Teyyeb Azeem Janjua, Anam Hassan, Waqar Muzaffar, Shagufta Parveen, Muhammad Shahid, Jawwad Ahmad
{"title":"网膜内皮角膜移植术与穿透性角膜移植术视力效果的比较。","authors":"Teyyeb Azeem Janjua, Anam Hassan, Waqar Muzaffar, Shagufta Parveen, Muhammad Shahid, Jawwad Ahmad","doi":"10.29271/jcpsp.2025.04.463","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To compare the visual outcome in patients undergoing penetrating keratoplasty (PKP) with descemet membrane endothelial keratoplasty (DMEK).</p><p><strong>Study design: </strong>A quasi-experimental study. Place and Duration of the Study: Department of Eye, The Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan, from January 2022 to June 2023.</p><p><strong>Methodology: </strong>A prospective analysis of fourteen patients who underwent PKP in comparison with another group of fourteen patients who got the DMEK surgery was done. The evaluation of visual and refractive outcomes was done postoperatively. Fisher's exact test was used to compare visual acuity grouped into categories between two surgical procedures.</p><p><strong>Results: </strong>Fourteen eyes from each group that were PKP and DMEK were included in the analysis. The best corrected visual acuity after 6 months was better in the DMEK group compared with the PKP group (p = 0.003) and these results were consistent after twelve months (p = 0.006) keeping the DMEK group superior in visual outcome over the PKP group.</p><p><strong>Conclusion: </strong>PKP and DMEK play distinct roles in the treatment of corneal disorders, each with its own set of indications. However, DMEK resulted in a better visual outcome when compared to the PKP. Although quality of life improved in both groups, it was found to be better in the DMEK group compared to the PKP group.</p><p><strong>Key words: </strong>Visual acuity, Descemet membrane endothelial keratoplasty, Penetrating keratoplasty, Corneal transplant.</p>","PeriodicalId":54905,"journal":{"name":"Jcpsp-Journal of the College of Physicians and Surgeons Pakistan","volume":"35 4","pages":"463-467"},"PeriodicalIF":0.7000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of Visual Outcome of Successful Descemet Membrane Endothelial Keratoplasty and Penetrating Keratoplasty.\",\"authors\":\"Teyyeb Azeem Janjua, Anam Hassan, Waqar Muzaffar, Shagufta Parveen, Muhammad Shahid, Jawwad Ahmad\",\"doi\":\"10.29271/jcpsp.2025.04.463\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To compare the visual outcome in patients undergoing penetrating keratoplasty (PKP) with descemet membrane endothelial keratoplasty (DMEK).</p><p><strong>Study design: </strong>A quasi-experimental study. Place and Duration of the Study: Department of Eye, The Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan, from January 2022 to June 2023.</p><p><strong>Methodology: </strong>A prospective analysis of fourteen patients who underwent PKP in comparison with another group of fourteen patients who got the DMEK surgery was done. The evaluation of visual and refractive outcomes was done postoperatively. Fisher's exact test was used to compare visual acuity grouped into categories between two surgical procedures.</p><p><strong>Results: </strong>Fourteen eyes from each group that were PKP and DMEK were included in the analysis. The best corrected visual acuity after 6 months was better in the DMEK group compared with the PKP group (p = 0.003) and these results were consistent after twelve months (p = 0.006) keeping the DMEK group superior in visual outcome over the PKP group.</p><p><strong>Conclusion: </strong>PKP and DMEK play distinct roles in the treatment of corneal disorders, each with its own set of indications. However, DMEK resulted in a better visual outcome when compared to the PKP. Although quality of life improved in both groups, it was found to be better in the DMEK group compared to the PKP group.</p><p><strong>Key words: </strong>Visual acuity, Descemet membrane endothelial keratoplasty, Penetrating keratoplasty, Corneal transplant.</p>\",\"PeriodicalId\":54905,\"journal\":{\"name\":\"Jcpsp-Journal of the College of Physicians and Surgeons Pakistan\",\"volume\":\"35 4\",\"pages\":\"463-467\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jcpsp-Journal of the College of Physicians and Surgeons Pakistan\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.29271/jcpsp.2025.04.463\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jcpsp-Journal of the College of Physicians and Surgeons Pakistan","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.29271/jcpsp.2025.04.463","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Comparison of Visual Outcome of Successful Descemet Membrane Endothelial Keratoplasty and Penetrating Keratoplasty.
Objective: To compare the visual outcome in patients undergoing penetrating keratoplasty (PKP) with descemet membrane endothelial keratoplasty (DMEK).
Study design: A quasi-experimental study. Place and Duration of the Study: Department of Eye, The Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan, from January 2022 to June 2023.
Methodology: A prospective analysis of fourteen patients who underwent PKP in comparison with another group of fourteen patients who got the DMEK surgery was done. The evaluation of visual and refractive outcomes was done postoperatively. Fisher's exact test was used to compare visual acuity grouped into categories between two surgical procedures.
Results: Fourteen eyes from each group that were PKP and DMEK were included in the analysis. The best corrected visual acuity after 6 months was better in the DMEK group compared with the PKP group (p = 0.003) and these results were consistent after twelve months (p = 0.006) keeping the DMEK group superior in visual outcome over the PKP group.
Conclusion: PKP and DMEK play distinct roles in the treatment of corneal disorders, each with its own set of indications. However, DMEK resulted in a better visual outcome when compared to the PKP. Although quality of life improved in both groups, it was found to be better in the DMEK group compared to the PKP group.
期刊介绍：
Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991.
Established with the primary aim of promotion and dissemination of medical research and contributed by scholars of biomedical sciences from Pakistan and abroad, it carries original research papers, , case reports, review articles, articles on medical education, commentaries, short communication, new technology, editorials and letters to the editor. It covers the core biomedical health science subjects, basic medical sciences and emerging community problems, prepared in accordance with the “Uniform requirements for submission to bio-medical journals” laid down by International Committee of Medical Journals Editors (ICMJE). All publications of JCPSP are peer reviewed by subject specialists from Pakistan and locally and abroad.
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