门诊关节置换术中接受利多卡因脊髓麻醉患者一过性神经系统症状的发生率

IF 5.1 2区 医学 Q1 ANESTHESIOLOGY
Sara Amaral, Emily Chen, Amanda H Kumar, David B MacLeod, W Michael Bullock, Neil Ray, Erin Manning, Hector Martinez-Wilson, Joshua Dooley, Brian Ohlendorf, Jeff Gadsden
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引用次数: 0

摘要

背景:脊髓麻醉通常用于下肢全关节置换术,但布比卡因引起的长时间运动和交感神经阻滞可延迟恢复。相比之下,利多卡因起效快,持续时间短,是一种有吸引力的替代方案,非常适合门诊下肢手术。它历来与短暂性神经症状(TNS)有关,这是一种自限性但潜在的痛苦疼痛综合征。在较早的研究中报道的TNS发生率差异很大,通常超过20%,这导致利多卡因用于脊髓麻醉的使用减少。目的:本研究旨在评估利多卡因脊髓麻醉后全膝关节和髋关节置换术中多模式镇痛方案的TNS发生率。结果:对1026例接受利多卡因脊髓麻醉的膝关节和髋关节置换术患者进行回顾性分析。我们查询了术后阻滞数据库,其中包括与TNS相关的问题,包括脊柱阻滞解除后新的非手术背部或大腿疼痛的发作以及与TNS相关的任何其他相关症状。在最终分析的1011例患者中,只有2例(0.2%,95% CI 0.02至0.71%)被诊断为TNS,这两例患者均有轻度自限性症状,并在48-72小时内消退。没有观察到长时间的运动或感觉阻滞,马尾综合征或其他显著并发症。该队列中TNS的低发生率与历史报道形成鲜明对比,可能归因于同时给予综合多模式镇痛药,包括对乙酰氨基酚、非甾体抗炎药、静脉注射氯胺酮和地塞米松。结论:在多模式镇痛的情况下,利多卡因脊柱麻醉用于全关节置换术的TNS发生率可以忽略不计。这些发现挑战了历史上关于脊柱利多卡因安全性的担忧,并支持将其作为门诊关节置换手术的可行选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence of transient neurologic symptoms in patients receiving lidocaine spinal anesthesia for outpatient joint arthroplasty.

Background: Spinal anesthesia is commonly administered for lower limb total joint arthroplasty, but the prolonged motor and sympathetic block associated with bupivacaine can delay recovery. In contrast, lidocaine, with its swift onset and intermediate duration, is an attractive alternative that is well-tailored for outpatient lower limb surgery. It has historically been associated with transient neurologic symptoms (TNS), a self-limiting but potentially distressing pain syndrome. The incidence of TNS reported in older studies varies widely, often exceeding 20%, which has led to a decline in the use of lidocaine for spinal anesthesia.

Objective: This study aimed to evaluate the contemporary incidence of TNS following lidocaine spinal anesthesia in the context of an established multimodal analgesic protocol for total knee and hip arthroplasty.

Findings: A retrospective review of 1026 patients undergoing knee and hip arthroplasty with lidocaine spinal anesthesia was conducted. We queried our postoperative block database, which included questions specifically related to TNS, including the onset of new non-surgical back or thigh pain following resolution of the spinal block and any other associated symptoms related to TNS. Of the 1011 patients included in the final analysis, only two (0.2%, 95% CI 0.02 to 0.71%) were diagnosed with TNS, both of whom had mild, self-limited symptoms that resolved within 48-72 hours. No cases of prolonged motor or sensory block, cauda equina syndrome, or other significant complications were observed. The low incidence of TNS in this cohort contrasts sharply with historical reports and may be attributable to concurrent administration of comprehensive multimodal analgesics, including acetaminophen, non-steroidal anti-inflammatory drug, intravenous ketamine, and dexamethasone.

Conclusions: Lidocaine spinal anesthesia for total joint arthroplasty is associated with a negligible incidence of TNS in the setting of multimodal analgesia. These findings challenge historical concerns regarding the safety of spinal lidocaine and support its use as a viable alternative for outpatient joint replacement surgery.

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来源期刊
CiteScore
8.50
自引率
11.80%
发文量
175
审稿时长
6-12 weeks
期刊介绍: Regional Anesthesia & Pain Medicine, the official publication of the American Society of Regional Anesthesia and Pain Medicine (ASRA), is a monthly journal that publishes peer-reviewed scientific and clinical studies to advance the understanding and clinical application of regional techniques for surgical anesthesia and postoperative analgesia. Coverage includes intraoperative regional techniques, perioperative pain, chronic pain, obstetric anesthesia, pediatric anesthesia, outcome studies, and complications. Published for over thirty years, this respected journal also serves as the official publication of the European Society of Regional Anaesthesia and Pain Therapy (ESRA), the Asian and Oceanic Society of Regional Anesthesia (AOSRA), the Latin American Society of Regional Anesthesia (LASRA), the African Society for Regional Anesthesia (AFSRA), and the Academy of Regional Anaesthesia of India (AORA).
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