque lesion with a flocculated pattern in the right maxilla, and computed tomography showed a hyperdense lesion containing hypodense areas. Histopathological analysis revealed the presence of immature cartilage, with rounded neoplastic cells, nuclei of varied sizes, and intense pleomorphism, leading to a diagnosis of chondrosarcoma. The patient underwent surgical resection followed by radiotherapy and, after one year of follow-up, has shown no signs of recurrence.

Conclusions: Although rare in gnathic bones, chondrosarcoma should be considered in the differential diagnosis of osseous enlargement in this region.

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来源期刊
CiteScore
5.70
自引率
9.50%
发文量
99
期刊介绍: Head & Neck Pathology presents scholarly papers, reviews and symposia that cover the spectrum of human surgical pathology within the anatomic zones of the oral cavity, sinonasal tract, larynx, hypopharynx, salivary gland, ear and temporal bone, and neck. The journal publishes rapid developments in new diagnostic criteria, intraoperative consultation, immunohistochemical studies, molecular techniques, genetic analyses, diagnostic aids, experimental pathology, cytology, radiographic imaging, and application of uniform terminology to allow practitioners to continue to maintain and expand their knowledge in the subspecialty of head and neck pathology. Coverage of practical application to daily clinical practice is supported with proceedings and symposia from international societies and academies devoted to this field. Single-blind peer review The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.
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