新西兰坎特伯雷地区类风湿关节炎的发病率、患病率和死亡率。

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Hamish J Farquhar, Tania Huria, Lutz Beckert, Christopher M A Frampton, Janine Haslett, Lisa K Stamp
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引用次数: 0

摘要

背景:关于坎特伯雷地区类风湿关节炎(RA)发病率的研究相对较少,之前也没有研究将新西兰奥特罗阿地区类风湿关节炎的死亡率与普通人群进行比较。目的:了解新西兰坎特伯雷地区RA的发病率、患病率和死亡率。方法:对2006年1月1日至2008年12月31日(第1期)和2011年1月1日至2013年12月31日(第2期)期间在基督城医院风湿病科就诊的患者的临床记录进行回顾,以确定符合2010年美国风湿病学会/欧洲抗风湿病联盟RA分类标准的患者。还审查了私营部门风湿病学家治疗的患者的医疗记录。计算各时间段的流行率和年平均发病率。总人口的患病率和发病率根据2013年全国人口普查的常住人口进行年龄和性别调整。计算与一般人群相比的标准化死亡率(SMRs)。结果:第一阶段的年发病率为24.40 / 10万(95%可信区间(CI): 21.36-27.43),第二阶段的年发病率为22.06 / 10万(95% CI: 19.32-24.81)。第1期的发病率为442.65 / 10万(95% CI: 420.08-465.04),第2期为448.66 / 10万(95% CI: 427.31-470.01)。突发RA个体的全因SMR为1.25 (95% CI: 0.95-1.60)。第一阶段所有流行RA的SMR为2.01 (95% CI: 1.85-2.19),第二阶段的SMR为1.87 (95% CI: 1.69-2.06)。结论:坎特伯雷人群RA发病率与其他地区相当。所有流行类风湿性关节炎患者的死亡率大约是一般人群的两倍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence, prevalence and mortality of rheumatoid arthritis in Canterbury, Aotearoa New Zealand.

Background: There is relatively little research regarding the frequency of rheumatoid arthritis (RA) in Canterbury and no previous studies comparing the mortality of RA in Aotearoa New Zealand to a general population.

Aims: To determine the incidence, prevalence and mortality of RA in Canterbury, Aotearoa New Zealand.

Methods: Clinical records of persons attending the Christchurch Hospital rheumatology service between 1 January 2006 and 31 December 2008 (Period 1) and between 1 January 2011 and 31 December 2013 (Period 2) were reviewed to identify individuals who met the 2010 American College of Rheumatology/European League Against Rheumatism RA classification criteria. Medical records for persons treated by private sector rheumatologists were also reviewed. The period prevalence and average annual incidence for each time period were calculated. Prevalence and incidence rates for the total population were age- and sex-adjusted based on the usually resident population from the 2013 national Census. Standardised mortality ratios (SMRs) compared to the general population were calculated.

Results: The annual incidence was 24.40 per 100 000 (95% confidence interval (CI): 21.36-27.43) for Period 1 and 22.06 per 100 000 (95% CI: 19.32-24.81) for Period 2. The period prevalence was 442.65 per 100 000 (95% CI: 420.08-465.04) for Period 1 and 448.66 per 100 000 (95% CI: 427.31-470.01) for Period 2. The all-cause SMR for individuals with incident RA was 1.25 (95% CI: 0.95-1.60). The SMR for all prevalent RA during Period 1 was 2.01 (95% CI: 1.85-2.19) and for Period 2 was 1.87 (95% CI: 1.69-2.06).

Conclusions: The frequency of RA in the Canterbury population is comparable to other regions. Mortality for all individuals with prevalent RA was approximately two times higher than the general population.

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来源期刊
Internal Medicine Journal
Internal Medicine Journal 医学-医学:内科
CiteScore
3.50
自引率
4.80%
发文量
600
审稿时长
3-6 weeks
期刊介绍: The Internal Medicine Journal is the official journal of the Adult Medicine Division of The Royal Australasian College of Physicians (RACP). Its purpose is to publish high-quality internationally competitive peer-reviewed original medical research, both laboratory and clinical, relating to the study and research of human disease. Papers will be considered from all areas of medical practice and science. The Journal also has a major role in continuing medical education and publishes review articles relevant to physician education.
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