Ignacio Cancela-Cilleruelo, Jorge Rodríguez-Jiménez, José L Arias-Buría, Marcos J Navarro-Santana, Lars Arendt-Nielsen, César Fernández-de-Las-Peñas
{"title":"疼痛性肌腱病/过度使用性损伤患者神经病变样症状的存在：系统回顾和荟萃分析","authors":"Ignacio Cancela-Cilleruelo, Jorge Rodríguez-Jiménez, José L Arias-Buría, Marcos J Navarro-Santana, Lars Arendt-Nielsen, César Fernández-de-Las-Peñas","doi":"10.1097/AJP.0000000000001292","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This meta-analysis evaluated the prevalence of neuropathic-like symptoms in individuals with painful tendinopathies/overuse injuries.</p><p><strong>Methods: </strong>Electronic literature searches on MEDLINE, CINAHL, PubMed, SCOPUS and Web of Science databases were conducted up to January 20th, 2025. Studies reporting the prevalence of neuropathic-like symptoms in painful tendinopathy/overuse injury were included. The methodological quality was assessed with Newcastle-Ottawa Quality Assessment Scale in cohort/case-control studies or Physiotherapy Evidence Database (PEDro) in clinical trials. Random-effects models were used for meta-analytical pooled prevalence of neuropathic-like symptoms.</p><p><strong>Results: </strong>From 1,285 studies identified, eight (one case-control, five cohorts and two clinical trials) met inclusion criteria. The sample included 920 subjects with painful tendinopathy/overuse injury (47.6% female, age: 51, SD: 12.5 years). All studies included self-reported questionnaires for evaluating neuropathic-like symptomatology. The methodological quality was moderate-high. The overall prevalence of neuropathic-like symptoms in painful tendinopathies was 30% (95%CI 22%-38%, n=8, I2=79%). The prevalence by each tendinopathy was: plantar heel pain (44%, 95%CI 17%-75%, n=2, I2=96%), lateral epicondylalgia (42%, 95%CI 30%-56%, n=2, I2=30%), insertional Achilles tendinopathy (38%, 95%CI 20%-60%, n=2, I2= 71%), greater trochanteric pain syndrome (32%, 95%CI 26%-39%, n=2, I2=0%), patellar-quadricipital tendinopathy (16%, 95%CI 5%-41%, n=3, I2=29%), non-insertional Achilles tendinopathy (11%, 95%CI 2%-41%, n=5, I2=86%).</p><p><strong>Conclusion: </strong>This meta-analysis suggests the presence of neuropathic-like symptoms in 30% of subjects with painful tendinopathy, although this prevalence rate depends on specific condition. Identification of neuropathic symptoms in musculoskeletal pain conditions is important for diagnosis as it impacts its management.</p>","PeriodicalId":50678,"journal":{"name":"Clinical Journal of Pain","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Presence of Neuropathic-Like Symptoms in Individuals with Painful Tendinopathy/Overuse Injuries: A Systematic Review and Meta-Analysis.\",\"authors\":\"Ignacio Cancela-Cilleruelo, Jorge Rodríguez-Jiménez, José L Arias-Buría, Marcos J Navarro-Santana, Lars Arendt-Nielsen, César Fernández-de-Las-Peñas\",\"doi\":\"10.1097/AJP.0000000000001292\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This meta-analysis evaluated the prevalence of neuropathic-like symptoms in individuals with painful tendinopathies/overuse injuries.</p><p><strong>Methods: </strong>Electronic literature searches on MEDLINE, CINAHL, PubMed, SCOPUS and Web of Science databases were conducted up to January 20th, 2025. Studies reporting the prevalence of neuropathic-like symptoms in painful tendinopathy/overuse injury were included. The methodological quality was assessed with Newcastle-Ottawa Quality Assessment Scale in cohort/case-control studies or Physiotherapy Evidence Database (PEDro) in clinical trials. Random-effects models were used for meta-analytical pooled prevalence of neuropathic-like symptoms.