成人幕部模拟脑膜瘤成神经管细胞瘤1例报告及系统回顾。

Surgical neurology international Pub Date : 2025-04-18 eCollection Date: 2025-01-01 DOI:10.25259/SNI_10_2025
Sadeen Sameer Eid, Arshad Ali, Noman Shah, Amal I Alawadat, Muna AbuHejleh, Issam Al-Bozom, Ghanem Al-Sulaiti
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引用次数: 0

摘要

背景:成人幕部髓母细胞瘤极为罕见,其临床和影像学表现与脑膜瘤相似。本病例报告,与系统回顾,旨在概述临床,影像学,病理和管理策略的成人幕神经管母细胞瘤。病例描述:一名37岁男性患者,表现为头痛、眩晕和呕吐。影像学检查显示一个幕外轴外肿块,最初认为是脑膜瘤。患者随后接受手术切除和放化疗。组织病理学检查最终确定肿块为偏心位置的成人髓母细胞瘤。我们对文献进行了系统的回顾,分析了报道类似病例的四项研究。该分析包括临床和人口统计信息,通过影像学和组织病理学诊断,治疗方法和包括我们自己在内的七个病例的结果。结论:成人幕神经管母细胞瘤是一种极为罕见的肿瘤,可能与脑膜瘤相似,具有重要的临床意义。准确的诊断需要先进的成像技术和组织病理学证实。主要的治疗策略包括最大限度的手术切除,辅以放化疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Adult tentorial medulloblastoma mimicking meningioma: A case report and systematic review.

Background: Tentorial medulloblastomas in adults are exceedingly rare and may clinically and radiologically mimic meningiomas. This case report, with a systematic review, aims to outline the clinical, radiological, pathological, and management strategies for adult tentorial medulloblastoma.

Case description: A 37-year-old male patient presented with headaches, vertigo, and vomiting. Imaging investigations revealed a tentorial extra-axial mass, initially considered a meningioma. The patient subsequently underwent surgical resection followed by chemoradiation. Histopathological examination ultimately identified the mass as an eccentrically located adult medulloblastoma. We conducted a systematic review of the literature, analyzing four studies that reported similar cases. This analysis included clinical and demographic information, diagnosis through imaging and histopathology, treatment methods, and outcomes for seven cases, including our own.

Conclusion: Adult tentorial medulloblastomas are extremely rare tumors that may mimic meningiomas, posing significant clinical challenges. Accurate diagnosis necessitates advanced imaging techniques and histopathological confirmation. The primary treatment strategy involves maximal surgical resection, supplemented by chemoradiotherapy.

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