评估髋关节镜下静脉血栓栓塞风险:青少年和成人的倾向匹配比较。

IF 1.5 3区 医学 Q3 ORTHOPEDICS
Journal of Pediatric Orthopaedics Pub Date : 2025-09-01 Epub Date: 2025-04-16 DOI:10.1097/BPO.0000000000002987
Mehul M Mittal, Katalina V Acevedo, Tiffany M Lee, Aaron Singh, Pooya Hosseinzadeh
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引用次数: 0

摘要

背景:髋关节镜检查是一种常见的手术在青少年髋关节病理。然而,在这一人群中静脉血栓栓塞(VTE)事件的数据有限,导致关于适当预防VTE的指导很少,目前的大部分指导都是从成人人群中推断出来的。因此,本研究旨在评估青少年人群中静脉血栓栓塞的总体发生率,并将这些发生率与接受髋关节镜检查的成年患者进行比较。方法:这项回顾性队列研究的数据来自TriNetX平台2003年1月1日至2024年3月1日。年龄在13至18岁之间的青少年患者与接受髋关节镜检查的成年患者(19岁及以上)相匹配,包括性别、吸烟、口服避孕药、糖尿病和超重/肥胖。术后90天内观察深静脉血栓形成(DVT)或肺栓塞(PE)。计算并比较各组间的总发病率。结果有统计学意义:共有3655例患者成功匹配,青少年队列平均年龄为16岁,成人队列平均年龄为35岁。队列间DVT的总体发生率相似,青少年患者为1%,成人患者为0.9% (RR: 0.892;95% ci: 0.559-1.423;P = 0.63)。所有静脉血栓栓塞事件(合并DVT和PE)在青少年患者中也相似,分别为1.1%和1.0% (RR: 0.925;95% ci: 0.593-1.443;P = 0.73)。结论:本研究发现青少年和成人髋关节镜患者的静脉血栓栓塞无显著差异。青少年患者静脉血栓栓塞的总体发生率相对较高,为1.1%,这表明对静脉血栓栓塞的额外关注和潜在的化学预防可能是有必要的。证据等级:iii级——病例对照研究或回顾性队列研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessing Venous Thromboembolism Risk in Hip Arthroscopy: A Propensity-matched Comparison of Adolescents and Adults.

Background: Hip arthroscopy is a commonly performed procedure in adolescents with hip pathology. However, there is limited data on venous thromboembolism (VTE) events in this population, resulting in minimal guidance on appropriate VTE prophylaxis, with the bulk of current guidance extrapolated from the adult population. Therefore, this study aims to assess overall rates of VTE in the adolescent population as well as compare these rates to a matched cohort of adult patients undergoing hip arthroscopy.

Methods: This retrospective cohort study drew data from the TriNetX platform between January 1, 2003 and March 1, 2024. Adolescent patients, ages 13 to 18, were matched to adult patients (19 and older) undergoing hip arthroscopy, accounting for sex, tobacco use, oral contraceptive use, diabetes mellitus, and overweight/obesity. Outcomes of interest were deep vein thrombosis (DVT) or pulmonary embolism (PE) within 90 days after the procedure. Overall rates were calculated and compared between cohorts. Statistical significance was set at P <0.01.

Results: A total of 3655 patients were successfully matched with a mean age of 16 in the adolescent cohort and 35 in the adult cohort. The overall rates of DVT were similar between cohorts, at 1% for adolescent patients and 0.9% for adults (RR: 0.892; 95% CI: 0.559-1.423; P =0.63). All VTE events (combined DVT and PE) were also similar at 1.1% for adolescent patients and 1.0% in adults (RR: 0.925; 95% CI: 0.593-1.443; P =0.73).

Conclusion: This study found no significant difference in VTE between adolescent and adult patients undergoing hip arthroscopy. The overall rate of VTE was relatively high in adolescent patients, at 1.1%, suggesting additional attention to VTE and potential chemoprophylaxis may be warranted in select patients.

Level of evidence: Level III-case-control study or retrospective cohort study.

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来源期刊
CiteScore
3.30
自引率
17.60%
发文量
512
审稿时长
6 months
期刊介绍: ​Journal of Pediatric Orthopaedics is a leading journal that focuses specifically on traumatic injuries to give you hands-on on coverage of a fast-growing field. You''ll get articles that cover everything from the nature of injury to the effects of new drug therapies; everything from recommendations for more effective surgical approaches to the latest laboratory findings.
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