{"title":"复杂碳水化合物的化学合成。","authors":"Paul Kosma","doi":"10.1007/164_2025_747","DOIUrl":null,"url":null,"abstract":"<p><p>The chapter provides a brief overview on current methodologies for the assembly of complex oligosaccharides by chemical synthesis. Following an introductory section describing the major factors and variables involved in glycosylation reactions, select examples for advanced approaches towards mammalian and bacterial glycans are discussed illustrating recent progress in the field of glycochemistry.</p>","PeriodicalId":12859,"journal":{"name":"Handbook of experimental pharmacology","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chemical Synthesis of Complex Carbohydrates.\",\"authors\":\"Paul Kosma\",\"doi\":\"10.1007/164_2025_747\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The chapter provides a brief overview on current methodologies for the assembly of complex oligosaccharides by chemical synthesis. Following an introductory section describing the major factors and variables involved in glycosylation reactions, select examples for advanced approaches towards mammalian and bacterial glycans are discussed illustrating recent progress in the field of glycochemistry.</p>\",\"PeriodicalId\":12859,\"journal\":{\"name\":\"Handbook of experimental pharmacology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Handbook of experimental pharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/164_2025_747\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Handbook of experimental pharmacology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/164_2025_747","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
The chapter provides a brief overview on current methodologies for the assembly of complex oligosaccharides by chemical synthesis. Following an introductory section describing the major factors and variables involved in glycosylation reactions, select examples for advanced approaches towards mammalian and bacterial glycans are discussed illustrating recent progress in the field of glycochemistry.
期刊介绍:
The Handbook of Experimental Pharmacology is one of the most authoritative and influential book series in pharmacology. It provides critical and comprehensive discussions of the most significant areas of pharmacological research, written by leading international authorities. Each volume in the series represents the most informative and contemporary account of its subject available, making it an unrivalled reference source.