</p><p><strong>Results: </strong>From 1,285 studies identified, eight (one case-control, five cohorts and two clinical trials) met inclusion criteria. The sample included 920 subjects with painful tendinopathy/overuse injury (47.6% female, age: 51, SD: 12.5 years). All studies included self-reported questionnaires for evaluating neuropathic-like symptomatology. The methodological quality was moderate-high. The overall prevalence of neuropathic-like symptoms in painful tendinopathies was 30% (95%CI 22%-38%, n=8, I2=79%). The prevalence by each tendinopathy was: plantar heel pain (44%, 95%CI 17%-75%, n=2, I2=96%), lateral epicondylalgia (42%, 95%CI 30%-56%, n=2, I2=30%), insertional Achilles tendinopathy (38%, 95%CI 20%-60%, n=2, I2= 71%), greater trochanteric pain syndrome (32%, 95%CI 26%-39%, n=2, I2=0%), patellar-quadricipital tendinopathy (16%, 95%CI 5%-41%, n=3, I2=29%), non-insertional Achilles tendinopathy (11%, 95%CI 2%-41%, n=5, I2=86%).</p><p><strong>Conclusion: </strong>This meta-analysis suggests the presence of neuropathic-like symptoms in 30% of subjects with painful tendinopathy, although this prevalence rate depends on specific condition. 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Presence of Neuropathic-Like Symptoms in Individuals with Painful Tendinopathy/Overuse Injuries: A Systematic Review and Meta-Analysis.
Objective: This meta-analysis evaluated the prevalence of neuropathic-like symptoms in individuals with painful tendinopathies/overuse injuries.
Methods: Electronic literature searches on MEDLINE, CINAHL, PubMed, SCOPUS and Web of Science databases were conducted up to January 20th, 2025. Studies reporting the prevalence of neuropathic-like symptoms in painful tendinopathy/overuse injury were included. The methodological quality was assessed with Newcastle-Ottawa Quality Assessment Scale in cohort/case-control studies or Physiotherapy Evidence Database (PEDro) in clinical trials. Random-effects models were used for meta-analytical pooled prevalence of neuropathic-like symptoms.
Results: From 1,285 studies identified, eight (one case-control, five cohorts and two clinical trials) met inclusion criteria. The sample included 920 subjects with painful tendinopathy/overuse injury (47.6% female, age: 51, SD: 12.5 years). All studies included self-reported questionnaires for evaluating neuropathic-like symptomatology. The methodological quality was moderate-high. The overall prevalence of neuropathic-like symptoms in painful tendinopathies was 30% (95%CI 22%-38%, n=8, I2=79%). The prevalence by each tendinopathy was: plantar heel pain (44%, 95%CI 17%-75%, n=2, I2=96%), lateral epicondylalgia (42%, 95%CI 30%-56%, n=2, I2=30%), insertional Achilles tendinopathy (38%, 95%CI 20%-60%, n=2, I2= 71%), greater trochanteric pain syndrome (32%, 95%CI 26%-39%, n=2, I2=0%), patellar-quadricipital tendinopathy (16%, 95%CI 5%-41%, n=3, I2=29%), non-insertional Achilles tendinopathy (11%, 95%CI 2%-41%, n=5, I2=86%).
Conclusion: This meta-analysis suggests the presence of neuropathic-like symptoms in 30% of subjects with painful tendinopathy, although this prevalence rate depends on specific condition. Identification of neuropathic symptoms in musculoskeletal pain conditions is important for diagnosis as it impacts its management.
期刊介绍：
The Clinical Journal of Pain explores all aspects of pain and its effective treatment, bringing readers the insights of leading anesthesiologists, surgeons, internists, neurologists, orthopedists, psychiatrists and psychologists, clinical pharmacologists, and rehabilitation medicine specialists. This peer-reviewed journal presents timely and thought-provoking articles on clinical dilemmas in pain management; valuable diagnostic procedures; promising new pharmacological, surgical, and other therapeutic modalities; psychosocial dimensions of pain; and ethical issues of concern to all medical professionals. The journal also publishes Special Topic issues on subjects of particular relevance to the practice of pain medicine.
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