Marie Renaudier, Vincent Degos, Gianluca Pisanu, Benjamin Granger, Lamine Abdennour, Caroline Tabillon, Dany Hijazi, Anne-Laure Boch, Bertrand Mathon, Frédéric Clarençon, Eimad Shotar, Louis Puybasset, Rémy Bernard, Alice Jacquens
{"title":"蛛网膜下腔出血的18年治疗趋势和结果：单中心经验。","authors":"Marie Renaudier, Vincent Degos, Gianluca Pisanu, Benjamin Granger, Lamine Abdennour, Caroline Tabillon, Dany Hijazi, Anne-Laure Boch, Bertrand Mathon, Frédéric Clarençon, Eimad Shotar, Louis Puybasset, Rémy Bernard, Alice Jacquens","doi":"10.1007/s12028-025-02268-3","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Although subarachnoid hemorrhage-related mortality has decreased in recent years due to improvements in treatment, data on the evolution of 1-year functional outcomes after subarachnoid hemorrhage are lacking. The objective of this study was to evaluate the evolution of patient management and their functional outcomes 1 year after subarachnoid hemorrhage over time in a single high-volume neurosurgical intensive care unit.</p><p><strong>Methods: </strong>In this observational retrospective study, all consecutive patients with aneurysmal subarachnoid hemorrhage admitted to our neurosurgical intensive care unit between 2002 and 2019 were included. A poor functional outcome was defined as a modified Rankin Scale score of 4-6. Linear regressions were performed, and relative risk reductions of a poor functional outcome were calculated.</p><p><strong>Results: </strong>Between 2002 and 2019, 1556 patients were included, of whom 329 (21%) had a poor functional outcome. Over time, the percentage of coiling procedures (p = 0.004) increased, and the percentage of delayed cerebral ischemia (p = 0.03) decreased. One-year mortality decreased over time (p < 0.001), whereas 1-year functional outcome improved (p = 0.002), with a relative risk reduction of poor functional outcomes of 38% (17-54%).</p><p><strong>Conclusions: </strong>The 1-year functional outcome of patients with subarachnoid hemorrhage improved between 2002 and 2019, and mortality decreased.</p>","PeriodicalId":19118,"journal":{"name":"Neurocritical Care","volume":" ","pages":"598-606"},"PeriodicalIF":3.6000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Eighteen-Year Trends in Subarachnoid Hemorrhage Management and Outcomes: A Single-Center Experience.\",\"authors\":\"Marie Renaudier, Vincent Degos, Gianluca Pisanu, Benjamin Granger, Lamine Abdennour, Caroline Tabillon, Dany Hijazi, Anne-Laure Boch, Bertrand Mathon, Frédéric Clarençon, Eimad Shotar, Louis Puybasset, Rémy Bernard, Alice Jacquens\",\"doi\":\"10.1007/s12028-025-02268-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Although subarachnoid hemorrhage-related mortality has decreased in recent years due to improvements in treatment, data on the evolution of 1-year functional outcomes after subarachnoid hemorrhage are lacking. The objective of this study was to evaluate the evolution of patient management and their functional outcomes 1 year after subarachnoid hemorrhage over time in a single high-volume neurosurgical intensive care unit.</p><p><strong>Methods: </strong>In this observational retrospective study, all consecutive patients with aneurysmal subarachnoid hemorrhage admitted to our neurosurgical intensive care unit between 2002 and 2019 were included. A poor functional outcome was defined as a modified Rankin Scale score of 4-6. Linear regressions were performed, and relative risk reductions of a poor functional outcome were calculated.</p><p><strong>Results: </strong>Between 2002 and 2019, 1556 patients were included, of whom 329 (21%) had a poor functional outcome. Over time, the percentage of coiling procedures (p = 0.004) increased, and the percentage of delayed cerebral ischemia (p = 0.03) decreased. One-year mortality decreased over time (p < 0.001), whereas 1-year functional outcome improved (p = 0.002), with a relative risk reduction of poor functional outcomes of 38% (17-54%).</p><p><strong>Conclusions: </strong>The 1-year functional outcome of patients with subarachnoid hemorrhage improved between 2002 and 2019, and mortality decreased.</p>\",\"PeriodicalId\":19118,\"journal\":{\"name\":\"Neurocritical Care\",\"volume\":\" \",\"pages\":\"598-606\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurocritical Care\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s12028-025-02268-3\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/28 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurocritical Care","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12028-025-02268-3","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/28 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Eighteen-Year Trends in Subarachnoid Hemorrhage Management and Outcomes: A Single-Center Experience.
Background: Although subarachnoid hemorrhage-related mortality has decreased in recent years due to improvements in treatment, data on the evolution of 1-year functional outcomes after subarachnoid hemorrhage are lacking. The objective of this study was to evaluate the evolution of patient management and their functional outcomes 1 year after subarachnoid hemorrhage over time in a single high-volume neurosurgical intensive care unit.
Methods: In this observational retrospective study, all consecutive patients with aneurysmal subarachnoid hemorrhage admitted to our neurosurgical intensive care unit between 2002 and 2019 were included. A poor functional outcome was defined as a modified Rankin Scale score of 4-6. Linear regressions were performed, and relative risk reductions of a poor functional outcome were calculated.
Results: Between 2002 and 2019, 1556 patients were included, of whom 329 (21%) had a poor functional outcome. Over time, the percentage of coiling procedures (p = 0.004) increased, and the percentage of delayed cerebral ischemia (p = 0.03) decreased. One-year mortality decreased over time (p < 0.001), whereas 1-year functional outcome improved (p = 0.002), with a relative risk reduction of poor functional outcomes of 38% (17-54%).
Conclusions: The 1-year functional outcome of patients with subarachnoid hemorrhage improved between 2002 and 2019, and mortality decreased.
期刊介绍：
Neurocritical Care is a peer reviewed scientific publication whose major goal is to disseminate new knowledge on all aspects of acute neurological care. It is directed towards neurosurgeons, neuro-intensivists, neurologists, anesthesiologists, emergency physicians, and critical care nurses treating patients with urgent neurologic disorders. These are conditions that may potentially evolve rapidly and could need immediate medical or surgical intervention. Neurocritical Care provides a comprehensive overview of current developments in intensive care neurology, neurosurgery and neuroanesthesia and includes information about new therapeutic avenues and technological innovations. Neurocritical Care is the official journal of the Neurocritical Care Society.
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