一种新的1型糖尿病儿童随访模型导致更高的血糖控制。

IF 3.9 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Pediatric Diabetes Pub Date : 2025-01-07 eCollection Date: 2025-01-01 DOI:10.1155/pedi/6920068
Julia Vonasek, Isabelle M Larsen, Amar Nikontovic, Camilla Maria Thorvig
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引用次数: 0

摘要

背景:儿童1型糖尿病(T1D)血糖控制不良导致糖尿病并发症的风险较高。在北丹麦地区医院的儿科,2016年只有三分之一的糖尿病患儿得到了良好的调节,定义为HbA1c不超过58 mmol/mol(7.5%)。因此,我们开发了一种新的随访模型,以增加调节良好的T1Ds儿童的比例。本研究的目的是评估调节不良糖尿病的标准化随访模型对平均HbA1c的影响。方法:所有0 ~ 18岁T1Ds患儿均为研究对象。如果HbA1c大于58 mmol/mol(7.5%),则建立了一种新的标准化随访模型,在此模型中,儿童将更密切地随访直到血糖控制改善。结果:在参考年,只有三分之一的糖尿病儿童调节良好,19%调节不良(HbA1c大于75 mmol/mol(9.0%))。在全面实施该模型后,三分之二的儿童患有控制良好的糖尿病,只有少数人患有控制不良的糖尿病。从参考年到模型完全实施后的几年,平均HbA1c下降了近10 mmol/mol(或0.8%)。结论:这种不良调节糖尿病的随访模型增加了我们临床中调节良好的糖尿病儿童的比例,并显著降低了平均HbA1c。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel Follow-Up Model for Type 1 Diabetes in Children Leads to Higher Glycemic Control.

Background: Poor glycemic control in type 1 diabetes (T1D) in children leads to a higher risk of diabetic complications. In the pediatric department at the North Denmark Regional Hospital, only one-third of all children with diabetes were well-regulated, defined as HbA1c no more than 58 mmol/mol (7.5%), in 2016. Therefore, a novel follow-up model was developed to increase the proportion of children with well-regulated T1Ds. The aim of this study was to evaluate the effect of a standardized follow-up model for poorly regulated diabetes on mean HbA1c. Methods: All children aged 0-18 with T1Ds were included in this study. A novel standardized follow-up model was developed if HbA1c was greater than 58 mmol/mol (7.5%), in which children were followed more closely until improvement in glycemic control. Results: In the reference year, only one-third of children with diabetes were well-regulated and 19% were poorly regulated (HbA1c greater than 75 mmol/mol (9.0%)). After fully implementing the model, two-thirds of the children had well-regulated diabetes, and only a few percent had poorly regulated diabetes. The mean HbA1c decreased by almost 10 mmol/mol (or 0.8%) from the reference year to the following years when the model was fully implemented. Conclusion: This follow-up model for poorly regulated diabetes increased the fraction of children with well-regulated diabetes in our clinic and significantly decreased mean HbA1c.

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来源期刊
Pediatric Diabetes
Pediatric Diabetes 医学-内分泌学与代谢
CiteScore
6.60
自引率
14.70%
发文量
141
审稿时长
4-8 weeks
期刊介绍: Pediatric Diabetes is a bi-monthly journal devoted to disseminating new knowledge relating to the epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes in childhood and adolescence. The aim of the journal is to become the leading vehicle for international dissemination of research and practice relating to diabetes in youth. Papers are considered for publication based on the rigor of scientific approach, novelty, and importance for understanding mechanisms involved in the epidemiology and etiology of this disease, especially its molecular, biochemical and physiological aspects. Work relating to the clinical presentation, course, management and outcome of diabetes, including its physical and emotional sequelae, is considered. In vitro studies using animal or human tissues, whole animal and clinical studies in humans are also considered. The journal reviews full-length papers, preliminary communications with important new information, clinical reports, and reviews of major topics. Invited editorials, commentaries, and perspectives are a regular feature. The editors, based in the USA, Europe, and Australasia, maintain regular communications to assure rapid turnaround time of submitted manuscripts.
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