Sjögren's disease, occupational performance and quality of life.

Introduction: Sjögren's disease is an autoimmune disease with dry eyes and mouth and chronic pain, more frequent in middle-aged women. The aim of this study is to understand the impact of Sjögren's disease on quality of life and occupational health.

Method: Quantitative and qualitative comparative study, with 20 Sjögren's disease and 25 healthy controls. Questionnaires and interviews were applied to assess occupational performance, quality of life, mood disorders, and sleep.

Results: The combined major diagnostic parameters for Sjögren's disease (focus score and anti-SSA/Ro positivity) were present in 85% of the Sjögren's disease group. There was a correlation between the sicca symptom measured by the European League Against Rheumatism Sjögren's Syndrome Patient Reported Index (ESSPRI), anxiety, and depression measured by the Hospital Anxiety and Depression Scale (HADS; r = 0.56; p = 0.009), as well as fatigue measured by the Profile of fatigue and discomfort questionnaire (PROFAD) (r = 0.78; p < 0.0001). Sjögren's disease patients reported a loss of physical abilities, sleep disturbance, change in mood, social and occupational participation, and lower quality of life.

Conclusions: Sjögren's disease patients have poorer quality of life, loss of competencies, and sleep disturbances compared to controls. Novel strategies are necessary to improve occupational health in SjD.