A Systematic Review of Research Hotspots and Global Trends in Primary Ovarian Insufficiency Research.

Background: The aim of this study was to perform a bibliometric analysis of primary ovarian insufficiency (POI) from 2013 to 2022, to observe global research trends and hotspots in the last ten years, and to provide direction for further research and development of POI in the future.

Method: 4840 articles and reviews related to POI, published from January 1st, 2013 to December 31st, 2022, were retrieved from the Web of Science Core Collection for bibliometric analysis. CiteSpace and VOSviewer were used to analyze countries and regions, organizations, authors, journals, and keywords.

Results: The literature on POI shows an upward trend year by year. In the last ten years, China, the United States, and English have published the largest number of publications in this field with the greatest influence. According to the keyword analysis, the main research hotspots of POI revolve around mesenchymal stem cells.

Conclusion: This study is possibly the first bibliometric analysis that focuses on multiple indicators to analyze the published literature on POI in recent years, hoping to provide some ideas for subsequent authors working in this field and provide new perspectives on research trends and possible hotspots in POI.