Min Sun, Chengbin Long, Yinshuang Zou, Yong Hu, Cheng Chen, Ning Hu
{"title":"一项回顾性队列研究表明,髋关节置换术后老年患者髋关节囊外骨折比髋关节囊内骨折更容易发生围手术期血栓形成。","authors":"Min Sun, Chengbin Long, Yinshuang Zou, Yong Hu, Cheng Chen, Ning Hu","doi":"10.1007/s00590-025-04288-3","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Whether fracture site has any effect on perioperative deep vein thrombosis (DVT) in elderly patients with hip fractures undergoing arthroplasty is still controversial. This study aimed to evaluate the association between fracture site and perioperative DVT in elderly patients undergoing hip arthroplasty.</p><p><strong>Methods: </strong>A retrospective cohort analysis was conducted on elderly hip fracture patients who underwent hip arthroplasty and were admitted between January 2015 and December 2021. Patient data, including demographics, comorbidities, injury-related information, laboratory test results at admission, and surgery-related information, were collected. Univariate and multivariate regression analyses, along with subgroup analyses and sensitive analysis, were performed to identify the association between fracture site and DVT.</p><p><strong>Results: </strong>The study included 593 patients, consisting of 353 patients with intracapsular hip fractures (ICF) and 240 patients with extracapsular hip fractures (ECF), with an average age of 80.7 ± 7.6. The incidence of DVT diagnosed by ultrasonography was 16.9% in all patients. The prevalence of DVT for ECF patients and ICF patients was 22.5% and 13.0%, respectively. In all adjusted multivariate regression analysis model, ECF patients exhibited an increased risk of DVT compared to ICF patients (OR 2.03; 95% CI 1.19-3.47, p = 0.009). Subgroup analyses revealed that female patients with ECF had a higher likelihood of DVT than those with ICF (OR 2.25; 95% CI 1.22-4.13), as did patients aged 65 to 80 years (OR 4.06; 95% CI 1.44-11.41), patients with hemoglobin levels above 110 g/L (OR 2.30; 95% CI 1.08-4.92), and patients with albumin levels above 35 g/L (OR 2.47; 95% CI 1.29-4.73). Sensitivity analysis found similar results.</p><p><strong>Conclusion: </strong>The findings indicate a significant association between fracture site and perioperative DVT in elderly hip fracture patients undergoing hip arthroplasty, with ECF patients demonstrating a higher likelihood of developing DVT than ICF patients.</p>","PeriodicalId":50484,"journal":{"name":"European Journal of Orthopaedic Surgery and Traumatology","volume":"35 1","pages":"186"},"PeriodicalIF":1.4000,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Extracapsular hip fractures are more prone to perioperative thrombosis than intracapsular hip fractures in elderly patients undergoing arthroplasty for hip fractures: a retrospective cohort study.\",\"authors\":\"Min Sun, Chengbin Long, Yinshuang Zou, Yong Hu, Cheng Chen, Ning Hu\",\"doi\":\"10.1007/s00590-025-04288-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Whether fracture site has any effect on perioperative deep vein thrombosis (DVT) in elderly patients with hip fractures undergoing arthroplasty is still controversial. This study aimed to evaluate the association between fracture site and perioperative DVT in elderly patients undergoing hip arthroplasty.</p><p><strong>Methods: </strong>A retrospective cohort analysis was conducted on elderly hip fracture patients who underwent hip arthroplasty and were admitted between January 2015 and December 2021. Patient data, including demographics, comorbidities, injury-related information, laboratory test results at admission, and surgery-related information, were collected. Univariate and multivariate regression analyses, along with subgroup analyses and sensitive analysis, were performed to identify the association between fracture site and DVT.</p><p><strong>Results: </strong>The study included 593 patients, consisting of 353 patients with intracapsular hip fractures (ICF) and 240 patients with extracapsular hip fractures (ECF), with an average age of 80.7 ± 7.6. The incidence of DVT diagnosed by ultrasonography was 16.9% in all patients. The prevalence of DVT for ECF patients and ICF patients was 22.5% and 13.0%, respectively. In all adjusted multivariate regression analysis model, ECF patients exhibited an increased risk of DVT compared to ICF patients (OR 2.03; 95% CI 1.19-3.47, p = 0.009). Subgroup analyses revealed that female patients with ECF had a higher likelihood of DVT than those with ICF (OR 2.25; 95% CI 1.22-4.13), as did patients aged 65 to 80 years (OR 4.06; 95% CI 1.44-11.41), patients with hemoglobin levels above 110 g/L (OR 2.30; 95% CI 1.08-4.92), and patients with albumin levels above 35 g/L (OR 2.47; 95% CI 1.29-4.73). Sensitivity analysis found similar results.