Ali Afrasiabi, Johannes L du Pisanie, Bahareh Gholami, Hui Wang, Sandra Gad, Nima Kokabi
{"title":"90后PET剂量测定。","authors":"Ali Afrasiabi, Johannes L du Pisanie, Bahareh Gholami, Hui Wang, Sandra Gad, Nima Kokabi","doi":"10.1016/j.cpet.2025.03.002","DOIUrl":null,"url":null,"abstract":"<p><p>Transarterial radioembolization with yttrium-90 is widely used to treat unresectable liver cancer by delivering radiation directly to tumors. While post-treatment imaging generally relies on single-photon emission computed tomography (SPECT) and SPECT/computed tomography (CT), lower signal-to-noise ratio and spatial resolution limit its application. PET/CT and PET/MR imaging have proven to provide more effective image quality, yielding clearer images for accurate dose quantification and correlation with treatment response. PET-based imaging is crucial for refining dose-response and dose-toxicity relationships in personalized dosimetry, although its limited availability challenges its widespread use.</p>","PeriodicalId":94168,"journal":{"name":"PET clinics","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Post-Y90 PET Dosimetry.\",\"authors\":\"Ali Afrasiabi, Johannes L du Pisanie, Bahareh Gholami, Hui Wang, Sandra Gad, Nima Kokabi\",\"doi\":\"10.1016/j.cpet.2025.03.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Transarterial radioembolization with yttrium-90 is widely used to treat unresectable liver cancer by delivering radiation directly to tumors. While post-treatment imaging generally relies on single-photon emission computed tomography (SPECT) and SPECT/computed tomography (CT), lower signal-to-noise ratio and spatial resolution limit its application. PET/CT and PET/MR imaging have proven to provide more effective image quality, yielding clearer images for accurate dose quantification and correlation with treatment response. PET-based imaging is crucial for refining dose-response and dose-toxicity relationships in personalized dosimetry, although its limited availability challenges its widespread use.</p>\",\"PeriodicalId\":94168,\"journal\":{\"name\":\"PET clinics\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"PET clinics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.cpet.2025.03.002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"PET clinics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.cpet.2025.03.002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Transarterial radioembolization with yttrium-90 is widely used to treat unresectable liver cancer by delivering radiation directly to tumors. While post-treatment imaging generally relies on single-photon emission computed tomography (SPECT) and SPECT/computed tomography (CT), lower signal-to-noise ratio and spatial resolution limit its application. PET/CT and PET/MR imaging have proven to provide more effective image quality, yielding clearer images for accurate dose quantification and correlation with treatment response. PET-based imaging is crucial for refining dose-response and dose-toxicity relationships in personalized dosimetry, although its limited availability challenges its widespread use.
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