{"title":"抑郁症状、躯体症状、血清素水平与赌博障碍之间的关系：一项病例对照研究","authors":"Jong Min Choi, Eun Jin Lee","doi":"10.3928/02793695-20250415-03","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The current study compares depressive symptoms, physical symptoms, and serotonin levels between individuals with gambling disorder (GD) and healthy controls (HC), investigates their relationship, and identifies factors that predict the development of GD.</p><p><strong>Method: </strong>A case-control study with purposive convenience sampling was conducted using data from GD (<i>n</i> = 76) and HC (<i>n</i> = 56) groups.</p><p><strong>Results: </strong>Increased depressive symptoms were associated with greater physical symptoms (<i>r</i> = 0.70, <i>p</i> < 0.001) and problem gambling severity (<i>r</i> = 0.37, <i>p</i> = 0.001). Decreased serotonin levels suggest a potential depressive disorder; however, not all individuals had lower serotonin levels, indicating emotionally vulnerable subgroups. Increased serotonin levels correlated with restlessness, which was associated with problem gambling (<i>r</i> = 0.31, <i>p</i> = 0.006). Decreased problem gambling severity was linked to increased alcohol use (<i>r</i> = -0.29, <i>p</i> = 0.012).</p><p><strong>Conclusion: </strong>Results indicate a correlation among depressive symptoms, physical symptoms, and serotonin imbalance in individuals with GD.</p>","PeriodicalId":50071,"journal":{"name":"Journal of Psychosocial Nursing and Mental Health Services","volume":" ","pages":"39-48"},"PeriodicalIF":1.1000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association Among Depressive Symptoms, Physical Symptoms, Serotonin Levels, and Gambling Disorder: A Case-Control Study.\",\"authors\":\"Jong Min Choi, Eun Jin Lee\",\"doi\":\"10.3928/02793695-20250415-03\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The current study compares depressive symptoms, physical symptoms, and serotonin levels between individuals with gambling disorder (GD) and healthy controls (HC), investigates their relationship, and identifies factors that predict the development of GD.</p><p><strong>Method: </strong>A case-control study with purposive convenience sampling was conducted using data from GD (<i>n</i> = 76) and HC (<i>n</i> = 56) groups.</p><p><strong>Results: </strong>Increased depressive symptoms were associated with greater physical symptoms (<i>r</i> = 0.70, <i>p</i> < 0.001) and problem gambling severity (<i>r</i> = 0.37, <i>p</i> = 0.001). Decreased serotonin levels suggest a potential depressive disorder; however, not all individuals had lower serotonin levels, indicating emotionally vulnerable subgroups. Increased serotonin levels correlated with restlessness, which was associated with problem gambling (<i>r</i> = 0.31, <i>p</i> = 0.006). Decreased problem gambling severity was linked to increased alcohol use (<i>r</i> = -0.29, <i>p</i> = 0.012).</p><p><strong>Conclusion: </strong>Results indicate a correlation among depressive symptoms, physical symptoms, and serotonin imbalance in individuals with GD.</p>\",\"PeriodicalId\":50071,\"journal\":{\"name\":\"Journal of Psychosocial Nursing and Mental Health Services\",\"volume\":\" \",\"pages\":\"39-48\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Psychosocial Nursing and Mental Health Services\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3928/02793695-20250415-03\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/23 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"NURSING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Psychosocial Nursing and Mental Health Services","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3928/02793695-20250415-03","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/23 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"NURSING","Score":null,"Total":0}
引用次数: 0
摘要
目的：本研究比较了赌博障碍（GD）和健康对照（HC）的抑郁症状、身体症状和血清素水平，探讨了它们之间的关系，并确定了预测GD发展的因素。方法：采用有目的方便抽样的病例对照研究，采用GD组（76例）和HC组（56例）的资料。结果：加重的抑郁症状与加重的身体症状（r = 0.70, p < 0.001）和问题赌博严重程度（r = 0.37, p = 0.001）相关。血清素水平下降提示有潜在的抑郁症；然而，并不是所有人的血清素水平都较低，这表明情绪脆弱的亚群体。血清素水平升高与不安相关，而不安与赌博问题有关（r = 0.31, p = 0.006）。问题赌博严重程度降低与酒精使用增加有关（r = -0.29, p = 0.012）。结论：结果表明GD患者抑郁症状、躯体症状和血清素失衡之间存在相关性。[社会心理护理与精神卫生服务杂志，xx(x), xx-xx.]
Association Among Depressive Symptoms, Physical Symptoms, Serotonin Levels, and Gambling Disorder: A Case-Control Study.
Purpose: The current study compares depressive symptoms, physical symptoms, and serotonin levels between individuals with gambling disorder (GD) and healthy controls (HC), investigates their relationship, and identifies factors that predict the development of GD.
Method: A case-control study with purposive convenience sampling was conducted using data from GD (n = 76) and HC (n = 56) groups.
Results: Increased depressive symptoms were associated with greater physical symptoms (r = 0.70, p < 0.001) and problem gambling severity (r = 0.37, p = 0.001). Decreased serotonin levels suggest a potential depressive disorder; however, not all individuals had lower serotonin levels, indicating emotionally vulnerable subgroups. Increased serotonin levels correlated with restlessness, which was associated with problem gambling (r = 0.31, p = 0.006). Decreased problem gambling severity was linked to increased alcohol use (r = -0.29, p = 0.012).
Conclusion: Results indicate a correlation among depressive symptoms, physical symptoms, and serotonin imbalance in individuals with GD.
期刊介绍：
The Journal of Psychosocial Nursing and Mental Health Services is a peer-reviewed, monthly journal for psychosocial and mental health nurses in a variety of community and institutional settings. For more than 50 years, the Journal has provided the most up-to-date, practical information available for today’s psychosocial-mental health nurse, including short contributions about psychopharmacology, mental health care of older adults, addictive behaviors and diagnoses, and child/adolescent disorders and issues. Begin to explore the Journal and all of its great benefits such as:
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