15岁男性股骨远端骨肉瘤的综合治疗:多学科方法和长期随访。

Alok Chandra Agrawal, Harshal Suhas Sakale, Roshan Lal Goyal, Akash Mishra, Punit Gaurav, Anupam Pradip Inamdar
{"title":"15岁男性股骨远端骨肉瘤的综合治疗:多学科方法和长期随访。","authors":"Alok Chandra Agrawal, Harshal Suhas Sakale, Roshan Lal Goyal, Akash Mishra, Punit Gaurav, Anupam Pradip Inamdar","doi":"10.13107/jocr.2025.v15.i04.5450","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>This comprehensive case report highlights the intricate diagnosis and multidisciplinary management of distal femur osteosarcoma in a 15-year-old male. Osteosarcoma is a rare and aggressive form of bone cancer, particularly affecting adolescents and young adults. The significance of this case lies in the detailed description of the diagnostic process, treatment strategy, and successful outcome, which may contribute valuable insights to the existing literature. While numerous case reports on osteosarcoma exist, this report offers unique insights into the management approach and outcome of distal femur osteosarcoma, potentially providing guidance for clinicians facing similar cases in the future.</p><p><strong>Case report: </strong>The patient in question is a 15-year-old male, whose ethnic background was not specified. He presented with symptoms suggestive of distal femur osteosarcoma, including localized bone pain, swelling, and limited range of motion in the affected knee joint. Radiological investigations confirmed the presence of a tumor in the distal femur, prompting further evaluation. Pathological markers and histopathological examination confirmed the diagnosis of osteosarcoma. Pre-operative neoadjuvant chemotherapy was administered to optimize conditions for surgical intervention.</p><p><strong>Conclusion: </strong>This case report underscores the importance of a comprehensive, multidisciplinary approach in the management of distal femur osteosarcoma. The successful outcome, marked by complete tumor excision, reconstruction using autologous fibula graft, and restoration of knee function, highlights the efficacy of the chosen treatment strategy. Furthermore, this report may serve as a valuable resource for clinicians specializing in orthopedic oncology, providing insights into optimal treatment protocols and post-operative care for similar cases. In addition, it contributes to the broader field of oncology by advancing our understanding of osteosarcoma management and emphasizing the importance of individualized treatment plans tailored to the patient's specific needs.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 4","pages":"74-79"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981506/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comprehensive Management of Distal Femur Osteosarcoma in a 15-year-old Male: A Multidisciplinary Approach and Long-term Follow-up.\",\"authors\":\"Alok Chandra Agrawal, Harshal Suhas Sakale, Roshan Lal Goyal, Akash Mishra, Punit Gaurav, Anupam Pradip Inamdar\",\"doi\":\"10.13107/jocr.2025.v15.i04.5450\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>This comprehensive case report highlights the intricate diagnosis and multidisciplinary management of distal femur osteosarcoma in a 15-year-old male. Osteosarcoma is a rare and aggressive form of bone cancer, particularly affecting adolescents and young adults. The significance of this case lies in the detailed description of the diagnostic process, treatment strategy, and successful outcome, which may contribute valuable insights to the existing literature. While numerous case reports on osteosarcoma exist, this report offers unique insights into the management approach and outcome of distal femur osteosarcoma, potentially providing guidance for clinicians facing similar cases in the future.</p><p><strong>Case report: </strong>The patient in question is a 15-year-old male, whose ethnic background was not specified. He presented with symptoms suggestive of distal femur osteosarcoma, including localized bone pain, swelling, and limited range of motion in the affected knee joint. Radiological investigations confirmed the presence of a tumor in the distal femur, prompting further evaluation. Pathological markers and histopathological examination confirmed the diagnosis of osteosarcoma. Pre-operative neoadjuvant chemotherapy was administered to optimize conditions for surgical intervention.</p><p><strong>Conclusion: </strong>This case report underscores the importance of a comprehensive, multidisciplinary approach in the management of distal femur osteosarcoma. The successful outcome, marked by complete tumor excision, reconstruction using autologous fibula graft, and restoration of knee function, highlights the efficacy of the chosen treatment strategy. Furthermore, this report may serve as a valuable resource for clinicians specializing in orthopedic oncology, providing insights into optimal treatment protocols and post-operative care for similar cases. In addition, it contributes to the broader field of oncology by advancing our understanding of osteosarcoma management and emphasizing the importance of individualized treatment plans tailored to the patient's specific needs.</p>\",\"PeriodicalId\":16647,\"journal\":{\"name\":\"Journal of Orthopaedic Case Reports\",\"volume\":\"15 4\",\"pages\":\"74-79\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981506/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Orthopaedic Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.13107/jocr.2025.v15.i04.5450\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Orthopaedic Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.13107/jocr.2025.v15.i04.5450","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

