Roberta Albanese, Federica Tomaselli, Claudio Arcudi, Damiano Tambasco
{"title":"加强术前补铁在脂肪腹部成形术：铁羧基麦糖和脂质体铁的比较研究。","authors":"Roberta Albanese, Federica Tomaselli, Claudio Arcudi, Damiano Tambasco","doi":"10.1097/PRS.0000000000012175","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Preoperative anemia is a significant concern in plastic surgery, particularly in procedures such as lipoabdominoplasty, where intraoperative blood loss can impact postoperative recovery. Although oral iron supplementation is a common approach, its limited bioavailability and gastrointestinal intolerance often hinder effective anemia management. This study compares the efficacy of ferric carboxymaltose (FCM) (Ferinject) versus liposomal iron (SiderAL Forte) in optimizing preoperative iron levels and preventing postoperative anemia in patients undergoing 360-degree lipoabdominoplasty.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 44 female patients undergoing lipoabdominoplasty. Patients were divided into 2 groups: group A received oral liposomal iron (14 mg, twice daily) for 1 month preoperatively, and group B received a single intravenous dose of FCM (1000 mg) 72 hours before surgery. Hemoglobin, hematocrit, and ferritin levels were assessed preoperatively, on postoperative day 1, and on postoperative day 7. Statistical comparisons were performed using independent t tests and Pearson correlation analysis.</p><p><strong>Results: </strong>Preoperative hemoglobin and hematocrit levels were comparable between groups. However, postoperative hemoglobin decline was significantly more pronounced in group A ( P < 0.05), whereas group B showed a better preservation of iron stores and faster hematologic recovery. Ferritin levels remained significantly higher in group B throughout the postoperative period ( P < 0.05). No patients required blood transfusions or exhibited symptoms of acute anemia.</p><p><strong>Conclusions: </strong>Intravenous FCM is a superior strategy for preoperative iron optimization in lipoabdominoplasty, ensuring better perioperative stability, faster recovery, and reduced anemia-related complications compared with oral liposomal iron. Integrating this approach into perioperative protocols could enhance surgical outcomes.</p><p><strong>Clinical question/level of evidence: </strong>Therapeutic, III.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":"560-566"},"PeriodicalIF":3.4000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhancing Preoperative Iron Supplemenation in Lipoabdominoplasty: A Comparative Study of Ferric Carboxymaltose and Liposmal Iron.\",\"authors\":\"Roberta Albanese, Federica Tomaselli, Claudio Arcudi, Damiano Tambasco\",\"doi\":\"10.1097/PRS.0000000000012175\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Preoperative anemia is a significant concern in plastic surgery, particularly in procedures such as lipoabdominoplasty, where intraoperative blood loss can impact postoperative recovery. Although oral iron supplementation is a common approach, its limited bioavailability and gastrointestinal intolerance often hinder effective anemia management. This study compares the efficacy of ferric carboxymaltose (FCM) (Ferinject) versus liposomal iron (SiderAL Forte) in optimizing preoperative iron levels and preventing postoperative anemia in patients undergoing 360-degree lipoabdominoplasty.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 44 female patients undergoing lipoabdominoplasty. Patients were divided into 2 groups: group A received oral liposomal iron (14 mg, twice daily) for 1 month preoperatively, and group B received a single intravenous dose of FCM (1000 mg) 72 hours before surgery. Hemoglobin, hematocrit, and ferritin levels were assessed preoperatively, on postoperative day 1, and on postoperative day 7. Statistical comparisons were performed using independent t tests and Pearson correlation analysis.</p><p><strong>Results: </strong>Preoperative hemoglobin and hematocrit levels were comparable between groups. However, postoperative hemoglobin decline was significantly more pronounced in group A ( P < 0.05), whereas group B showed a better preservation of iron stores and faster hematologic recovery. Ferritin levels remained significantly higher in group B throughout the postoperative period ( P < 0.05). No patients required blood transfusions or exhibited symptoms of acute anemia.</p><p><strong>Conclusions: </strong>Intravenous FCM is a superior strategy for preoperative iron optimization in lipoabdominoplasty, ensuring better perioperative stability, faster recovery, and reduced anemia-related complications compared with oral liposomal iron. Integrating this approach into perioperative protocols could enhance surgical outcomes.</p><p><strong>Clinical question/level of evidence: </strong>Therapeutic, III.</p>\",\"PeriodicalId\":20128,\"journal\":{\"name\":\"Plastic and reconstructive surgery\",\"volume\":\" \",\"pages\":\"560-566\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Plastic and reconstructive surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/PRS.0000000000012175\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/5/5 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plastic and reconstructive surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/PRS.0000000000012175","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/5 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"SURGERY","Score":null,"Total":0}
Enhancing Preoperative Iron Supplemenation in Lipoabdominoplasty: A Comparative Study of Ferric Carboxymaltose and Liposmal Iron.
Background: Preoperative anemia is a significant concern in plastic surgery, particularly in procedures such as lipoabdominoplasty, where intraoperative blood loss can impact postoperative recovery. Although oral iron supplementation is a common approach, its limited bioavailability and gastrointestinal intolerance often hinder effective anemia management. This study compares the efficacy of ferric carboxymaltose (FCM) (Ferinject) versus liposomal iron (SiderAL Forte) in optimizing preoperative iron levels and preventing postoperative anemia in patients undergoing 360-degree lipoabdominoplasty.
Methods: A retrospective analysis was conducted on 44 female patients undergoing lipoabdominoplasty. Patients were divided into 2 groups: group A received oral liposomal iron (14 mg, twice daily) for 1 month preoperatively, and group B received a single intravenous dose of FCM (1000 mg) 72 hours before surgery. Hemoglobin, hematocrit, and ferritin levels were assessed preoperatively, on postoperative day 1, and on postoperative day 7. Statistical comparisons were performed using independent t tests and Pearson correlation analysis.
Results: Preoperative hemoglobin and hematocrit levels were comparable between groups. However, postoperative hemoglobin decline was significantly more pronounced in group A ( P < 0.05), whereas group B showed a better preservation of iron stores and faster hematologic recovery. Ferritin levels remained significantly higher in group B throughout the postoperative period ( P < 0.05). No patients required blood transfusions or exhibited symptoms of acute anemia.
Conclusions: Intravenous FCM is a superior strategy for preoperative iron optimization in lipoabdominoplasty, ensuring better perioperative stability, faster recovery, and reduced anemia-related complications compared with oral liposomal iron. Integrating this approach into perioperative protocols could enhance surgical outcomes.
Clinical question/level of evidence: Therapeutic, III.
期刊介绍：
For more than 70 years Plastic and Reconstructive Surgery® has been the one consistently excellent reference for every specialist who uses plastic surgery techniques or works in conjunction with a plastic surgeon. Plastic and Reconstructive Surgery® , the official journal of the American Society of Plastic Surgeons, is a benefit of Society membership, and is also available on a subscription basis.
Plastic and Reconstructive Surgery® brings subscribers up-to-the-minute reports on the latest techniques and follow-up for all areas of plastic and reconstructive surgery, including breast reconstruction, experimental studies, maxillofacial reconstruction, hand and microsurgery, burn repair, cosmetic surgery, as well as news on medicolegal issues. The cosmetic section provides expanded coverage on new procedures and techniques and offers more cosmetic-specific content than any other journal. All subscribers enjoy full access to the Journal''s website, which features broadcast quality videos of reconstructive and cosmetic procedures, podcasts, comprehensive article archives dating to 1946, and additional benefits offered by the newly-redesigned website.
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