Su Ji Lee, Jihye Hwang, Min Gyu Kang, Minjae Cho, Yoon Ha, Sung-Rae Cho
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Duration (OR 1.99, 95% CI 1.25-3.65, <i>P</i> = .01), signal change grade 2 (OR 10.44, 95% CI 1.32-118.01, <i>P</i> = .034), and spinal cord compression ratio, M2 (OR 0.85, 95% CI, 0.73-0.96, <i>P</i> = .02) on preoperative MRI were identified as significant factors associated with the risk of poor postoperative outcomes. Based on the receiver operating characteristic curve analysis, the cutoff values for duration and cord compression metric were determined as 2 years (AUC = 0.689, 95% CI 0.532-0.845) and 76.2% (AUC = 0.841, 95% CI 0.696-0.987), respectively.ConclusionsThis study identified key predictors of poor postoperative outcomes in individuals with CP undergoing surgery for CSM. Symptom duration exceeding 2 years, signal change grade 2, and spinal cord compression ratio below 76.2% on preoperative MRI were found to be predictors of poor outcome. These results underscore the importance of early intervention and detailed preoperative radiological assessment to improve surgical outcomes in this population.</p>","PeriodicalId":12680,"journal":{"name":"Global Spine Journal","volume":" ","pages":"21925682251337396"},"PeriodicalIF":2.6000,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048400/pdf/","citationCount":"0","resultStr":"{\"title\":\"Predictive Factors for Postoperative Outcomes of Cervical Spondylotic Myelopathy in Individuals With Cerebral Palsy.\",\"authors\":\"Su Ji Lee, Jihye Hwang, Min Gyu Kang, Minjae Cho, Yoon Ha, Sung-Rae Cho\",\"doi\":\"10.1177/21925682251337396\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Study DesignRetrospective cohort study.ObjectivesThis study aimed to identify factors influencing postoperative outcomes of cervical spondylotic myelopathy (CSM) in individuals with cerebral palsy (CP).MethodsData from admitted individuals were retrospectively reviewed. Individuals whose modified Barthel index score, assessed at least 6 months after surgery, declined by 1 or more grades compared to their preoperative score were classified into the poor outcome (PO) group. Multivariate logistic regression analysis was performed to assess risk factors for poor postoperative outcomes.ResultsOf the 73 participants, 15 were in the PO group and 58 in the non-PO group. Duration (OR 1.99, 95% CI 1.25-3.65, <i>P</i> = .01), signal change grade 2 (OR 10.44, 95% CI 1.32-118.01, <i>P</i> = .034), and spinal cord compression ratio, M2 (OR 0.85, 95% CI, 0.73-0.96, <i>P</i> = .02) on preoperative MRI were identified as significant factors associated with the risk of poor postoperative outcomes. Based on the receiver operating characteristic curve analysis, the cutoff values for duration and cord compression metric were determined as 2 years (AUC = 0.689, 95% CI 0.532-0.845) and 76.2% (AUC = 0.841, 95% CI 0.696-0.987), respectively.ConclusionsThis study identified key predictors of poor postoperative outcomes in individuals with CP undergoing surgery for CSM. Symptom duration exceeding 2 years, signal change grade 2, and spinal cord compression ratio below 76.2% on preoperative MRI were found to be predictors of poor outcome. 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引用次数: 0
摘要
研究设计回顾性队列研究。目的探讨影响脑瘫(CP)患者脊髓型颈椎病(CSM)术后预后的因素。方法回顾性分析入院患者的资料。术后至少6个月评估的改良Barthel指数评分与术前评分相比下降1级或更多的个体被归为预后不良(PO)组。采用多因素logistic回归分析评估术后不良预后的危险因素。结果73例患者中,PO组15例,非PO组58例。术前MRI持续时间(OR 1.99, 95% CI 1.25-3.65, P = 0.01)、信号改变等级2 (OR 10.44, 95% CI 1.32-118.01, P = 0.034)和脊髓压缩比M2 (OR 0.85, 95% CI 0.73-0.96, P = 0.02)被认为是与术后不良风险相关的重要因素。根据受试者工作特征曲线分析,确定病程和脐带压缩指标的截止值分别为2年(AUC = 0.689, 95% CI 0.532-0.845)和76.2% (AUC = 0.841, 95% CI 0.696-0.987)。结论:本研究确定了CP患者接受CSM手术后不良预后的关键预测因素。症状持续时间超过2年,信号改变2级,术前MRI脊髓压缩比低于76.2%是预后不良的预测因素。这些结果强调了早期干预和详细的术前放射学评估对改善该人群手术结果的重要性。
Predictive Factors for Postoperative Outcomes of Cervical Spondylotic Myelopathy in Individuals With Cerebral Palsy.
Study DesignRetrospective cohort study.ObjectivesThis study aimed to identify factors influencing postoperative outcomes of cervical spondylotic myelopathy (CSM) in individuals with cerebral palsy (CP).MethodsData from admitted individuals were retrospectively reviewed. Individuals whose modified Barthel index score, assessed at least 6 months after surgery, declined by 1 or more grades compared to their preoperative score were classified into the poor outcome (PO) group. Multivariate logistic regression analysis was performed to assess risk factors for poor postoperative outcomes.ResultsOf the 73 participants, 15 were in the PO group and 58 in the non-PO group. Duration (OR 1.99, 95% CI 1.25-3.65, P = .01), signal change grade 2 (OR 10.44, 95% CI 1.32-118.01, P = .034), and spinal cord compression ratio, M2 (OR 0.85, 95% CI, 0.73-0.96, P = .02) on preoperative MRI were identified as significant factors associated with the risk of poor postoperative outcomes. Based on the receiver operating characteristic curve analysis, the cutoff values for duration and cord compression metric were determined as 2 years (AUC = 0.689, 95% CI 0.532-0.845) and 76.2% (AUC = 0.841, 95% CI 0.696-0.987), respectively.ConclusionsThis study identified key predictors of poor postoperative outcomes in individuals with CP undergoing surgery for CSM. Symptom duration exceeding 2 years, signal change grade 2, and spinal cord compression ratio below 76.2% on preoperative MRI were found to be predictors of poor outcome. These results underscore the importance of early intervention and detailed preoperative radiological assessment to improve surgical outcomes in this population.
期刊介绍:
Global Spine Journal (GSJ) is the official scientific publication of AOSpine. A peer-reviewed, open access journal, devoted to the study and treatment of spinal disorders, including diagnosis, operative and non-operative treatment options, surgical techniques, and emerging research and clinical developments.GSJ is indexed in PubMedCentral, SCOPUS, and Emerging Sources Citation Index (ESCI).