{"title":"是什么让秀丽隐杆线虫保持精确:排便的时空调节。","authors":"Qiang Liu, Louis Tao","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Rhythmic behaviors controlled by internal biological clocks are universal among living organisms, ranging from single cells to humans. The inner workings and modulations of the intrinsic oscillatory activities that underlie these rhythmic behaviors are diverse and not well understood across different systems. The <i>Caenorhabditis elegans</i> defecation behavior, also known as the defecation motor program, is a particularly intriguing rhythmic behavior that has been studied for over 30 years since James Thomas' pioneering work in 1990. Numerous conserved genes and signaling molecules have been identified through meticulous studies of every detail of its genetics, physiology, and behavior. Since earlier works have been reviewed until 2006 in the literature, this review is not intended to be comprehensive and will instead focus on progress since then, with emphases on intestinal calcium and proton oscillations as well as the modulation of the defecation rhythm by the enteric nervous system.</p>","PeriodicalId":15171,"journal":{"name":"Journal of Biosciences","volume":"50 ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"What keeps <i>Caenorhabditis elegans</i> precise: The spatiotemporal regulation of defecation.\",\"authors\":\"Qiang Liu, Louis Tao\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Rhythmic behaviors controlled by internal biological clocks are universal among living organisms, ranging from single cells to humans. The inner workings and modulations of the intrinsic oscillatory activities that underlie these rhythmic behaviors are diverse and not well understood across different systems. The <i>Caenorhabditis elegans</i> defecation behavior, also known as the defecation motor program, is a particularly intriguing rhythmic behavior that has been studied for over 30 years since James Thomas' pioneering work in 1990. Numerous conserved genes and signaling molecules have been identified through meticulous studies of every detail of its genetics, physiology, and behavior. Since earlier works have been reviewed until 2006 in the literature, this review is not intended to be comprehensive and will instead focus on progress since then, with emphases on intestinal calcium and proton oscillations as well as the modulation of the defecation rhythm by the enteric nervous system.</p>\",\"PeriodicalId\":15171,\"journal\":{\"name\":\"Journal of Biosciences\",\"volume\":\"50 \",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Biosciences\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biosciences","FirstCategoryId":"99","ListUrlMain":"","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOLOGY","Score":null,"Total":0}
What keeps Caenorhabditis elegans precise: The spatiotemporal regulation of defecation.
Rhythmic behaviors controlled by internal biological clocks are universal among living organisms, ranging from single cells to humans. The inner workings and modulations of the intrinsic oscillatory activities that underlie these rhythmic behaviors are diverse and not well understood across different systems. The Caenorhabditis elegans defecation behavior, also known as the defecation motor program, is a particularly intriguing rhythmic behavior that has been studied for over 30 years since James Thomas' pioneering work in 1990. Numerous conserved genes and signaling molecules have been identified through meticulous studies of every detail of its genetics, physiology, and behavior. Since earlier works have been reviewed until 2006 in the literature, this review is not intended to be comprehensive and will instead focus on progress since then, with emphases on intestinal calcium and proton oscillations as well as the modulation of the defecation rhythm by the enteric nervous system.
期刊介绍:
The Journal of Biosciences is a quarterly journal published by the Indian Academy of Sciences, Bangalore. It covers all areas of Biology and is the premier journal in the country within its scope. It is indexed in Current Contents and other standard Biological and Medical databases. The Journal of Biosciences began in 1934 as the Proceedings of the Indian Academy of Sciences (Section B). This continued until 1978 when it was split into three parts : Proceedings-Animal Sciences, Proceedings-Plant Sciences and Proceedings-Experimental Biology. Proceedings-Experimental Biology was renamed Journal of Biosciences in 1979; and in 1991, Proceedings-Animal Sciences and Proceedings-Plant Sciences merged with it.