</p><p><strong>Conclusion: </strong>The findings indicate a significant association between fracture site and perioperative DVT in elderly hip fracture patients undergoing hip arthroplasty, with ECF patients demonstrating a higher likelihood of developing DVT than ICF patients.</p>\",\"PeriodicalId\":50484,\"journal\":{\"name\":\"European Journal of Orthopaedic Surgery and Traumatology\",\"volume\":\"35 1\",\"pages\":\"186\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-05-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Orthopaedic Surgery and Traumatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s00590-025-04288-3\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Orthopaedic Surgery and Traumatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00590-025-04288-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
摘要
目的:骨折部位对老年髋部骨折置换术患者围手术期深静脉血栓形成(DVT)的影响尚存争议。本研究旨在评估老年髋关节置换术患者骨折部位与围手术期DVT的关系。方法:回顾性队列分析2015年1月至2021年12月住院的行髋关节置换术的老年髋部骨折患者。收集患者资料,包括人口统计学、合并症、损伤相关信息、入院时实验室检查结果和手术相关信息。通过单变量和多变量回归分析,以及亚组分析和敏感性分析,确定骨折部位与DVT之间的关系。结果:纳入593例患者,其中髋囊内骨折(ICF) 353例,髋囊外骨折(ECF) 240例,平均年龄80.7±7.6岁。超声诊断深静脉血栓的发生率为16.9%。ECF患者和ICF患者的DVT患病率分别为22.5%和13.0%。在所有调整后的多元回归分析模型中,ECF患者发生DVT的风险高于ICF患者(OR 2.03;95% CI 1.19-3.47, p = 0.009)。亚组分析显示,女性ECF患者发生DVT的可能性高于ICF患者(OR 2.25;95% CI 1.22-4.13), 65 - 80岁患者也是如此(OR 4.06;95% CI 1.44-11.41),血红蛋白水平高于110 g/L的患者(OR 2.30;95% CI 1.08-4.92),白蛋白水平高于35 g/L的患者(OR 2.47;95% ci 1.29-4.73)。敏感性分析也发现了类似的结果。结论:研究结果表明,老年髋部骨折行髋关节置换术患者骨折部位与围手术期DVT存在显著相关性,ECF患者发生DVT的可能性高于ICF患者。
Extracapsular hip fractures are more prone to perioperative thrombosis than intracapsular hip fractures in elderly patients undergoing arthroplasty for hip fractures: a retrospective cohort study.
Purpose: Whether fracture site has any effect on perioperative deep vein thrombosis (DVT) in elderly patients with hip fractures undergoing arthroplasty is still controversial. This study aimed to evaluate the association between fracture site and perioperative DVT in elderly patients undergoing hip arthroplasty.
Methods: A retrospective cohort analysis was conducted on elderly hip fracture patients who underwent hip arthroplasty and were admitted between January 2015 and December 2021. Patient data, including demographics, comorbidities, injury-related information, laboratory test results at admission, and surgery-related information, were collected. Univariate and multivariate regression analyses, along with subgroup analyses and sensitive analysis, were performed to identify the association between fracture site and DVT.
Results: The study included 593 patients, consisting of 353 patients with intracapsular hip fractures (ICF) and 240 patients with extracapsular hip fractures (ECF), with an average age of 80.7 ± 7.6. The incidence of DVT diagnosed by ultrasonography was 16.9% in all patients. The prevalence of DVT for ECF patients and ICF patients was 22.5% and 13.0%, respectively. In all adjusted multivariate regression analysis model, ECF patients exhibited an increased risk of DVT compared to ICF patients (OR 2.03; 95% CI 1.19-3.47, p = 0.009). Subgroup analyses revealed that female patients with ECF had a higher likelihood of DVT than those with ICF (OR 2.25; 95% CI 1.22-4.13), as did patients aged 65 to 80 years (OR 4.06; 95% CI 1.44-11.41), patients with hemoglobin levels above 110 g/L (OR 2.30; 95% CI 1.08-4.92), and patients with albumin levels above 35 g/L (OR 2.47; 95% CI 1.29-4.73). Sensitivity analysis found similar results.
Conclusion: The findings indicate a significant association between fracture site and perioperative DVT in elderly hip fracture patients undergoing hip arthroplasty, with ECF patients demonstrating a higher likelihood of developing DVT than ICF patients.
期刊介绍:
The European Journal of Orthopaedic Surgery and Traumatology (EJOST) aims to publish high quality Orthopedic scientific work. The objective of our journal is to disseminate meaningful, impactful, clinically relevant work from each and every region of the world, that has the potential to change and or inform clinical practice.