Syam Gangadharan Nair, Jittu Alex, Riyas Nazar, John Thayyil John
{"title":"罕见桡骨黄色肉芽肿性骨髓炎表现为病理性骨折1例。","authors":"Syam Gangadharan Nair, Jittu Alex, Riyas Nazar, John Thayyil John","doi":"10.13107/jocr.2025.v15.i04.5462","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Xanthogranulomatous inflammation is a specific form of chronic inflammatory disease histologically characterized by collection of foamy macrophages along with polymorphonuclear leukocytes, activated plasma cells, and lymphocytes of polyclonal origin, in a mosaic-like pattern. The involvement of xanthogranulomatous inflammation of the bone is termed as xanthogranulomatous osteomyelitis (XO). It often presents as a mass-like lesion extending into adjacent structures and so radiological features have little role in pointing to a diagnosis. Definitive diagnosis can only be made by histopathological examination.</p><p><strong>Case report: </strong>This report describes a case of 62-year-old male patient who sustained a pathological fracture of shaft of radius which on evaluation, was diagnosed as XO, its management and 2- year follow-up results. This case report highlights a rare cause of pathological fracture, that is, XO.</p><p><strong>Conclusion: </strong>Clinical examination and radiology have little role in the diagnosis of the condition. Definitive diagnosis is achieved by histopathological examination and the disease has a good prognosis.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 4","pages":"104-107"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981496/pdf/","citationCount":"0","resultStr":"{\"title\":\"A Rare Case of Xanthogranulomatous Osteomyelitis of Radius Presenting as Pathological Fracture - A Case Report.\",\"authors\":\"Syam Gangadharan Nair, Jittu Alex, Riyas Nazar, John Thayyil John\",\"doi\":\"10.13107/jocr.2025.v15.i04.5462\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Xanthogranulomatous inflammation is a specific form of chronic inflammatory disease histologically characterized by collection of foamy macrophages along with polymorphonuclear leukocytes, activated plasma cells, and lymphocytes of polyclonal origin, in a mosaic-like pattern. The involvement of xanthogranulomatous inflammation of the bone is termed as xanthogranulomatous osteomyelitis (XO). It often presents as a mass-like lesion extending into adjacent structures and so radiological features have little role in pointing to a diagnosis. Definitive diagnosis can only be made by histopathological examination.</p><p><strong>Case report: </strong>This report describes a case of 62-year-old male patient who sustained a pathological fracture of shaft of radius which on evaluation, was diagnosed as XO, its management and 2- year follow-up results. This case report highlights a rare cause of pathological fracture, that is, XO.</p><p><strong>Conclusion: </strong>Clinical examination and radiology have little role in the diagnosis of the condition. Definitive diagnosis is achieved by histopathological examination and the disease has a good prognosis.</p>\",\"PeriodicalId\":16647,\"journal\":{\"name\":\"Journal of Orthopaedic Case Reports\",\"volume\":\"15 4\",\"pages\":\"104-107\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981496/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Orthopaedic Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.13107/jocr.2025.v15.i04.5462\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Orthopaedic Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13107/jocr.2025.v15.i04.5462","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Rare Case of Xanthogranulomatous Osteomyelitis of Radius Presenting as Pathological Fracture - A Case Report.
Introduction: Xanthogranulomatous inflammation is a specific form of chronic inflammatory disease histologically characterized by collection of foamy macrophages along with polymorphonuclear leukocytes, activated plasma cells, and lymphocytes of polyclonal origin, in a mosaic-like pattern. The involvement of xanthogranulomatous inflammation of the bone is termed as xanthogranulomatous osteomyelitis (XO). It often presents as a mass-like lesion extending into adjacent structures and so radiological features have little role in pointing to a diagnosis. Definitive diagnosis can only be made by histopathological examination.
Case report: This report describes a case of 62-year-old male patient who sustained a pathological fracture of shaft of radius which on evaluation, was diagnosed as XO, its management and 2- year follow-up results. This case report highlights a rare cause of pathological fracture, that is, XO.
Conclusion: Clinical examination and radiology have little role in the diagnosis of the condition. Definitive diagnosis is achieved by histopathological examination and the disease has a good prognosis.