{"title":"代谢危险因素与长COVID：新西兰奥特罗阿的横断面研究","authors":"Bailey Yee, Fiona McKenzie, Lis Ellison-Loschmann, Lynne Russell, Mona Jeffreys","doi":"10.26635/6965.6699","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>To describe the association between metabolic risk factors and the risk of developing long COVID in Aotearoa New Zealand.</p><p><strong>Methods: </strong>Individuals aged 16 years and above who had confirmed or probable COVID-19 before December 2021 were eligible for inclusion. Metabolic risk factors were high body mass index (BMI, ≥25kg/m2), high blood pressure, diabetes, heart disease and stroke. Logistic regression was used to estimate the association between metabolic risk factors and long COVID.</p><p><strong>Results: </strong>Of the 990 survey respondents, 21.9% met the definition of long COVID. After adjusting for socio-demographic factors, COVID-19 vaccination and hospitalisation, high BMI was strongly associated with long COVID (adjusted odds ratio [aOR] 2.35; 95% confidence interval [CI] 1.33-4.17, p=0.003). There was a suggestion of an association between heart disease and long COVID (aOR 4.31; 95% CI 0.80-23.3, p=0.090). No other metabolic factors were associated with long COVID. Among Māori, no associations were found between high BMI and long COVID compared with underweight/normal BMI.</p><p><strong>Conclusion: </strong>High BMI as a risk factor adds to accumulating evidence on the aetiology of long COVID.</p>","PeriodicalId":48086,"journal":{"name":"NEW ZEALAND MEDICAL JOURNAL","volume":"138 1613","pages":"12-23"},"PeriodicalIF":1.2000,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metabolic risk factors and long COVID: a cross-sectional study in Aotearoa New Zealand.\",\"authors\":\"Bailey Yee, Fiona McKenzie, Lis Ellison-Loschmann, Lynne Russell, Mona Jeffreys\",\"doi\":\"10.26635/6965.6699\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>To describe the association between metabolic risk factors and the risk of developing long COVID in Aotearoa New Zealand.</p><p><strong>Methods: </strong>Individuals aged 16 years and above who had confirmed or probable COVID-19 before December 2021 were eligible for inclusion. Metabolic risk factors were high body mass index (BMI, ≥25kg/m2), high blood pressure, diabetes, heart disease and stroke. Logistic regression was used to estimate the association between metabolic risk factors and long COVID.</p><p><strong>Results: </strong>Of the 990 survey respondents, 21.9% met the definition of long COVID. After adjusting for socio-demographic factors, COVID-19 vaccination and hospitalisation, high BMI was strongly associated with long COVID (adjusted odds ratio [aOR] 2.35; 95% confidence interval [CI] 1.33-4.17, p=0.003). There was a suggestion of an association between heart disease and long COVID (aOR 4.31; 95% CI 0.80-23.3, p=0.090). No other metabolic factors were associated with long COVID. Among Māori, no associations were found between high BMI and long COVID compared with underweight/normal BMI.</p><p><strong>Conclusion: </strong>High BMI as a risk factor adds to accumulating evidence on the aetiology of long COVID.</p>\",\"PeriodicalId\":48086,\"journal\":{\"name\":\"NEW ZEALAND MEDICAL JOURNAL\",\"volume\":\"138 1613\",\"pages\":\"12-23\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2025-04-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"NEW ZEALAND MEDICAL JOURNAL\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26635/6965.6699\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"NEW ZEALAND MEDICAL JOURNAL","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26635/6965.6699","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
目的：了解新西兰奥特罗阿地区代谢危险因素与新冠肺炎发病风险的关系。方法：在2021年12月之前确诊或可能感染COVID-19的16岁及以上的个体符合纳入条件。代谢危险因素为高体重指数（BMI,≥25kg/m2）、高血压、糖尿病、心脏病和脑卒中。采用Logistic回归估计代谢危险因素与长COVID之间的相关性。结果：990名调查对象中，21.9%符合长冠定义。在调整了社会人口因素、COVID-19疫苗接种和住院治疗后，高BMI与长COVID-19密切相关(调整后优势比[aOR] 2.35；95%置信区间[CI] 1.33-4.17, p=0.003)。心脏病与长COVID之间存在关联(aOR 4.31；95% CI 0.80-23.3, p=0.090)。其他代谢因素与长冠无相关性。在Māori中，与体重不足/正常BMI相比，高BMI与长COVID之间没有关联。结论：高BMI作为一个危险因素增加了长期COVID病因学证据的积累。
Metabolic risk factors and long COVID: a cross-sectional study in Aotearoa New Zealand.
Aim: To describe the association between metabolic risk factors and the risk of developing long COVID in Aotearoa New Zealand.
Methods: Individuals aged 16 years and above who had confirmed or probable COVID-19 before December 2021 were eligible for inclusion. Metabolic risk factors were high body mass index (BMI, ≥25kg/m2), high blood pressure, diabetes, heart disease and stroke. Logistic regression was used to estimate the association between metabolic risk factors and long COVID.
Results: Of the 990 survey respondents, 21.9% met the definition of long COVID. After adjusting for socio-demographic factors, COVID-19 vaccination and hospitalisation, high BMI was strongly associated with long COVID (adjusted odds ratio [aOR] 2.35; 95% confidence interval [CI] 1.33-4.17, p=0.003). There was a suggestion of an association between heart disease and long COVID (aOR 4.31; 95% CI 0.80-23.3, p=0.090). No other metabolic factors were associated with long COVID. Among Māori, no associations were found between high BMI and long COVID compared with underweight/normal BMI.
Conclusion: High BMI as a risk factor adds to accumulating evidence on the aetiology of long COVID.
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