1999-2020年美国冠状动脉疾病和血脂异常相关死亡率趋势

IF 1.4 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Muhammad R Cheema, Faizan Ahmed, Farman Ali, Zulfiqar Q Baloch, Abdul M Minhas, Faisal Khosa, Nishant Shah
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引用次数: 0

摘要

背景:本研究调查了1999-2020年美国冠状动脉疾病(CAD)和血脂异常合并死亡率的趋势和差异。方法:数据来自CDC WONDER数据库1999-2020年间的多死因档案。ICD-10代码(I20-I25为冠心病,E78为血脂异常)确定了25岁及以上成人中冠心病和血脂异常相关的死亡。统计分析检查了人口和区域死亡率分布。接合点回归分析确定了年龄调整死亡率(AAMR)的趋势,估计了年百分比变化(APC)。结果:1999年至2020年间,美国发生了613,969例冠心病和血脂异常相关死亡。每10万人的AAMR由1999年的6.2上升到2020年的19.0。1999-2005年AAMR急剧上升(APC: 10.2;95% CI: 9.1, 11.3),从2005-2010年增加(APC: 3.3;95% CI: 2.6, 5.0), 2010-2016年稳定(APC: 0.8;95% CI: -0.5, 1.4),并从2016-2019年再次增加(APC: 3.0;95% ci: 1.7, 4.7)。男性占死亡人数的59.8%,AAMR为18.2,而女性为8.7。非西班牙裔(NH)美洲印第安人(13.4)和NH白人(13.3)的aamr最高,其次是NH黑人或非裔美国人(12),西班牙裔或拉丁裔(9.8)和NH亚洲或太平洋岛民(9.1)。中西部地区的AAMR最高(14.1),其次是西部(13.8)、南部(12.2)和东北部(11.3)。非首都地区的aamr(14.7)高于首都地区(12.4)。结论:冠心病合并血脂异常的死亡率正在上升。需要有针对性的干预措施来降低弱势群体的死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Trends in coronary artery disease and dyslipidemia-related mortality in the USA from 1999-2020.

Background: This study examined trends and disparities in USA mortality rates associated with the co-occurrence of coronary artery disease (CAD) and dyslipidemia from 1999-2020.

Methods: Data were obtained from the multiple cause of death files using CDC WONDER, spanning 1999-2020. ICD-10 codes (I20-I25 for CAD and E78 for dyslipidemia) identified CAD and dyslipidemia-related deaths in adults aged 25 and older. Statistical analyses examined demographic and regional mortality distributions. Joinpoint regression analysis determined trends in age-adjusted mortality rates (AAMR), estimating annual percentage changes (APC).

Results: Between 1999 and 2020, 613,969 CAD and dyslipidemia-related deaths occurred in the USA. The AAMR per 100,000 increased from 6.2 in 1999 to 19.0 in 2020. The AAMR rose sharply from 1999-2005 (APC: 10.2; 95% CI: 9.1, 11.3), increased from 2005-2010 (APC: 3.3; 95% CI: 2.6, 5.0), stabilized through 2010-2016 (APC: 0.8; 95% CI: -0.5, 1.4), and increased again from 2016-2019 (APC: 3.0; 95% CI: 1.7, 4.7). Men accounted for 59.8% of deaths, with an AAMR of 18.2, compared to 8.7 for women. Non-Hispanic (NH) American Indian (13.4) and NH white populations (13.3) had the highest AAMRs, followed by NH black or African American (12), Hispanic or Latino (9.8), and NH Asian or Pacific Islanders (9.1). The Midwest had the highest AAMR (14.1), followed by the West (13.8), South (12.2), and Northeast (11.3). Nonmetropolitan areas had higher AAMRs (14.7) compared to metropolitan areas (12.4).

Conclusions: Mortality due to concurrent CAD and dyslipidemia is increasing. Targeted interventions are needed to reduce mortality among vulnerable groups.

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Minerva cardiology and angiology
Minerva cardiology and angiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.60
自引率
18.80%
发文量
118
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