晚期狼疮性肾炎新诊断1例报告。

IF 2.4 4区 医学 Q2 UROLOGY & NEPHROLOGY
Nephrology Pub Date : 2025-05-01 DOI:10.1111/nep.70037
Umesha Pathmanathan, Sivasaaini Sivakumaran, Jade Eccles-Smith, Ann-Maree Craven, Jill Parkes Smith, Prianka Puri, Kirsten Hepburn
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引用次数: 0

摘要

新发狼疮肾炎(LN)提出了诊断和管理的挑战,在怀孕期间。这在土著人群中更为相关,那里的患病率更高,临床表型往往更严重。我们报告一例30岁的G3P2土著女性,生活在偏远的昆士兰州,在妊娠30周出现肾病综合征。临床诊断为V级LN,由于母婴风险,未行肾活检,并经验性使用类固醇和疾病改进剂治疗,效果良好。她保持血压正常,胎儿生长正常,并在37周时生下了一个健康的男婴。治疗开始9周后进行的肾活检显示为II级LN,可能代表在临床症状改善的情况下耀斑消退。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New Diagnosis of Lupus Nephritis in the Third Trimester-A Case Report.

New-onset lupus nephritis (LN) poses a diagnostic and management challenge during pregnancy. This is more pertinent in the indigenous population, where the prevalence is higher, and the clinical phenotype tends to be more severe. We report the case of a 30-year-old G3P2 indigenous female, living in remote Queensland, with a late presentation of nephrotic syndrome at 30 weeks gestation. A clinical diagnosis of Class V LN was made without a kidney biopsy due to maternal and foetal risk, and she was empirically treated with steroids and disease-modifying agents to good effect. She remained normotensive with appropriate foetal growth and delivered a healthy male infant at 37 weeks. A renal biopsy taken 9 weeks after commencement of therapy demonstrated Class II LN, likely representing a resolving flare in the presence of improved clinical symptoms.

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来源期刊
Nephrology
Nephrology 医学-泌尿学与肾脏学
CiteScore
4.50
自引率
4.00%
发文量
128
审稿时长
4-8 weeks
期刊介绍: Nephrology is published eight times per year by the Asian Pacific Society of Nephrology. It has a special emphasis on the needs of Clinical Nephrologists and those in developing countries. The journal publishes reviews and papers of international interest describing original research concerned with clinical and experimental aspects of nephrology.
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