简介:本综合病例报告强调了一名15岁男性股骨远端骨肉瘤的复杂诊断和多学科治疗。骨肉瘤是一种罕见的侵袭性骨癌,尤其影响青少年和年轻人。本病例的意义在于对诊断过程、治疗策略和成功结果的详细描述,这可能为现有文献提供有价值的见解。虽然有许多关于骨肉瘤的病例报道,但本报告对股骨远端骨肉瘤的治疗方法和结果提供了独特的见解,可能为临床医生今后面对类似病例提供指导。病例报告:患者为15岁男性,种族背景不详。患者表现出提示股骨远端骨肉瘤的症状,包括局部骨痛、肿胀和受影响膝关节活动范围受限。放射学检查证实股骨远端存在肿瘤,提示进一步评估。病理标记和组织病理学检查证实了骨肉瘤的诊断。术前给予新辅助化疗以优化手术干预条件。结论:本病例报告强调了综合多学科方法治疗股骨远端骨肉瘤的重要性。成功的结果,以肿瘤完全切除、自体腓骨移植重建和膝关节功能恢复为标志,突出了所选治疗策略的有效性。此外,本报告可作为骨科肿瘤学专业临床医生的宝贵资源,为类似病例的最佳治疗方案和术后护理提供见解。此外,它通过提高我们对骨肉瘤管理的理解和强调针对患者特定需求量身定制的个性化治疗计划的重要性,为肿瘤学更广泛的领域做出了贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comprehensive Management of Distal Femur Osteosarcoma in a 15-year-old Male: A Multidisciplinary Approach and Long-term Follow-up.

Introduction: This comprehensive case report highlights the intricate diagnosis and multidisciplinary management of distal femur osteosarcoma in a 15-year-old male. Osteosarcoma is a rare and aggressive form of bone cancer, particularly affecting adolescents and young adults. The significance of this case lies in the detailed description of the diagnostic process, treatment strategy, and successful outcome, which may contribute valuable insights to the existing literature. While numerous case reports on osteosarcoma exist, this report offers unique insights into the management approach and outcome of distal femur osteosarcoma, potentially providing guidance for clinicians facing similar cases in the future.

Case report: The patient in question is a 15-year-old male, whose ethnic background was not specified. He presented with symptoms suggestive of distal femur osteosarcoma, including localized bone pain, swelling, and limited range of motion in the affected knee joint. Radiological investigations confirmed the presence of a tumor in the distal femur, prompting further evaluation. Pathological markers and histopathological examination confirmed the diagnosis of osteosarcoma. Pre-operative neoadjuvant chemotherapy was administered to optimize conditions for surgical intervention.

Conclusion: This case report underscores the importance of a comprehensive, multidisciplinary approach in the management of distal femur osteosarcoma. The successful outcome, marked by complete tumor excision, reconstruction using autologous fibula graft, and restoration of knee function, highlights the efficacy of the chosen treatment strategy. Furthermore, this report may serve as a valuable resource for clinicians specializing in orthopedic oncology, providing insights into optimal treatment protocols and post-operative care for similar cases. In addition, it contributes to the broader field of oncology by advancing our understanding of osteosarcoma management and emphasizing the importance of individualized treatment plans tailored to the patient's specific needs.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
128
审稿时长
30 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信