【炎性肠病患者肌肉减少症的肌肉超声诊断】。

IF 0.3 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Terapevticheskii Arkhiv Pub Date : 2025-03-26 DOI:10.26442/00403660.2025.02.203204

O E Akchurina, D D Mukhametova, A K Odintsova, D I Abdulganieva

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引用次数: 0

摘要

目的：应用超声评估炎症性肠病（IBD）患者的肌肉质量。材料与方法：选取喀山共和国临床医院消化科102例IBD住院患者为研究对象。其中，溃疡性结肠炎患者占49%，克罗恩病患者占51%，对照组（CG） 10人。IBD组的中位年龄为39.5岁[28.5；50年，在CG - 37 [26；38年。IBD组52例（51%），CG组5例（50%）。检查患者的身体质量指数（BMI）、优势侧上臂中围（MUAC, cm）和大腿中围（MTC, cm）；使用ABC-02“MEDASS”装置进行人体成分生物阻抗分析；超声检查前侧两点的肌肉厚度：肩中部超声厚度（US-MUAC），大腿中部超声厚度（US-MTC），使用腕部测力仪测力，评估营养状况。结果：按BMI分布：正常57例（55.9%）；缺乏——12人（11.8%）；超重——25人（24.5%）；肥胖——8人（7.8%）。IBD女性的MUAC中位数为28 [24.9；31] cm，在CG - 28 [27；28.5] cm (p < 0.05)；男性IBD患者29.8 [27]；32] cm，在CG - 33 [31；34] cm (pppp>0.05)；男性IBD患者26.45例[22.87]；29.24]毫米，在CG 21.54 [21.18；25.13] mm （p < 0.05）。女性IBD的US-MTC中位数为31.05 [23.21；37.11] mm, CG 41.30 [35.55]；41.74] mm (ppr=0.557；公关= 0.448;公关= 0.666;公关= 0.505;公关= 0.376;公关= 0.373;结论：IBD患者MTC低于CG患者。女性和男性IBD患者的US-MTC低于CG患者，这与MTC、BMI、生物阻抗测量的骨骼肌质量和动力学测量的握力相关。

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[Ultrasound of muscles for the diagnosis of sarcopenia in patients with inflammatory bowel diseases].

Aim: To assess the muscle mass of patients with inflammatory bowel disease (IBD) using ultrasound.

Materials and methods: 102 IBD patients hospitalized in gastroenterology department of Republican Clinical Hospital (Kazan) were involved in the study. Among them, 49% of patients with ulcerative colitis, 51% with Crohn's disease, 10 people made up the control group (CG). The median age in the IBD group was 39.5 [28.5; 50] years, in the CG - 37 [26; 38] years. There were 52 (51%) women in the IBD group and 5 (50%) in the CG group. Patients were examined to assess body mass index (BMI), mid-upper arm circumference (MUAC, cm) and mid-thigh circumference (MTC, cm) of the dominant side; bioimpedance analysis of body composition using the ABC-02 "MEDASS" device; ultrasound examination of muscle thickness at two points on the leading side: ultrasound thickness of the middle of the shoulder (US-MUAC), ultrasound thickness of the middle of the thigh (US-MTC), dynamometry using a wrist dynamometer, assessment of nutritional status.

Results: According to BMI, patients were distributed as follows: normal in 57 (55.9%) patients; deficiency - in 12 (11.8%); overweight - 25 (24.5%); obesity - 8 (7.8%). Median MUAC in women with IBD was 28 [24.9; 31] cm, in CG - 28 [27; 28.5] cm (p>0.05); in men with IBD 29.8 [27; 32] cm, in CG - 33 [31; 34] cm (p<0.05). The median MTC in women with IBD was 54.25 [48.15; 58.10] cm, in CG - 61.5 [56; 67] cm (p<0.05); in men with IBD 48 [46; 51.4] cm, in GC - 54 [53; 54] cm (p<0.05). The median US-MUAC in women with IBD was 19.60 [18.23; 22.84] mm, CG 22.49 [20.41; 22.66] (p>0.05); in men with IBD 26.45 [22.87; 29.24] mm, in CG 21.54 [21.18; 25.13] mm (p>0.05). Median US-MTC in women with IBD was 31.05 [23.21; 37.11] mm, CG 41.30 [35.55; 41.74] mm (p<0.05), in men with IBD 30.90 [25.64; 39.99] mm, in CG 40.67 [39.10; 41.84] (p<0.05). According to the results of bioimpedansometry, the skeletal muscle mass index (SMI) was low in 32% of patients, normal in 65%, and above normal in 3%. US-MUAC correlated with MUAC (r=0.557; p<0.05), with BMI (r=0.448; p<0.05), with SMI (r=0.666; p<0.05). US-MTC correlated with MTC (r=0.505; p<0.05), with BMI (r=0.376; p<0.05), with SMI (r=0.373; p<0.05).

Conclusion: In patients with IBD, MTC was lower than in CG. US-MTC in women and men with IBD was lower than in CG, which correlated with MTC, BMI, skeletal muscle mass according to bioimpedance measurements and grip strength according to dynamometry.

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来源期刊

Terapevticheskii Arkhiv 医学-医学：内科

CiteScore

1.40

自引率

33.30%

发文量

171

审稿时长

3-8 weeks

期刊介绍： Терапевтический архив The journal was founded by the prominent Russian therapists M.P. Konchalovsky and G.F. Lang in 1923. Then its editors-in-chief were Professors V.N. Vinogradov and A.G. Gukasyan. Since 1972, E.I. Chazov, Academician of the Russian Academy of Sciences, has been heading the editorial board of the journal. Over 90 years, there have been more than 1000 issues where the authors and editorial staff have done their best for readers to keep abreast of current advances in medical science and practice and for physicians to master the advanced principles of recognition and treatment of a wide spectrum of visceral diseases. The papers published in the journal (editorials, original articles, lectures, reviews, etc.) cover both current scientific achievements and practical experience in diagnosing, treating, and preventing visceral diseases. The authors of publications are not only Russian, but also foreign scientists and physicians. All papers are peer-reviewed by highly qualified Russian specialists. The journal is published monthly. Traditionally, each issue has predominantly certain thematic areas covering individual therapy specializations. Every year, one of the issues is devoted to related problems in practical medicine (allergology and immunology, neurology and psychiatry, obstetrics, oncology, etc.). This all draws the attention of the reading public to the journal. The journal is indexed in RSCI (Russian Science Citation Index), PubMed/Medline, Index Medicus, Scopus/EMBASE, Web of Science Core Collection (Science Citation Index Expanded), Web of Science (Russian Science Citation Index - RSCI, Current Contents Connect, BIOSIS Previews), Google Scholar, Ulrich''s Periodicals Directory. The journal is included in the list of periodicals recommended by the Higher Attestation Committee for publishing the papers containing the basic materials of doctoral and candidate dissertations. By the decision of the Presidium of the Russian Academy of Medical Sciences, the “Therapevticheskiy Arkhiv” was awarded the Botkin medal. It was admitted to the European Association of Sciences Editors (EASE). The journal was honored with the Golden Press Fund decoration at the 13th International Press Professional Exhibition.