一种用于高密度接收阵列的线圈通道多路复用器,与MR-linac兼容。

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Tom Bosma, Jan G M Kok, Pim T S Borman, Cornelis A T van den Berg, Martin F Fast
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引用次数: 0

摘要

目标。我们提出了一种原型附加多路复用器,用于将高通道计数接收线圈改装到具有模拟读出链的系统上,例如MR-linac。这种特殊的系统目前配备了两个线圈元件,每个线圈元件只包含四个通道。我们开发了一个基于分时的4:1多路复用板。采用基于cmos的单极双掷开关,以适应快速开关和足够的编码带宽。通过求解基于多路复用器施加的方波调制的方程组,对重建后的线圈通道图像进行分离。该原型在1.5 T扫描仪上进行了图像质量幻象和牛肌肉切片的测试,使用了先前表征的16通道前线圈原型的四个线圈通道。主要的结果。通过复用接收到的图像数据可以可靠地分割成单独的线圈通道图像,并保留线圈的灵敏度图。通道间泄漏保持在- 30db以下。在每个线圈通道中,由于造成数据压缩,与直接数字化相比,信噪比降低了两倍。此外,研究表明,并行成像的g因子在很大程度上不受复用的影响。该多路复用器的成像速度有望提高,因为四倍的通道数增加通常会产生优于信号质量降低的g因子改进。研究人员开发了一种4:1线圈通道附加多路复用器,并在1.5 T的MR读出链中展示了其功能。我们期望该解决方案将为临床MR系统带来显著的成像加速,这些系统受到接收线圈阵列通道数量有限的兼容性的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A coil-channel multiplexer for high-density receive arrays compatible with the MR-linac.

Objective.We present a prototype add-on multiplexer for retro-fitting high-channel count receive coils onto systems with analog readout chains, such as the MR-linac. This particular system is currently equipped with two coil elements, containing only four channels each.Approach.We developed a 4:1 multiplexer board based on time-division. CMOS-based single-pole double-throw switches were used to accommodate for fast switching and adequate encoding bandwidths. Coil-channel images were separated after reconstruction by solving a system of equations based on the square-wave modulation imposed by the multiplexer. The prototype was tested at a 1.5 T scanner on an image-quality phantom and a slice of bovine muscle using four coil channels from a previously characterized 16-channel anterior coil prototype.Main results.The image data received through multiplexing could be reliably divided into separate coil-channel images, preserving the coil sensitivity maps. Leakage between channels remained below -30 dB. In each coil channel the signal-to-noise ratio was penalized by a factor of two compared to direct digitization due to the inflicted data compression. Furthermore, it was shown that theg-factor for parallel imaging remained largely unaffected by multiplexing. Imaging speedup is expected with this multiplexer, since a fourfold channel-count increase typically yieldsg-factor improvements that are superior to the signal-quality reduction.Significance.A 4:1 coil-channel add-on multiplexer was developed and its functionality demonstrated in the MR readout chain at 1.5 T. We expect that this solution will enable significant imaging speedup for clinical MR systems that suffer from compatibility with a limited number of channels for the receive coil array.

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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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